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SIRT4 | NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa) | ||||
CASR | Calcium sensing receptor. (1089 aa) | ||||
KCNJ11 | ATP-sensitive inward rectifier potassium channel 11 isoform 1. (390 aa) | ||||
SYT7 | Uncharacterized protein. (879 aa) | ||||
PICK1 | Protein interacting with PRKCA 1. (448 aa) | ||||
VSNL1 | Visinin like 1. (257 aa) | ||||
EFNA5 | Ephrin-A5; Belongs to the ephrin family. (228 aa) | ||||
NNAT | Uncharacterized protein. (125 aa) | ||||
JAGN1 | Protein jagunal homolog 1. (183 aa) | ||||
NR1H4 | Nuclear receptor subfamily 1 group H member 4. (486 aa) | ||||
DOC2B | Double C2-like domain-containing protein. (412 aa) | ||||
TFAP2B | Transcription factor AP-2 beta. (569 aa) | ||||
ENSCJAP00000065650 | Transcription factor 7 like 2. (649 aa) | ||||
CDV3 | Protein CDV3 homolog isoform b. (258 aa) | ||||
TRH | Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (242 aa) | ||||
CDV3-2 | Uncharacterized protein. (209 aa) | ||||
NDUFAF2 | Uncharacterized protein. (108 aa) | ||||
CDK16 | Cyclin dependent kinase 16. (570 aa) | ||||
SOX4 | Transcription factor SOX. (472 aa) | ||||
PIM3 | Pim-3 proto-oncogene, serine/threonine kinase. (596 aa) | ||||
PPP3CA | Serine/threonine-protein phosphatase. (521 aa) | ||||
ENSCJAP00000068405 | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (210 aa) | ||||
CAPN10 | Calpain 10; Belongs to the peptidase C2 family. (783 aa) | ||||
FOXO1 | Fork-head domain-containing protein. (654 aa) | ||||
EIPR1 | EARP complex and GARP complex interacting protein 1. (387 aa) | ||||
SRI | Uncharacterized protein. (259 aa) | ||||
ALOX5 | Arachidonate 5-lipoxygenase. (737 aa) | ||||
KCNA5 | Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (602 aa) | ||||
ENSCJAP00000071063 | PFK domain-containing protein. (150 aa) | ||||
ENSCJAP00000071129 | Fork-head domain-containing protein. (540 aa) | ||||
PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (476 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1254 aa) | ||||
HMGN3 | High mobility group nucleosomal binding domain 3. (130 aa) | ||||
RBP4 | Retinol binding protein 4; Belongs to the calycin superfamily. Lipocalin family. (303 aa) | ||||
SLC8B1 | Solute carrier family 8 member B1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (600 aa) | ||||
CCL5 | C-C motif chemokine. (91 aa) | ||||
PER2 | Period circadian regulator 2. (1309 aa) | ||||
SYT9 | Synaptotagmin 9. (492 aa) | ||||
ENSCJAP00000073312 | Uncharacterized protein. (131 aa) | ||||
PDX1 | Homeobox domain-containing protein. (282 aa) | ||||
GPER1 | G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa) | ||||
PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 isoform 1. (223 aa) | ||||
ENSCJAP00000074997 | LSDAT_euk domain-containing protein. (136 aa) | ||||
ENSCJAP00000075133 | Uncharacterized protein. (332 aa) | ||||
STX4 | Syntaxin 4; Belongs to the syntaxin family. (414 aa) | ||||
ENSCJAP00000077629 | Uncharacterized protein. (150 aa) | ||||
F7GYC0_CALJA | Uncharacterized protein. (227 aa) | ||||
UCN3 | Urocortin-3 preproprotein. (161 aa) | ||||
ANO1 | Anoctamin. (538 aa) | ||||
GHSR | Ghrelin receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa) | ||||
BLK | Tyrosine-protein kinase. (464 aa) | ||||
REST | RE1 silencing transcription factor. (1076 aa) | ||||
ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa) | ||||
RFX6 | Regulatory factor X6. (928 aa) | ||||
SYTL4 | Synaptotagmin like 4. (670 aa) | ||||
CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1481 aa) | ||||
CCN3 | Cellular communication network factor 3. (357 aa) | ||||
FOXA2 | Forkhead box A2. (456 aa) | ||||
SLC30A8 | Solute carrier family 30 member 8. (369 aa) | ||||
GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (840 aa) | ||||
ENSA | Alpha-endosulfine isoform 3; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (121 aa) | ||||
ACSL4 | Acyl-CoA synthetase long chain family member 4. (799 aa) | ||||
MCU | Calcium uniporter protein, mitochondrial isoform 1. (350 aa) | ||||
ADCY5 | Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa) | ||||
GCK | Phosphotransferase. (478 aa) | ||||
GIPR | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa) | ||||
ABCC8 | ATP binding cassette subfamily C member 8. (1582 aa) | ||||
