(38 nodes) Exocrine system development network (Callithrix jacchus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	EDAR	Ectodysplasin A receptor. (480 aa)
	SEMA3C	Semaphorin-3C; Belongs to the semaphorin family. (751 aa)
	PLXND1	Plexin D1. (1808 aa)
	IGSF3	Immunoglobulin superfamily member 3. (1216 aa)
	PTF1A	Pancreas associated transcription factor 1a. (332 aa)
	POLB	DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
	NFIB	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (927 aa)
	CLCN2	Chloride channel protein. (881 aa)
	RAB26	RAB26, member RAS oncogene family. (256 aa)
	LAMA1	Laminin subunit alpha 1. (3080 aa)
	F7C2L0_CALJA	Uncharacterized protein. (650 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	CELA1	Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (254 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
	TGM2	Transglutaminase 2. (687 aa)
	H9KY09_CALJA	Uncharacterized protein. (692 aa)
	TNF	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (232 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
	SELENOH	Uncharacterized protein. (121 aa)
	EDA	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (389 aa)
	PAX6	Paired box 6. (472 aa)
	ENSCJAP00000065030	Plexin_cytopl domain-containing protein. (55 aa)
	FGFR2	Fibroblast growth factor receptor. (822 aa)
	NKX3-1	NK3 homeobox 1. (286 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	TGFB3	Transforming growth factor beta 3. (428 aa)
	DAG1	Dystroglycan preproprotein. (895 aa)
	BMP7	Bone morphogenetic protein 7. (430 aa)
	ENSCJAP00000071558	TGF_BETA_2 domain-containing protein. (151 aa)
	IGF2	Insulin like growth factor 2. (348 aa)
	PLXNA1	Plexin A1. (2224 aa)
	PDX1	Homeobox domain-containing protein. (282 aa)
	SOX10	Transcription factor SOX-10. (467 aa)
	TWSG1	Twisted gastrulation BMP signaling modulator 1. (219 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP7	FGFR2	ENSCJAP00000070399	ENSCJAP00000065661	Bone morphogenetic protein 7.	Fibroblast growth factor receptor.	0.660
BMP7	SHH	ENSCJAP00000070399	ENSCJAP00000037954	Bone morphogenetic protein 7.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.504
DAG1	LAMA1	ENSCJAP00000069888	ENSCJAP00000028744	Dystroglycan preproprotein.	Laminin subunit alpha 1.	0.924
EDA	EDAR	ENSCJAP00000057359	ENSCJAP00000002262	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	Ectodysplasin A receptor.	0.904
EDAR	EDA	ENSCJAP00000002262	ENSCJAP00000057359	Ectodysplasin A receptor.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.904
ENSCJAP00000065030	NRP1	ENSCJAP00000065030	ENSCJAP00000025395	Plexin_cytopl domain-containing protein.	Neuropilin; Belongs to the neuropilin family.	0.790
ENSCJAP00000065030	SEMA3C	ENSCJAP00000065030	ENSCJAP00000006043	Plexin_cytopl domain-containing protein.	Semaphorin-3C; Belongs to the semaphorin family.	0.649
ENSCJAP00000071558	TGFB1	ENSCJAP00000071558	ENSCJAP00000037471	TGF_BETA_2 domain-containing protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.643
ENSCJAP00000071558	TGFB3	ENSCJAP00000071558	ENSCJAP00000069020	TGF_BETA_2 domain-containing protein.	Transforming growth factor beta 3.	0.618
FGF10	FGF7	ENSCJAP00000053129	ENSCJAP00000075380	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.467
FGF10	FGF8	ENSCJAP00000053129	ENSCJAP00000032516	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.628
FGF10	FGFR2	ENSCJAP00000053129	ENSCJAP00000065661	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.989
FGF10	NRP1	ENSCJAP00000053129	ENSCJAP00000025395	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Neuropilin; Belongs to the neuropilin family.	0.480
FGF10	PAX6	ENSCJAP00000053129	ENSCJAP00000057969	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Paired box 6.	0.402
FGF10	PDX1	ENSCJAP00000053129	ENSCJAP00000074029	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox domain-containing protein.	0.531
FGF10	SHH	ENSCJAP00000053129	ENSCJAP00000037954	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.702
FGF10	TGFB1	ENSCJAP00000053129	ENSCJAP00000037471	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.478
FGF7	FGF10	ENSCJAP00000075380	ENSCJAP00000053129	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.467
FGF7	FGF8	ENSCJAP00000075380	ENSCJAP00000032516	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.520
FGF7	FGFR2	ENSCJAP00000075380	ENSCJAP00000065661	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.963