STRINGSTRING
CLUL1 CLUL1 TRAF5 TRAF5 PARK7 PARK7 H9KVK4_CALJA H9KVK4_CALJA STAT3 STAT3 FZD4 FZD4 TRIM62 TRIM62 FOSL1 FOSL1 SMAD3 SMAD3 PRKCZ PRKCZ PPP2R5B PPP2R5B CAPN3 CAPN3 CD36 CD36 TNFRSF11A TNFRSF11A CARD14 CARD14 LAMTOR5 LAMTOR5 AR AR EDA2R EDA2R NEUROG2 NEUROG2 EIF2AK2 EIF2AK2 TRAPPC9 TRAPPC9 ADCY8 ADCY8 RWDD1 RWDD1 COPS5 COPS5 TCF3 TCF3 MYOCD MYOCD EP300 EP300 BTK BTK DHX9 DHX9 WNT2 WNT2 MTDH MTDH ADAM8 ADAM8 SRF SRF KDM1A KDM1A S100A8 S100A8 S100A12 S100A12 TLR9 TLR9 PRKD1 PRKD1 SMARCA4 SMARCA4 AIM2 AIM2 RIPK3 RIPK3 PINK1 PINK1 TSSK4 TSSK4 RNF31 RNF31 CRTC1 CRTC1 WNT5A WNT5A DDX58 DDX58 ARHGEF2 ARHGEF2 IKBKB IKBKB F7I4B4_CALJA F7I4B4_CALJA ATF2 ATF2 IL18R1 IL18R1 HCLS1 HCLS1 NOD1 NOD1 PLA2G1B PLA2G1B TRIM13 TRIM13 ALK ALK TIRAP TIRAP HDAC4 HDAC4 CAMK1D CAMK1D CARD16 CARD16 CRTC3 CRTC3 ARHGEF5 ARHGEF5 MYD88 MYD88 SMO SMO SMARCB1 SMARCB1 TRIML1 TRIML1 CARD9 CARD9 NDP NDP TRIM38 TRIM38 TRAF6 TRAF6 H9KWS6_CALJA H9KWS6_CALJA ADCY1 ADCY1 RIPK4 RIPK4 DHX33 DHX33 NEUROD1 NEUROD1 NLRP3 NLRP3 PIDD1 PIDD1 CYTL1 CYTL1 JUP JUP FANK1 FANK1 TRIM27 TRIM27 IL18 IL18 RELN RELN IL5 IL5 AMH AMH HIPK2 HIPK2 SPHK1 SPHK1 TRIM25 TRIM25 APP APP TERF2IP TERF2IP IL1RAP IL1RAP IRAK1 IRAK1 IRAK3 IRAK3 ANKRD42 ANKRD42 MAP3K13 MAP3K13 ANXA3 ANXA3 ZBTB7A ZBTB7A RPS3 RPS3 TRIM21 TRIM21 TRIM68 TRIM68 BUD31 BUD31 PLPP3 PLPP3 FER FER NODAL NODAL IL1B IL1B TRADD TRADD ROR1 ROR1 DVL2 DVL2 IKBKG IKBKG STING1 STING1 CHUK CHUK F7GL96_CALJA F7GL96_CALJA TNFSF11 TNFSF11 RIPK1 RIPK1 RPS6KA5 RPS6KA5 CTH CTH CTNNB1 CTNNB1 RPS6KA4 RPS6KA4 TRIM8 TRIM8 CLOCK CLOCK IL10 IL10 NPM1 NPM1 ESR1 ESR1 ESR2 ESR2 CLU CLU JMY JMY FLOT1 FLOT1 TRIM6 TRIM6 TGFB1 TGFB1 SHH SHH SLCO3A1 SLCO3A1 PRKCQ PRKCQ TRIM26 TRIM26 TRIM15 TRIM15 WNT10B WNT10B WNT1 WNT1 RBCK1 RBCK1 RHEBL1 RHEBL1 ZIC2 ZIC2 DDRGK1 DDRGK1 PPARGC1B PPARGC1B ENSCJAP00000039892 ENSCJAP00000039892 DDIT3 DDIT3 TRIM37 TRIM37 EPHA5 EPHA5 TP53BP1 TP53BP1 AGER AGER SAV1 SAV1 IL6 IL6 TRAF1 TRAF1 CEBPG CEBPG NFAM1 NFAM1 RNF25 RNF25 LRP8 LRP8 PPARGC1A PPARGC1A IL18RAP IL18RAP OPRD1 OPRD1 NEUROD2 NEUROD2 TNF TNF PSMA6 PSMA6 ERC1 ERC1 ENSCJAP00000053979 ENSCJAP00000053979 LRP6 LRP6 STK3 STK3 KIT KIT PTEN PTEN CD40 CD40 ENSCJAP00000054920 ENSCJAP00000054920 NTS NTS PRKCI PRKCI TAF12 TAF12 CD40LG CD40LG ENSCJAP00000056948 ENSCJAP00000056948 EDA EDA NEUROG1 NEUROG1 SP100 SP100 MBTPS2 MBTPS2 ENSCJAP00000059748 ENSCJAP00000059748 ENSCJAP00000060287 ENSCJAP00000060287 TRIML2 TRIML2 FOXA1 FOXA1 TNFSF18 TNFSF18 PRKD2 PRKD2 ABRA ABRA EDN1 EDN1 PPRC1 PPRC1 FLOT2 FLOT2 NTSR1 NTSR1 CIB1 CIB1 NOD2 NOD2 ENSCJAP00000064549 ENSCJAP00000064549 RIPK2 RIPK2 ADGRF1 ADGRF1 ENSCJAP00000065208 ENSCJAP00000065208 MID2 MID2 RNF220 RNF220 FZD2 FZD2 ENSCJAP00000066598 ENSCJAP00000066598 TRIM41 TRIM41 MALT1 MALT1 NKX3-1 NKX3-1 TFRC TFRC PPP3CA PPP3CA ENSCJAP00000068210 ENSCJAP00000068210 CX3CL1 CX3CL1 TRIM32 TRIM32 DDR2 DDR2 NFAM1-2 NFAM1-2 PRKCB PRKCB STK36 STK36 ENSCJAP00000070453 ENSCJAP00000070453 LTF LTF AKT1 AKT1 MTPN MTPN PLCG2 PLCG2 NTRK1 NTRK1 WNT3A WNT3A ENSCJAP00000072004 ENSCJAP00000072004 LOC100411779 LOC100411779 S100A9 S100A9 ENSCJAP00000073449 ENSCJAP00000073449 ENSCJAP00000073487 ENSCJAP00000073487 ZC4H2 ZC4H2 BMP2 BMP2 TRIM22 TRIM22 RTKN2 RTKN2 RELA RELA TRAF2 TRAF2 CDKN2A CDKN2A ENSCJAP00000075173 ENSCJAP00000075173 TRIM14 TRIM14 IKBKE IKBKE RGCC RGCC ITGB2 ITGB2 BCL10 BCL10 TLR3 TLR3 IRAK2 IRAK2 ENSCJAP00000077152 ENSCJAP00000077152 RAB7B RAB7B ENSCJAP00000077433 ENSCJAP00000077433 ARID5B ARID5B ENSCJAP00000078157 ENSCJAP00000078157 ENSCJAP00000078307 ENSCJAP00000078307 CARD11 CARD11 CRNN CRNN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLUL1Clusterin; Belongs to the clusterin family. (494 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (574 aa)
PARK7Protein DJ-1. (189 aa)
H9KVK4_CALJAUncharacterized protein. (187 aa)
STAT3Signal transducer and activator of transcription. (771 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
TRIM62Tripartite motif-containing protein 62. (475 aa)
