(98 nodes) Oogenesis network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCDC155	Coiled-coil domain containing 155. (562 aa)
	AURKC	Aurora kinase C isoform 1; Belongs to the protein kinase superfamily. (309 aa)
	ENSCJAP00000078626	Uncharacterized protein. (158 aa)
	BHMG1	Basic helix-loop-helix and HMG-box containing 1. (708 aa)
	RPS6KA2	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (721 aa)
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (469 aa)
	ENSCJAP00000076601	Uncharacterized protein. (127 aa)
	ERCC1	Uncharacterized protein. (356 aa)
	TDRD6	Tudor domain containing 6. (2118 aa)
	ZNF830	Zinc finger protein 830. (371 aa)
	REC8	REC8 meiotic recombination protein. (528 aa)
	ENSCJAP00000074992	Uncharacterized protein. (116 aa)
	ZGLP1	Zinc finger GATA like protein 1. (293 aa)
	SRC	Tyrosine-protein kinase. (553 aa)
	ENSCJAP00000073490	Uncharacterized protein. (98 aa)
	TDRD15	Tudor domain containing 15. (1937 aa)
	MLH1	MutL homolog 1. (820 aa)
	ENSCJAP00000068998	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (231 aa)
	KMT2D	Uncharacterized protein. (743 aa)
	ENSCJAP00000067771	Uncharacterized protein. (78 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	BCL2	BCL2 apoptosis regulator. (240 aa)
	YTHDC1	YTH domain containing 1. (736 aa)
	NANOS1	Nanos C2HC-type zinc finger 1; Belongs to the nanos family. (413 aa)
	EREG	Epiregulin. (169 aa)
	PAQR5	Progestin and adipoQ receptor family member 5. (330 aa)
	TDRD10	Tudor domain containing 10. (365 aa)
	EDN1	Endothelin-1 isoform 1 preproprotein. (213 aa)
	INHBB	Inhibin subunit beta B. (407 aa)
	FOXL2	Forkhead box L2. (376 aa)
	ENSCJAP00000057591	CSD_1 domain-containing protein. (358 aa)
	ENSCJAP00000056467	Uncharacterized protein. (99 aa)
	ENSCJAP00000054854	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (218 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	NANOS2	Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (141 aa)
	PTN	Uncharacterized protein. (182 aa)
	ENSCJAP00000054380	annotation not available (98 aa)
	MARF1	Meiosis regulator and mRNA stability factor 1. (1741 aa)
	ENSCJAP00000053832	Uncharacterized protein. (81 aa)
	RPS6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
	MTHFSD	Methenyltetrahydrofolate synthase domain-containing protein isoform 4. (382 aa)
	PDE5A	Phosphodiesterase. (875 aa)
	FIGLA	Folliculogenesis specific bHLH transcription factor. (219 aa)
	HORMAD1	HORMA domain containing 1. (393 aa)
	WDR77	Methylosome protein 50. (342 aa)
	YTHDF2	YTH domain family protein 2 isoform 1. (579 aa)
	PDE3A	Phosphodiesterase. (1141 aa)
	MEIOC	Meiosis specific with coiled-coil domain. (954 aa)
	MEI4	Meiotic double-stranded break formation protein 4. (384 aa)
	F7HF06_CALJA	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (231 aa)
	PAQR7	Progestin and adipoQ receptor family member 7. (346 aa)
	TUT4	Terminal uridylyltransferase 4 isoform a. (1634 aa)
	CDC25B	Cell division cycle 25B. (588 aa)
	TAF4B	TATA-box binding protein associated factor 4b. (868 aa)
	F7IBT5_CALJA	Uncharacterized protein. (202 aa)
	NPM2	Nucleophosmin/nucleoplasmin 2. (256 aa)
	PIWIL2	Piwi like RNA-mediated gene silencing 2; Belongs to the argonaute family. (973 aa)
	PTK2B	Protein-tyrosine kinase 2-beta isoform a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
	TDRD1	Tudor domain containing 1. (1184 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (396 aa)
	C14orf39	Chromosome 14 open reading frame 39. (586 aa)
	BRCA2	BRCA2 DNA repair associated. (3409 aa)
	F6QPI3_CALJA	BHLH domain-containing protein. (425 aa)
	CTNNB1	Catenin beta 1. (774 aa)
	PABPC1L	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
	HEXB	Beta-hexosaminidase. (553 aa)
	YTHDC2	YTH domain containing 2. (1416 aa)
	F6Y5L6_CALJA	CSD_1 domain-containing protein. (358 aa)
	ZP3	ZP domain-containing protein. (424 aa)
	DIAPH2	Diaphanous related formin 2. (1101 aa)
	DDX20	DEAD-box helicase 20. (822 aa)
	AMH	Anti-Mullerian hormone. (559 aa)
	FBXO5	F-box protein 5. (444 aa)
	F7IMV6_CALJA	Uncharacterized protein. (146 aa)
