(42 nodes) Endodermal cell differentiation network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCJAP00000078638	Uncharacterized protein. (134 aa)
	LEO1	LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
	F7H4W0_CALJA	VWFA domain-containing protein. (268 aa)
	SETD2	SET domain containing 2, histone lysine methyltransferase. (2561 aa)
	MMP8	Matrix metallopeptidase 8. (466 aa)
	RTF1	RTF1 homolog, Paf1/RNA polymerase II complex component. (712 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (799 aa)
	ITGA7	Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa)
	MMP14	Matrix metalloproteinase-14 preproprotein. (582 aa)
	COL11A1	Collagen type XI alpha 1 chain. (1817 aa)
	COL12A1	Collagen type XII alpha 1 chain. (3063 aa)
	CTR9	CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
	FN1	Fibronectin isoform 1 preproprotein. (2478 aa)
	MIXL1	Mix paired-like homeobox. (236 aa)
	NODAL	Nodal growth differentiation factor. (346 aa)
	MMP9	Matrix metallopeptidase 9. (703 aa)
	CTNNB1	Catenin beta 1. (774 aa)
	ITGA5	Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1049 aa)
	GATA6	GATA binding protein 6. (592 aa)
	LAMA3	Laminin subunit alpha 3. (3339 aa)
	ITGAV	Integrin alpha-V isoform 1; Belongs to the integrin alpha chain family. (1047 aa)
	LAMB3	Laminin subunit beta 3. (1172 aa)
	EOMES	Eomesodermin. (706 aa)
	PAF1	RNA polymerase II-associated factor 1 homolog isoform 1. (529 aa)
	INHBA	Inhibin subunit beta A. (426 aa)
	NR0B1	Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. (470 aa)
	ENSCJAP00000064549	Uncharacterized protein. (118 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform 1. (217 aa)
	ENSCJAP00000067987	Uncharacterized protein. (74 aa)
	ENSCJAP00000068891	Uncharacterized protein. (94 aa)
	ENSCJAP00000069100	Uncharacterized protein. (104 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1033 aa)
	ENSCJAP00000070597	Uncharacterized protein. (87 aa)
	COL8A1	Collagen alpha-1(VIII) chain. (744 aa)
	ENSCJAP00000073742	CDC73_N domain-containing protein. (390 aa)
	COL4A2	Collagen type IV alpha 2 chain. (1798 aa)
	MMP15	Matrix metallopeptidase 15. (672 aa)
	ITGB2	Integrin beta. (866 aa)
	CDC73	Cell division cycle 73. (550 aa)
	SOX17	SRY-box transcription factor 17. (414 aa)
	ENSCJAP00000076525	Uncharacterized protein. (94 aa)
	MMP2	72 kDa type IV collagenase isoform a preproprotein. (660 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC73	CTNNB1	ENSCJAP00000076350	ENSCJAP00000033154	Cell division cycle 73.	Catenin beta 1.	0.743
CDC73	CTR9	ENSCJAP00000076350	ENSCJAP00000020046	Cell division cycle 73.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.993
CDC73	LEO1	ENSCJAP00000076350	ENSCJAP00000001668	Cell division cycle 73.	LEO1 homolog, Paf1/RNA polymerase II complex component.	0.999
CDC73	PAF1	ENSCJAP00000076350	ENSCJAP00000056734	Cell division cycle 73.	RNA polymerase II-associated factor 1 homolog isoform 1.	0.975
CDC73	RTF1	ENSCJAP00000076350	ENSCJAP00000012159	Cell division cycle 73.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.981
CDC73	SETD2	ENSCJAP00000076350	ENSCJAP00000004214	Cell division cycle 73.	SET domain containing 2, histone lysine methyltransferase.	0.493
COL11A1	COL12A1	ENSCJAP00000016450	ENSCJAP00000018939	Collagen type XI alpha 1 chain.	Collagen type XII alpha 1 chain.	0.413
COL11A1	COL8A1	ENSCJAP00000016450	ENSCJAP00000070965	Collagen type XI alpha 1 chain.	Collagen alpha-1(VIII) chain.	0.411
COL11A1	F7H4W0_CALJA	ENSCJAP00000016450	ENSCJAP00000003411	Collagen type XI alpha 1 chain.	VWFA domain-containing protein.	0.412
COL11A1	ITGA5	ENSCJAP00000016450	ENSCJAP00000035228	Collagen type XI alpha 1 chain.	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	0.451
COL11A1	LAMA3	ENSCJAP00000016450	ENSCJAP00000038344	Collagen type XI alpha 1 chain.	Laminin subunit alpha 3.	0.424
COL12A1	COL11A1	ENSCJAP00000018939	ENSCJAP00000016450	Collagen type XII alpha 1 chain.	Collagen type XI alpha 1 chain.	0.413
COL12A1	COL4A2	ENSCJAP00000018939	ENSCJAP00000079036	Collagen type XII alpha 1 chain.	Collagen type IV alpha 2 chain.	0.746
COL12A1	COL8A1	ENSCJAP00000018939	ENSCJAP00000070965	Collagen type XII alpha 1 chain.	Collagen alpha-1(VIII) chain.	0.452
COL12A1	MMP2	ENSCJAP00000018939	ENSCJAP00000076531	Collagen type XII alpha 1 chain.	72 kDa type IV collagenase isoform a preproprotein.	0.442
COL4A2	COL12A1	ENSCJAP00000079036	ENSCJAP00000018939	Collagen type IV alpha 2 chain.	Collagen type XII alpha 1 chain.	0.746
COL4A2	COL8A1	ENSCJAP00000079036	ENSCJAP00000070965	Collagen type IV alpha 2 chain.	Collagen alpha-1(VIII) chain.	0.507
COL4A2	F7H4W0_CALJA	ENSCJAP00000079036	ENSCJAP00000003411	Collagen type IV alpha 2 chain.	VWFA domain-containing protein.	0.443
COL4A2	FN1	ENSCJAP00000079036	ENSCJAP00000022457	Collagen type IV alpha 2 chain.	Fibronectin isoform 1 preproprotein.	0.428
COL4A2	ITGAV	ENSCJAP00000079036	ENSCJAP00000042284	Collagen type IV alpha 2 chain.	Integrin alpha-V isoform 1; Belongs to the integrin alpha chain family.	0.410