FOSL1FOS like 1, AP-1 transcription factor subunit. (271 aa)
SMAD3Mothers against decapentaplegic homolog. (437 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (646 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (820 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
TNFRSF11ATNF receptor superfamily member 11a. (616 aa)
CARD14Caspase recruitment domain family member 14. (1135 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (166 aa)
ARAndrogen receptor. (887 aa)
EDA2RUncharacterized protein. (317 aa)
NEUROG2Neurogenin 2. (272 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (552 aa)
TRAPPC9Trafficking protein particle complex 9. (1148 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
RWDD1RWD domain-containing protein 1 isoform a. (243 aa)
COPS5COP9 signalosome complex subunit 5. (334 aa)
TCF3Transcription factor 3. (677 aa)
MYOCDMyocardin isoform 1. (982 aa)
EP300E1A binding protein p300. (2426 aa)
BTKTyrosine-protein kinase. (659 aa)
DHX9DExH-box helicase 9. (1286 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
MTDHProtein LYRIC. (583 aa)
ADAM8ADAM metallopeptidase domain 8. (825 aa)
SRFSerum response factor. (509 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa)
TLR9TIR domain-containing protein. (1032 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (920 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1669 aa)
AIM2Absent in melanoma 2. (351 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (475 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (581 aa)
TSSK4Testis specific serine kinase 4. (339 aa)
RNF31E3 ubiquitin-protein ligase RNF31. (1072 aa)
CRTC1CREB-regulated transcription coactivator 1 isoform 3. (650 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
DDX58Putative ATP-dependent RNA helicase DDX58. (925 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (1031 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform 1. (756 aa)
F7I4B4_CALJAUncharacterized protein. (85 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
IL18R1Interleukin-18 receptor 1. (539 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (473 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
PLA2G1BPhospholipase A(2). (148 aa)
TRIM13Tripartite motif containing 13. (409 aa)
ALKTyrosine-protein kinase receptor. (1621 aa)
TIRAPToll/interleukin-1 receptor domain-containing adapter protein isoform a. (221 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1035 aa)
CAMK1DCalcium/calmodulin-dependent protein kinase type 1D isoform 2; Belongs to the protein kinase superfamily. (385 aa)
CARD16Caspase recruitment domain family member 16. (195 aa)
CRTC3CREB-regulated transcription coactivator 3 isoform a. (619 aa)
ARHGEF5Rho guanine nucleotide exchange factor 5. (1596 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (409 aa)
TRIML1Tripartite motif family like 1. (474 aa)
CARD9Caspase recruitment domain-containing protein 9 isoform 1. (537 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
TRIM38Tripartite motif-containing protein 38. (465 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (537 aa)
H9KWS6_CALJAMPN domain-containing protein. (339 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1003 aa)
RIPK4Receptor interacting serine/threonine kinase 4. (782 aa)
DHX33Putative ATP-dependent RNA helicase DHX33 isoform 1. (707 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
NLRP3NLR family pyrin domain containing 3. (1034 aa)
PIDD1P53-induced death domain protein 1. (910 aa)
CYTL1Cytokine like 1. (131 aa)
JUPJunction plakoglobin. (745 aa)
FANK1Fibronectin type 3 and ankyrin repeat domains protein 1. (345 aa)
TRIM27Tripartite motif containing 27. (513 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
RELNReelin. (3460 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
AMHAnti-Mullerian hormone. (559 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform 1. (1196 aa)
SPHK1DAGKc domain-containing protein. (469 aa)
TRIM25Tripartite motif containing 25. (624 aa)
