(8 nodes) Meiotic telomere clustering network (Callithrix jacchus)

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Predicted Interactions

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Your Input:
	TERB2	Telomere repeat binding bouquet formation protein 2. (221 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
	TERB1	Telomere repeat binding bouquet formation protein 1. (725 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (396 aa)
	SUN1	Sad1 and UNC84 domain containing 1. (910 aa)
	MLH1	MutL homolog 1. (820 aa)
	TERF1	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (452 aa)
	ENSCJAP00000074663	Uncharacterized protein. (347 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	MLH1	ENSCJAP00000018844	ENSCJAP00000069380	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	MutL homolog 1.	0.894
ATM	SPO11	ENSCJAP00000018844	ENSCJAP00000035571	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	SPO11 initiator of meiotic double stranded breaks.	0.763
ATM	TERF1	ENSCJAP00000018844	ENSCJAP00000071851	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.657
ENSCJAP00000074663	SUN1	ENSCJAP00000074663	ENSCJAP00000054726	Uncharacterized protein.	Sad1 and UNC84 domain containing 1.	0.547
ENSCJAP00000074663	TERB1	ENSCJAP00000074663	ENSCJAP00000030827	Uncharacterized protein.	Telomere repeat binding bouquet formation protein 1.	0.645
ENSCJAP00000074663	TERB2	ENSCJAP00000074663	ENSCJAP00000004257	Uncharacterized protein.	Telomere repeat binding bouquet formation protein 2.	0.925
ENSCJAP00000074663	TERF1	ENSCJAP00000074663	ENSCJAP00000071851	Uncharacterized protein.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.447
MLH1	ATM	ENSCJAP00000069380	ENSCJAP00000018844	MutL homolog 1.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.894
MLH1	SPO11	ENSCJAP00000069380	ENSCJAP00000035571	MutL homolog 1.	SPO11 initiator of meiotic double stranded breaks.	0.692
SPO11	ATM	ENSCJAP00000035571	ENSCJAP00000018844	SPO11 initiator of meiotic double stranded breaks.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.763
SPO11	MLH1	ENSCJAP00000035571	ENSCJAP00000069380	SPO11 initiator of meiotic double stranded breaks.	MutL homolog 1.	0.692
SUN1	ENSCJAP00000074663	ENSCJAP00000054726	ENSCJAP00000074663	Sad1 and UNC84 domain containing 1.	Uncharacterized protein.	0.547
SUN1	TERB1	ENSCJAP00000054726	ENSCJAP00000030827	Sad1 and UNC84 domain containing 1.	Telomere repeat binding bouquet formation protein 1.	0.666
SUN1	TERB2	ENSCJAP00000054726	ENSCJAP00000004257	Sad1 and UNC84 domain containing 1.	Telomere repeat binding bouquet formation protein 2.	0.521
TERB1	ENSCJAP00000074663	ENSCJAP00000030827	ENSCJAP00000074663	Telomere repeat binding bouquet formation protein 1.	Uncharacterized protein.	0.645
TERB1	SUN1	ENSCJAP00000030827	ENSCJAP00000054726	Telomere repeat binding bouquet formation protein 1.	Sad1 and UNC84 domain containing 1.	0.666
TERB1	TERB2	ENSCJAP00000030827	ENSCJAP00000004257	Telomere repeat binding bouquet formation protein 1.	Telomere repeat binding bouquet formation protein 2.	0.912
TERB1	TERF1	ENSCJAP00000030827	ENSCJAP00000071851	Telomere repeat binding bouquet formation protein 1.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.940
TERB2	ENSCJAP00000074663	ENSCJAP00000004257	ENSCJAP00000074663	Telomere repeat binding bouquet formation protein 2.	Uncharacterized protein.	0.925
TERB2	SUN1	ENSCJAP00000004257	ENSCJAP00000054726	Telomere repeat binding bouquet formation protein 2.	Sad1 and UNC84 domain containing 1.	0.521