STRINGSTRING
AGR2 AGR2 STAT5B STAT5B NOL12 NOL12 ENSCJAP00000078263 ENSCJAP00000078263 CYFIP1 CYFIP1 ENSCJAP00000076812 ENSCJAP00000076812 BBS2 BBS2 PLAA PLAA FGF9 FGF9 BDNF BDNF SYT3 SYT3 ENSCJAP00000073738 ENSCJAP00000073738 ANAPC2 ANAPC2 SLC6A3 SLC6A3 IGF2 IGF2 GHR GHR WNT3A WNT3A PRKN PRKN CPNE5 CPNE5 AKT1 AKT1 ENSCJAP00000070813 ENSCJAP00000070813 MKKS MKKS DLL1 DLL1 ERBB4 ERBB4 LPAR3 LPAR3 HEY2 HEY2 BCL11A BCL11A MAPK14 MAPK14 IL7 IL7 DISC1 DISC1 LIMK1 LIMK1 BCL2 BCL2 MEGF8 MEGF8 DSCAM DSCAM FGFR2 FGFR2 SYT17 SYT17 ENSCJAP00000064549 ENSCJAP00000064549 EFNA5 EFNA5 RNF157 RNF157 SMAD7 SMAD7 EDN1 EDN1 ARX ARX NTN1 NTN1 MEF2C MEF2C MUL1 MUL1 RND2 RND2 ENSCJAP00000057377 ENSCJAP00000057377 IGF1 IGF1 ENSCJAP00000056114 ENSCJAP00000056114 CDH4 CDH4 SMURF1 SMURF1 HOPX HOPX INSR INSR ENSCJAP00000052896 ENSCJAP00000052896 PLCB1 PLCB1 PPARD PPARD BMPR1A BMPR1A SEMA4D SEMA4D PROX1 PROX1 RPS6KB1 RPS6KB1 SASH3 SASH3 DBNL DBNL SEMA7A SEMA7A GOLGA4 GOLGA4 ADNP ADNP MYOD1 MYOD1 CREB1 CREB1 SOX15 SOX15 FOXS1 FOXS1 YBX3 YBX3 GHRH GHRH SLC23A2 SLC23A2 GATA6 GATA6 MAPT MAPT F7GME1_CALJA F7GME1_CALJA SHTN1 SHTN1 ATP8A2 ATP8A2 BMP10 BMP10 GPAM GPAM CACNG7 CACNG7 BBS4 BBS4 NIPBL NIPBL LEP LEP FGF8 FGF8 TSHR TSHR ZFYVE27 ZFYVE27 WNT3 WNT3 GHRL GHRL MAP1B MAP1B CXCL12 CXCL12 CPNE9 CPNE9 MAP3K13 MAP3K13 SPTBN4 SPTBN4 RUFY3 RUFY3 NRP1 NRP1 RASAL1 RASAL1 DRD2 DRD2 FN1 FN1 TBX20 TBX20 TRPV2 TRPV2 AGRN AGRN L1CAM L1CAM RAG2 RAG2 VIL1 VIL1 NOTCH1 NOTCH1 MACF1 MACF1 SMO SMO ACACB ACACB PARP2 PARP2 RIMS1 RIMS1 TBX5 TBX5 CHD7 CHD7 SEMA5A SEMA5A GHRHR GHRHR ITSN2 ITSN2 NRG1 NRG1 GLI1 GLI1 TRPC5 TRPC5 DBN1 DBN1 ZFPM2 ZFPM2 CRABP2 CRABP2 TWF2 TWF2 SYT2 SYT2 WT1 WT1 CDKL5 CDKL5 AKAP6 AKAP6 PIM1 PIM1 SRF SRF BMPR2 BMPR2 PEX5 PEX5 PPIB PPIB WNT2 WNT2 TGFBR2 TGFBR2 SYT4 SYT4 EZR EZR CSF1 CSF1 CAPN3 CAPN3 POU4F2 POU4F2 GHSR GHSR TGFBR3 TGFBR3 PLS1 PLS1 ACTN3 ACTN3 TBX2 TBX2 YAP1 YAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGR2Uncharacterized protein. (189 aa)
STAT5BSignal transducer and activator of transcription. (792 aa)
NOL12Uncharacterized protein. (279 aa)
ENSCJAP00000078263Uncharacterized protein. (523 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1296 aa)
ENSCJAP00000076812ERM domain-containing protein. (114 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (738 aa)
PLAAPhospholipase A-2-activating protein. (795 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (332 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (330 aa)
SYT3Synaptotagmin 3. (704 aa)
ENSCJAP00000073738HMG box domain-containing protein. (322 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (1386 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (587 aa)
IGF2Insulin like growth factor 2. (348 aa)
GHRGrowth hormone receptor. (643 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (476 aa)
CPNE5Copine 5. (621 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (459 aa)
ENSCJAP00000070813C2 domain-containing protein. (207 aa)
MKKSMcKusick-Kaufman syndrome. (591 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (761 aa)
ERBB4Receptor protein-tyrosine kinase. (1331 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (358 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (338 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (835 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa)
DISC1Disrupted in schizophrenia 1 protein isoform L. (851 aa)
LIMK1LIM domain kinase 1 isoform 1. (640 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
MEGF8Uncharacterized protein. (440 aa)
DSCAMDS cell adhesion molecule. (2010 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
SYT17Synaptotagmin-17. (474 aa)
ENSCJAP00000064549Uncharacterized protein. (118 aa)
EFNA5Ephrin-A5; Belongs to the ephrin family. (228 aa)
RNF157RING finger protein 157. (683 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
EDN1Endothelin-1 isoform 1 preproprotein. (213 aa)
ARXAristaless related homeobox. (562 aa)
NTN1Netrin-1. (604 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform 3. (483 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (527 aa)
RND2Rho-related GTP-binding protein RhoN. (227 aa)
ENSCJAP00000057377Regulating synaptic membrane exocytosis 2. (1367 aa)
