(27 nodes) Mitogen-activated protein kinase binding network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCJAP00000076309	Angiotensin-converting enzyme. (703 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (442 aa)
	ENSCJAP00000078795	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (294 aa)
	NFATC1	Nuclear factor of activated T cells 1. (1218 aa)
	ENSCJAP00000063814	Uncharacterized protein. (581 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	GCH1	GTP cyclohydrolase 1 isoform 1. (250 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	MAPKAPK5	MAP kinase-activated protein kinase 5 isoform 2. (473 aa)
	ENSCJAP00000057718	Uncharacterized protein. (246 aa)
	SIRT1	Sirtuin 1. (753 aa)
	DUSP16	Dual specificity protein phosphatase 16. (661 aa)
	TNIP1	TNFAIP3-interacting protein 1 isoform 3. (636 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1306 aa)
	ACE	Angiotensin-converting enzyme. (1306 aa)
	DUSP2	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (314 aa)
	ATF7	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (494 aa)
	ARRB2	Beta-arrestin-2 isoform 1. (409 aa)
	MICAL2	Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1942 aa)
	STAU2	Double-stranded RNA-binding protein Staufen homolog 2 isoform a. (570 aa)
	DUSP10	Dual specificity protein phosphatase 10 isoform a; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
	TPR	Translocated promoter region, nuclear basket protein. (2363 aa)
	PRMT1	Protein arginine N-methyltransferase 1 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
	MAPK7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
	PPM1D	Protein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa)
	MAPKAPK2	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (439 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	MAPK14	ENSCJAP00000066744	ENSCJAP00000067408	Tyrosine-protein kinase.	Mitogen-activated protein kinase.	0.528
ABL1	MAPK7	ENSCJAP00000066744	ENSCJAP00000002248	Tyrosine-protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.443
ABL1	PPM1D	ENSCJAP00000066744	ENSCJAP00000002144	Tyrosine-protein kinase.	Protein phosphatase, Mg2+/Mn2+ dependent 1D.	0.465
ARRB2	MAPK7	ENSCJAP00000022453	ENSCJAP00000002248	Beta-arrestin-2 isoform 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.400
ATF7	MAPK14	ENSCJAP00000034756	ENSCJAP00000067408	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Mitogen-activated protein kinase.	0.855
ATF7	MAPK7	ENSCJAP00000034756	ENSCJAP00000002248	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.687
DUSP1	MAPK14	ENSCJAP00000070527	ENSCJAP00000067408	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.982
DUSP1	MAPK7	ENSCJAP00000070527	ENSCJAP00000002248	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.474
DUSP10	DUSP16	ENSCJAP00000011226	ENSCJAP00000040282	Dual specificity protein phosphatase 10 isoform a; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase 16.	0.451
DUSP10	MAPK14	ENSCJAP00000011226	ENSCJAP00000067408	Dual specificity protein phosphatase 10 isoform a; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.965
DUSP10	MAPK7	ENSCJAP00000011226	ENSCJAP00000002248	Dual specificity protein phosphatase 10 isoform a; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.556
DUSP16	DUSP10	ENSCJAP00000040282	ENSCJAP00000011226	Dual specificity protein phosphatase 16.	Dual specificity protein phosphatase 10 isoform a; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.451
DUSP16	MAPK14	ENSCJAP00000040282	ENSCJAP00000067408	Dual specificity protein phosphatase 16.	Mitogen-activated protein kinase.	0.878
DUSP16	MAPK7	ENSCJAP00000040282	ENSCJAP00000002248	Dual specificity protein phosphatase 16.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.556
DUSP2	MAPK14	ENSCJAP00000034829	ENSCJAP00000067408	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.821
DUSP2	MAPK7	ENSCJAP00000034829	ENSCJAP00000002248	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.474
MAPK14	ABL1	ENSCJAP00000067408	ENSCJAP00000066744	Mitogen-activated protein kinase.	Tyrosine-protein kinase.	0.528
MAPK14	ATF7	ENSCJAP00000067408	ENSCJAP00000034756	Mitogen-activated protein kinase.	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.	0.855
MAPK14	DUSP1	ENSCJAP00000067408	ENSCJAP00000070527	Mitogen-activated protein kinase.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.982
MAPK14	DUSP10	ENSCJAP00000067408	ENSCJAP00000011226	Mitogen-activated protein kinase.	Dual specificity protein phosphatase 10 isoform a; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.965