NR0B2 | Nuclear receptor subfamily 0 group B member 2. (257 aa) | ||||
ARNTL | Aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform a. (626 aa) | ||||
ISL1 | Insulin gene enhancer protein ISL-1. (349 aa) | ||||
SFRP1 | Secreted frizzled-related protein 1. (314 aa) | ||||
C1QTNF12 | C1q and TNF related 12. (298 aa) | ||||
STXBP4 | Syntaxin binding protein 4. (554 aa) | ||||
NEUROD1 | Neurogenic differentiation factor. (356 aa) | ||||
ABCA12 | ATP binding cassette subfamily A member 12. (2595 aa) | ||||
SLC25A22 | Solute carrier family 25 member 22; Belongs to the mitochondrial carrier (TC 2.A.29) family. (323 aa) | ||||
UQCC2 | Ubiquinol-cytochrome c reductase complex assembly factor 2. (126 aa) | ||||
PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (600 aa) | ||||
SIDT2 | SID1 transmembrane family member 2. (853 aa) | ||||
HNF1A | HNF1 homeobox A. (638 aa) | ||||
C2CD2L | C2CD2 like. (707 aa) | ||||
SIRT6 | NAD-dependent protein deacetylase sirtuin-6 isoform 1. (355 aa) | ||||
F7B7Z6_CALJA | Uncharacterized protein. (58 aa) | ||||
SLC9B2 | Solute carrier family 9 member B2. (537 aa) | ||||
LRP5 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa) | ||||
CPT1A | Carnitine O-palmitoyltransferase 1, liver isoform isoform 1; Belongs to the carnitine/choline acetyltransferase family. (773 aa) | ||||
HADH | Hydroxyacyl-CoA dehydrogenase. (407 aa) | ||||
NR1D1 | Nuclear receptor subfamily 1 group D member 1. (614 aa) | ||||
OSBP | Oxysterol-binding protein; Belongs to the OSBP family. (807 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) | ||||
NLGN2 | Neuroligin 2. (838 aa) | ||||
GHRL | Appetite-regulating hormone isoform 1 preproprotein. (117 aa) | ||||
MPC2 | Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (127 aa) | ||||
ABAT | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (542 aa) | ||||
PFKL | PFK domain-containing protein. (409 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) | ||||
HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) | ||||
BAD | Bcl2 antagonist of cell death. (167 aa) | ||||
CHGA | Chromogranin A. (457 aa) | ||||
CLOCK | Circadian locomoter output cycles protein kaput. (850 aa) | ||||
RPH3AL | Rabphilin 3A like (without C2 domains). (312 aa) | ||||
HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) | ||||
BIRC5 | Baculoviral IAP repeat-containing protein 5 isoform 1. (142 aa) | ||||
FAM3D | Family with sequence similarity 3 member D. (224 aa) | ||||
LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (810 aa) | ||||
GPR68 | G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa) | ||||
KCNB1 | Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa) | ||||
SREBF1 | Sterol regulatory element binding transcription factor 1. (1178 aa) | ||||
EPHA5 | Ephrin type-A receptor 5 isoform a. (1038 aa) | ||||
PLA2G6 | Uncharacterized protein. (836 aa) | ||||
GIP | Gastric inhibitory polypeptide. (153 aa) | ||||
RFX3 | Regulatory factor X3. (588 aa) | ||||
IL6 | Interleukin 6. (212 aa) | ||||
PCK2 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform 1. (640 aa) | ||||
ICA1 | AH domain-containing protein. (509 aa) | ||||
PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa) | ||||
KLF7 | Krueppel-like factor 7 isoform 1. (302 aa) | ||||
PPARD | Peroxisome proliferator-activated receptor delta isoform 1. (441 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (232 aa) | ||||
IRS2 | Insulin receptor substrate 2. (1327 aa) | ||||
MIDN | Midnolin. (714 aa) | ||||
FKBP1B | Peptidylprolyl isomerase. (111 aa) | ||||
CARTPT | Cocaine-and amphetamine-regulated transcript protein preproprotein. (116 aa) | ||||
IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) | ||||
ACVR1C | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (579 aa) | ||||
TUNAR | TCL1 upstream neural differentiation-associated RNA. (48 aa) | ||||
G6PC2 | Uncharacterized protein. (80 aa) | ||||
TRPM4 | Uncharacterized protein. (31 aa) | ||||
INHBB | Inhibin subunit beta B. (407 aa) | ||||
FFAR1 | Free fatty acid receptor 1. (300 aa) | ||||
TM7SF3 | Transmembrane 7 superfamily member 3. (570 aa) | ||||
STXBP5L | Syntaxin binding protein 5 like. (1156 aa) | ||||
PPP3CB | Serine/threonine-protein phosphatase. (525 aa) | ||||
SLC16A1 | Monocarboxylate transporter 1. (500 aa) |