IGF1Insulin like growth factor 1. (197 aa)
ENSCJAP00000056114Uncharacterized protein. (221 aa)
CDH4Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (916 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
HOPXHOP homeobox. (90 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
ENSCJAP00000052896Uncharacterized protein. (738 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform 1. (441 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SEMA4DSemaphorin-4D isoform 1; Belongs to the semaphorin family. (862 aa)
PROX1Prospero homeobox protein 1. (737 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
SASH3SAM and SH3 domain-containing protein 3. (380 aa)
DBNLDrebrin like. (438 aa)
SEMA7ASemaphorin-7A isoform 1 preproprotein; Belongs to the semaphorin family. (662 aa)
GOLGA4Golgin A4. (2232 aa)
ADNPActivity-dependent neuroprotector homeobox protein. (1103 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (348 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
SOX15SRY-box transcription factor 15. (233 aa)
FOXS1Forkhead box S1. (331 aa)
YBX3Y-box binding protein 3. (370 aa)
GHRHGrowth hormone releasing hormone. (107 aa)
SLC23A2Solute carrier family 23 member 2. (651 aa)
GATA6GATA binding protein 6. (592 aa)
MAPTMicrotubule-associated protein. (748 aa)
F7GME1_CALJAUncharacterized protein. (594 aa)
SHTN1Shootin 1. (631 aa)
ATP8A2Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (841 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
BBS4Bardet-Biedl syndrome 4. (518 aa)
NIPBLNipped-B protein. (2804 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (416 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
GHRLAppetite-regulating hormone isoform 1 preproprotein. (117 aa)
MAP1BMicrotubule associated protein 1B. (2465 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
CPNE9Copine family member 9. (553 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (987 aa)
SPTBN4Spectrin beta chain, non-erythrocytic 4 isoform sigma5. (678 aa)
RUFY3Protein RUFY3 isoform 1. (620 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (927 aa)
RASAL1RAS protein activator like 1. (806 aa)
DRD2D(2) dopamine receptor isoform long; Belongs to the G-protein coupled receptor 1 family. (443 aa)
FN1Fibronectin isoform 1 preproprotein. (2478 aa)
TBX20T-box transcription factor 20. (447 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (765 aa)
AGRNAgrin. (2045 aa)
L1CAML1 cell adhesion molecule. (1320 aa)
RAG2Recombination activating 2. (527 aa)
VIL1Villin 1. (827 aa)
NOTCH1Notch receptor 1. (2551 aa)
MACF1Microtubule actin crosslinking factor 1. (7595 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
PARP2Poly [ADP-ribose] polymerase. (570 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1691 aa)
TBX5T-box transcription factor TBX5 isoform 1. (518 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2994 aa)
SEMA5ASemaphorin 5A. (1074 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
ITSN2Intersectin 2. (1690 aa)
NRG1Neuregulin 1. (713 aa)
GLI1GLI family zinc finger 1. (1106 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
DBN1Drebrin 1. (696 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
CRABP2Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
TWF2Twinfilin actin binding protein 2. (349 aa)
SYT2Synaptotagmin 2. (424 aa)
WT1WT1 transcription factor. (522 aa)
CDKL5Cyclin dependent kinase like 5. (1030 aa)
AKAP6A-kinase anchoring protein 6. (2320 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
SRFSerum response factor. (509 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
PEX5TPR_REGION domain-containing protein. (660 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
SYT4Synaptotagmin-4. (425 aa)
EZREzrin. (591 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (549 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (820 aa)
POU4F2POU domain protein. (408 aa)
GHSRGhrelin receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform a. (851 aa)
PLS1Plastin-1. (629 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (942 aa)
TBX2T-box transcription factor 2. (713 aa)
YAP1Yes associated protein 1. (507 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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