APPAmyloid beta A4 protein isoform a. (770 aa)
TERF2IPTelomeric repeat-binding factor 2-interacting protein 1. (399 aa)
IL1RAPInterleukin-1 receptor accessory protein isoform 3. (687 aa)
IRAK1Interleukin-1 receptor-associated kinase 1 isoform 1 (Predicted). (712 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (710 aa)
ANKRD42Ankyrin repeat domain 42. (518 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (987 aa)
ANXA3Annexin. (323 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (282 aa)
TRIM21E3 ubiquitin-protein ligase TRIM21. (475 aa)
TRIM68E3 ubiquitin-protein ligase TRIM68. (485 aa)
BUD31BUD31 homolog. (144 aa)
PLPP3Lipid phosphate phosphohydrolase 3. (311 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
NODALNodal growth differentiation factor. (346 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (312 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (736 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (452 aa)
STING1Transmembrane protein 173. (377 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (754 aa)
F7GL96_CALJAUncharacterized protein. (195 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (670 aa)
RPS6KA5Ribosomal protein S6 kinase. (802 aa)
CTHCystathionine gamma-lyase isoform 1. (405 aa)
CTNNB1Catenin beta 1. (774 aa)
RPS6KA4Ribosomal protein S6 kinase. (772 aa)
TRIM8Putative E3 ubiquitin-protein ligase TRIM8. (551 aa)
CLOCKCircadian locomoter output cycles protein kaput. (850 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
NPM1Nucleophosmin isoform 1. (296 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
ESR2Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation. (530 aa)
CLUClusterin. (560 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (988 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (454 aa)
TRIM6Tripartite motif-containing 6 isoform 2 (Predicted). (488 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
SLCO3A1Solute carrier organic anion transporter family member. (710 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
TRIM26Tripartite motif-containing protein 26. (539 aa)
TRIM15Tripartite motif containing 15. (465 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (610 aa)
RHEBL1GTPase RhebL1. (183 aa)
ZIC2Zic family member 2. (532 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
PPARGC1BPeroxisome proliferator-activated receptor gamma coactivator 1-beta isoform 1. (1023 aa)
ENSCJAP00000039892Heat shock transcription factor 1. (557 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
TRIM37Tripartite motif containing 37. (930 aa)
EPHA5Ephrin type-A receptor 5 isoform a. (1038 aa)
TP53BP1Tumor protein p53 binding protein 1. (1971 aa)
AGERAdvanced glycosylation end-product specific receptor. (419 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
IL6Interleukin 6. (212 aa)
TRAF1TNF receptor-associated factor. (467 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
NFAM1NFAT activating protein with ITAM motif 1. (269 aa)
RNF25E3 ubiquitin-protein ligase RNF25. (457 aa)
LRP8LDL receptor related protein 8. (974 aa)
PPARGC1APPARG coactivator 1 alpha. (802 aa)
IL18RAPInterleukin 18 receptor accessory protein. (576 aa)
OPRD1Delta-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (372 aa)
NEUROD2Neurogenic differentiation factor. (380 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (232 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
ENSCJAP00000053979Nucleoplasmin domain-containing protein. (270 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
STK3Serine/threonine-protein kinase 3 isoform 1. (491 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (976 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
CD40Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). (274 aa)
ENSCJAP00000054920Uncharacterized protein. (287 aa)
NTSNeurotensin/neuromedin N preproprotein. (170 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
TAF12Transcription initiation factor TFIID subunit 12. (161 aa)
