STRINGSTRING
MAPK7 MAPK7 ATF4 ATF4 ATF6 ATF6 NFE2L1 NFE2L1 GCN1 GCN1 NOTCH1 NOTCH1 CREB3L1 CREB3L1 CREB3L3 CREB3L3 HIF1A HIF1A XBP1 XBP1 ENSCJAP00000039892 ENSCJAP00000039892 DDIT3 DDIT3 ATF6B ATF6B ATF3 ATF3 SESN2 SESN2 CHD6 CHD6 CEBPB CEBPB MBTPS2 MBTPS2 NFE2L2 NFE2L2 MUC1 MUC1 ENSCJAP00000071395 ENSCJAP00000071395 ENSCJAP00000062412 ENSCJAP00000062412 RBPJ RBPJ ENSCJAP00000059748 ENSCJAP00000059748
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
ATF4Activating transcription factor 4. (351 aa)
ATF6Activating transcription factor 6. (669 aa)
NFE2L1Nuclear factor erythroid 2-related factor 1. (772 aa)
GCN1GCN1 activator of EIF2AK4. (2671 aa)
NOTCH1Notch receptor 1. (2551 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (461 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
XBP1BZIP domain-containing protein. (371 aa)
ENSCJAP00000039892Heat shock transcription factor 1. (557 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta isoform a. (700 aa)
ATF3Cyclic AMP-dependent transcription factor ATF-3 isoform 1. (181 aa)
SESN2Sestrin-2. (480 aa)
CHD6Chromodomain-helicase-DNA-binding protein 6. (2714 aa)
CEBPBCCAAT/enhancer-binding protein. (344 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (513 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (622 aa)
MUC1SEA domain-containing protein. (257 aa)
ENSCJAP00000071395BZIP domain-containing protein. (345 aa)
ENSCJAP00000062412Kruppel like factor 2. (353 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (500 aa)
ENSCJAP00000059748DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (195 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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