STRINGSTRING
ENSCJAP00000062228 ENSCJAP00000062228 BAX BAX HRAS HRAS PDGFB PDGFB JUN JUN EREG EREG C1QL4 C1QL4 ABL1 ABL1 CD74 CD74 IFI30 IFI30 RNASEH2B RNASEH2B CD248 CD248 ENSCJAP00000068516 ENSCJAP00000068516 TRIM32 TRIM32 DDR2 DDR2 FBLN1 FBLN1 NDUFS4 NDUFS4 ENSCJAP00000070085 ENSCJAP00000070085 ENSCJAP00000070637 ENSCJAP00000070637 PDGFRB PDGFRB PARP10 PARP10 ENSCJAP00000073742 ENSCJAP00000073742 ENSCJAP00000074274 ENSCJAP00000074274 TP53INP1 TP53INP1 ENSCJAP00000075173 ENSCJAP00000075173 CDC73 CDC73 JUND JUND MIF MIF PEX2 PEX2 ZMIZ1 ZMIZ1 FBXO4 FBXO4 FNDC3B FNDC3B SKI SKI FBRS FBRS WNT5A WNT5A MORC3 MORC3 ZMPSTE24 ZMPSTE24 CCNA2 CCNA2 WAPL WAPL MED25 MED25 PDGFA PDGFA DHX9 DHX9 PLA2G1B PLA2G1B S100A6 S100A6 LIF LIF SFRP1 SFRP1 B4GALT7 B4GALT7 XRCC4 XRCC4 EMD EMD FN1 FN1 MYC MYC CDC6 CDC6 SPHK1 SPHK1 NF1 NF1 WNT2 WNT2 CTC1 CTC1 CD300A CD300A SIRT6 SIRT6 CCNB1 CCNB1 PML PML CTNNB1 CTNNB1 E2F1 E2F1 GAS6 GAS6 PAWR PAWR ESR1 ESR1 NLRC3 NLRC3 ITGB3 ITGB3 TGFB1 TGFB1 DAB2IP DAB2IP WNT1 WNT1 DACH1 DACH1 H9KXQ2_CALJA H9KXQ2_CALJA CDK4 CDK4 LIG4 LIG4 BRK1 BRK1 FOSL2 FOSL2 FGF10 FGF10 MED31-2 MED31-2 ENSCJAP00000054712 ENSCJAP00000054712 PDGFC PDGFC LZTS2 LZTS2 IGF1 IGF1 NUPR1 NUPR1 MED31 MED31 CDKN1A CDKN1A CDK6 CDK6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCJAP00000062228Uncharacterized protein. (268 aa)
BAXBCL2 associated X, apoptosis regulator. (193 aa)
HRASHRas proto-oncogene, GTPase. (209 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
EREGEpiregulin. (169 aa)
C1QL4Complement C1q-like protein 4. (238 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CD74CD74 molecule. (300 aa)
IFI30IFI30 lysosomal thiol reductase. (282 aa)
RNASEH2BUncharacterized protein. (353 aa)
CD248CD248 molecule. (851 aa)
ENSCJAP00000068516Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (355 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (868 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (759 aa)
NDUFS4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (175 aa)
ENSCJAP00000070085Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (125 aa)
ENSCJAP00000070637Protein kinase domain-containing protein. (103 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
PARP10Poly [ADP-ribose] polymerase. (1090 aa)
ENSCJAP00000073742CDC73_N domain-containing protein. (390 aa)
ENSCJAP00000074274Uncharacterized protein. (184 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)
ENSCJAP00000075173Uncharacterized protein. (340 aa)
CDC73Cell division cycle 73. (550 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (318 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
PEX2Peroxisomal biogenesis factor 2. (305 aa)
ZMIZ1Zinc finger MIZ-type containing 1. (1066 aa)
FBXO4F-box only protein 4 isoform 1. (387 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1204 aa)
SKISKI proto-oncogene. (729 aa)
FBRSFibrosin. (982 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
MORC3MORC family CW-type zinc finger 3. (939 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
CCNA2Cyclin-A2; Belongs to the cyclin family. (432 aa)
WAPLWAPL cohesin release factor. (1182 aa)
MED25Mediator complex subunit 25. (880 aa)
PDGFAPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (443 aa)
DHX9DExH-box helicase 9. (1286 aa)
PLA2G1BPhospholipase A(2). (148 aa)
S100A6Protein S100; Belongs to the S-100 family. (90 aa)
LIFLIF interleukin 6 family cytokine. (241 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
B4GALT7Beta-1,4-galactosyltransferase 7. (327 aa)
XRCC4DNA repair protein XRCC4 isoform 1. (334 aa)
EMDEmerin (Predicted). (258 aa)
FN1Fibronectin isoform 1 preproprotein. (2478 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa)
SPHK1DAGKc domain-containing protein. (469 aa)
NF1Neurofibromin 1. (2839 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
CTC1CST telomere replication complex component 1. (1217 aa)
CD300ACD300a molecule. (305 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6 isoform 1. (355 aa)
CCNB1G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (429 aa)
PMLPromyelocytic leukemia. (881 aa)
CTNNB1Catenin beta 1. (774 aa)
E2F1E2F transcription factor 1. (439 aa)
GAS6Growth arrest specific 6. (705 aa)
PAWRPRKC apoptosis WT1 regulator protein. (340 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
NLRC3NLR family CARD domain containing 3. (1065 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
DAB2IPDAB2 interacting protein. (1192 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
DACH1Dachshund family transcription factor 1. (753 aa)
H9KXQ2_CALJAUncharacterized protein. (115 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (302 aa)
LIG4DNA ligase. (911 aa)
BRK1Uncharacterized protein. (75 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
MED31-2Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
ENSCJAP00000054712Uncharacterized protein. (115 aa)
PDGFCPlatelet-derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (344 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
IGF1Insulin like growth factor 1. (197 aa)
NUPR1Nuclear protein 1 isoform b. (82 aa)
MED31Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (131 aa)
CDKN1ACyclin-dependent kinase inhibitor 1. (158 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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