CD40LGCD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...] (261 aa)
ENSCJAP00000056948Uncharacterized protein. (287 aa)
EDATNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (389 aa)
NEUROG1BHLH domain-containing protein. (129 aa)
SP100SP100 nuclear antigen. (880 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (513 aa)
ENSCJAP00000059748DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (195 aa)
ENSCJAP00000060287DJ-1_PfpI domain-containing protein. (143 aa)
TRIML2Tripartite motif family like 2. (438 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (467 aa)
TNFSF18Tumor necrosis factor ligand 2A. (256 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (888 aa)
ABRAActin-binding Rho-activating protein. (377 aa)
EDN1Endothelin-1 isoform 1 preproprotein. (213 aa)
PPRC1PPARG related coactivator 1. (1661 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (483 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (609 aa)
CIB1Calcium and integrin binding 1. (230 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1013 aa)
ENSCJAP00000064549Uncharacterized protein. (118 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
ADGRF1Adhesion G protein-coupled receptor F1; Belongs to the G-protein coupled receptor 2 family. (952 aa)
ENSCJAP00000065208DJ-1_PfpI domain-containing protein. (153 aa)
MID2Putative E3 ubiquitin-protein ligase MID2 isoform 1. (735 aa)
RNF220E3 ubiquitin-protein ligase RNF220. (566 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
ENSCJAP00000066598Uncharacterized protein. (70 aa)
TRIM41Tripartite motif containing 41. (639 aa)
MALT1MALT1 paracaspase. (824 aa)
NKX3-1NK3 homeobox 1. (286 aa)
TFRCTransferrin receptor protein 1. (760 aa)
PPP3CASerine/threonine-protein phosphatase. (521 aa)
ENSCJAP00000068210Uncharacterized protein. (404 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (429 aa)
TRIM32E3 ubiquitin-protein ligase TRIM32. (653 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (868 aa)
NFAM1-2Uncharacterized protein. (184 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
STK36Serine/threonine kinase 36. (1315 aa)
ENSCJAP00000070453Uncharacterized protein. (466 aa)
LTFLactotransferrin; Belongs to the transferrin family. (710 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (459 aa)
MTPNMyotrophin. (118 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1288 aa)
NTRK1Tyrosine-protein kinase receptor. (795 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ENSCJAP00000072004Uncharacterized protein. (90 aa)
LOC100411779Uncharacterized protein. (230 aa)
S100A9S100 calcium binding protein A9; Belongs to the S-100 family. (125 aa)
ENSCJAP00000073449DJ-1_PfpI domain-containing protein. (83 aa)
ENSCJAP00000073487Uncharacterized protein. (364 aa)
ZC4H2Uncharacterized protein. (255 aa)
BMP2Bone morphogenetic protein 2. (401 aa)
TRIM22Tripartite motif containing 22. (533 aa)
RTKN2Rhotekin 2. (609 aa)
RELARELA proto-oncogene, NF-kB subunit. (571 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
CDKN2AUncharacterized protein. (273 aa)
ENSCJAP00000075173Uncharacterized protein. (340 aa)
TRIM14Tripartite motif-containing protein 14. (442 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (729 aa)
RGCCRegulator of cell cycle. (161 aa)
ITGB2Integrin beta. (866 aa)
BCL10B-cell lymphoma/leukemia 10. (233 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (640 aa)
ENSCJAP00000077152RWD domain-containing protein. (130 aa)
RAB7BUncharacterized protein. (382 aa)
ENSCJAP00000077433Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (136 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
ENSCJAP00000078157DJ-1_PfpI domain-containing protein. (148 aa)
ENSCJAP00000078307CREB regulated transcription coactivator 2. (702 aa)
CARD11Caspase recruitment domain-containing protein 11. (1154 aa)
CRNNCornulin. (614 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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