	SEBOX	SEBOX homeobox. (188 aa)
	STRA8	Stimulated by retinoic acid 8. (330 aa)
	MDK	Midkine isoform a. (144 aa)
	DMC1	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (339 aa)
	PAQR8	Progestin and adipoQ receptor family member 8. (354 aa)
	DMRT1	Doublesex and mab-3 related transcription factor 1. (378 aa)
	SOHLH1	Spermatogenesis and oogenesis specific basic helix-loop-helix 1. (404 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
	NOBOX	NOBOX oogenesis homeobox. (657 aa)
	METTL3	N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (580 aa)
	TDRD5	Tudor domain containing 5. (1034 aa)
	TDRKH	Tudor and KH domain containing isoform a (Predicted). (560 aa)
	PLD6	Phospholipase D family member 6. (243 aa)
	BMPR1B	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
	PAQR6	Progestin and adipoQ receptor family member 6 isoform 2. (344 aa)
	PTX3	Pentraxin 3. (496 aa)
	NANOS3	Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (167 aa)
	CCDC36	Coiled-coil domain containing 36. (600 aa)
	TNFAIP6	Tumor necrosis factor-inducible gene 6 protein. (277 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1268 aa)
	EDNRA	Endothelin-1 receptor isoform a; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	TUT7	Terminal uridylyl transferase 7. (1490 aa)
	LGR5	Leucine-rich repeat-containing G-protein coupled receptor 5. (907 aa)
	GPR149	G protein-coupled receptor 149. (731 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMH	BMPR1B	ENSCJAP00000024259	ENSCJAP00000012950	Anti-Mullerian hormone.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.660
AMH	DMRT1	ENSCJAP00000024259	ENSCJAP00000019669	Anti-Mullerian hormone.	Doublesex and mab-3 related transcription factor 1.	0.746
AMH	FIGLA	ENSCJAP00000024259	ENSCJAP00000051634	Anti-Mullerian hormone.	Folliculogenesis specific bHLH transcription factor.	0.514
AMH	FOXL2	ENSCJAP00000024259	ENSCJAP00000057945	Anti-Mullerian hormone.	Forkhead box L2.	0.629
AMH	INHBB	ENSCJAP00000024259	ENSCJAP00000059558	Anti-Mullerian hormone.	Inhibin subunit beta B.	0.405
AMH	NANOS2	ENSCJAP00000024259	ENSCJAP00000054586	Anti-Mullerian hormone.	Nanos C2HC-type zinc finger 2; Belongs to the nanos family.	0.436
AMH	NOBOX	ENSCJAP00000024259	ENSCJAP00000018244	Anti-Mullerian hormone.	NOBOX oogenesis homeobox.	0.452
AMH	WNT4	ENSCJAP00000024259	ENSCJAP00000067759	Anti-Mullerian hormone.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.505
ATM	BCL2	ENSCJAP00000018844	ENSCJAP00000066653	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	BCL2 apoptosis regulator.	0.545
ATM	BRCA2	ENSCJAP00000018844	ENSCJAP00000034250	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	BRCA2 DNA repair associated.	0.966
ATM	CDC25B	ENSCJAP00000018844	ENSCJAP00000039482	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell division cycle 25B.	0.440
ATM	DMC1	ENSCJAP00000018844	ENSCJAP00000021648	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	0.721
ATM	ERCC1	ENSCJAP00000018844	ENSCJAP00000076581	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Uncharacterized protein.	0.756
ATM	HORMAD1	ENSCJAP00000018844	ENSCJAP00000050371	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	HORMA domain containing 1.	0.474
ATM	MLH1	ENSCJAP00000018844	ENSCJAP00000069380	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	MutL homolog 1.	0.894
ATM	SPO11	ENSCJAP00000018844	ENSCJAP00000035571	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	SPO11 initiator of meiotic double stranded breaks.	0.763
AURKC	TRIP13	ENSCJAP00000000030	ENSCJAP00000077693	Aurora kinase C isoform 1; Belongs to the protein kinase superfamily.	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family.	0.509
BCL2	ATM	ENSCJAP00000066653	ENSCJAP00000018844	BCL2 apoptosis regulator.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.545
BCL2	CTNNB1	ENSCJAP00000066653	ENSCJAP00000033154	BCL2 apoptosis regulator.	Catenin beta 1.	0.511
BCL2	DMRT1	ENSCJAP00000066653	ENSCJAP00000019669	BCL2 apoptosis regulator.	Doublesex and mab-3 related transcription factor 1.	0.448