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| | STAU2 | Double-stranded RNA-binding protein Staufen homolog 2 isoform a. (570 aa) |
| | PLXNA4 | Plexin A4. (1894 aa) |
| | GRM5 | Metabotropic glutamate receptor 5 isoform a. (1210 aa) |
| | MME | Membrane metalloendopeptidase. (750 aa) |
| | DHX36 | DEAH-box helicase 36. (1036 aa) |
| | DLG5 | Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family. (1920 aa) |
| | CAPRIN2 | Caprin family member 2. (1070 aa) |
| | UFL1 | UFM1 specific ligase 1. (791 aa) |
| | RNF112 | RING finger protein 112. (631 aa) |
| | SERPINF1 | Serpin family F member 1; Belongs to the serpin family. (420 aa) |
| | IL6ST | Interleukin-6 receptor subunit beta isoform 1. (915 aa) |
| | NLGN1 | Neuroligin-1. (823 aa) |
| | FAIM | Fas apoptotic inhibitory molecule 1 isoform b. (201 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | ELL3 | Elongation factor RNA polymerase II-like 3 (Predicted). (398 aa) |
| | SOX8 | SRY-box transcription factor 8. (538 aa) |
| | EPHB1 | EPH receptor B1. (1055 aa) |
| | SLITRK3 | SLIT and NTRK like family member 3. (979 aa) |
| | PLXNC1 | Plexin C1. (1567 aa) |
| | SLITRK6 | SLIT and NTRK like family member 6. (840 aa) |
| | SLITRK5 | SLIT and NTRK like family member 5. (957 aa) |
| | BAIAP2 | BAI1 associated protein 2. (587 aa) |
| | DCT | Dopachrome tautomerase. (519 aa) |
| | PLXNB2 | Plexin-B2. (1839 aa) |
| | PLXNA2 | Plexin A2. (1885 aa) |
| | ADGRB3 | Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa) |
| | CUL7 | Cullin 7; Belongs to the cullin family. (1777 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | SRF | Serum response factor. (509 aa) |
| | NKX6-1 | NK6 homeobox 1. (366 aa) |
| | TTBK1 | Tau tubulin kinase 1. (1320 aa) |
| | PLXND1 | Plexin D1. (1808 aa) |
| | SEMA4A | Semaphorin-4A isoform 1; Belongs to the semaphorin family. (761 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) |
| | EPHB2 | EPH receptor B2. (987 aa) |
| | CDKL5 | Cyclin dependent kinase like 5. (1030 aa) |
| | TWF2 | Twinfilin actin binding protein 2. (349 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (666 aa) |
| | STK25 | Serine/threonine-protein kinase 25 isoform 1. (426 aa) |
| | CRABP2 | Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa) |
| | FOXG1 | Forkhead box G1. (505 aa) |
| | LRP2 | LDL receptor related protein 2. (4656 aa) |
| | DBN1 | Drebrin 1. (696 aa) |
| | GRID2 | Glutamate ionotropic receptor delta type subunit 2. (1007 aa) |
| | NIN | Ninein. (2134 aa) |
| | RGS14 | Regulator of G protein signaling 14. (567 aa) |
| | TRPC5 | Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa) |
| | IL1RAPL1 | Interleukin 1 receptor accessory protein like 1. (696 aa) |
| | GLI3 | GLI family zinc finger 3. (1578 aa) |
| | VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (402 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (232 aa) |
| | CLSTN1 | Calsyntenin-1 isoform 1. (981 aa) |
| | ROBO1 | Roundabout guidance receptor 1. (1654 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) |
| | LRRTM2 | Leucine-rich repeat transmembrane neuronal protein 2. (516 aa) |
| | ADGRB1 | Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1508 aa) |
| | SLITRK4 | SLIT and NTRK like family member 4. (837 aa) |
| | DICER1 | Endoribonuclease Dicer isoform 1; Belongs to the helicase family. Dicer subfamily. (1922 aa) |
| | LRP8 | LDL receptor related protein 8. (974 aa) |
| | F7GTI5_CALJA | Uncharacterized protein. (599 aa) |
| | F7FS90_CALJA | Uncharacterized protein. (314 aa) |
| | F7BYU4_CALJA | Uncharacterized protein. (216 aa) |
| | SEMA4D | Semaphorin-4D isoform 1; Belongs to the semaphorin family. (862 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | ASCL1 | Achaete-scute family bHLH transcription factor 1. (232 aa) |
| | DBNL | Drebrin like. (438 aa) |
| | SEMA7A | Semaphorin-7A isoform 1 preproprotein; Belongs to the semaphorin family. (662 aa) |
| | GOLGA4 | Golgin A4. (2232 aa) |
| | IL6 | Interleukin 6. (212 aa) |
| | GJC2 | Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (439 aa) |
| | NR2E1 | Nuclear receptor subfamily 2 group E member 1. (421 aa) |
| | ADNP | Activity-dependent neuroprotector homeobox protein. (1103 aa) |
| | SPEN | Spen family transcriptional repressor. (3659 aa) |
| | OBSL1 | Obscurin like 1. (1896 aa) |
| | SYNJ1 | Synaptojanin 1. (1610 aa) |
| | IL34 | Interleukin 34. (242 aa) |
| | LINGO4 | Leucine rich repeat and Ig domain containing 4. (593 aa) |
| | F7FT97_CALJA | Homeobox domain-containing protein. (286 aa) |
| | LINGO2 | Leucine rich repeat and Ig domain containing 2. (606 aa) |
| | SLITRK1 | SLIT and NTRK like family member 1. (696 aa) |
| | TGM2 | Transglutaminase 2. (687 aa) |
| | LRRC24 | Leucine rich repeat containing 24. (510 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | NEFL | Neurofilament light polypeptide; Belongs to the intermediate filament family. (543 aa) |
| | MAPT | Microtubule-associated protein. (748 aa) |
| | OTP | Homeobox protein orthopedia. (325 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (600 aa) |
| | SHTN1 | Shootin 1. (631 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (850 aa) |
| | PARP6 | Poly [ADP-ribose] polymerase. (630 aa) |
| | GSX2 | GS homeobox 2. (305 aa) |
| | E2F1 | E2F transcription factor 1. (439 aa) |
| | ANKRD27 | Ankyrin repeat domain 27. (1078 aa) |
| | SS18L2 | SS18-like protein 2. (77 aa) |
| | NPTN | Neuroplastin isoform b. (398 aa) |
| | CTNNB1 | Catenin beta 1. (774 aa) |
| | PTPRZ1 | Protein tyrosine phosphatase receptor type Z1. (2279 aa) |
| | ZNF335 | Zinc finger protein 335. (1345 aa) |
| | SNW1 | SNW domain-containing protein 1. (536 aa) |
| | WNT7A | Protein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa) |
| | PLXNA3 | Plexin A3. (1870 aa) |
| | ZFYVE27 | Zinc finger FYVE-type containing 27. (416 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa) |
| | LYN | Tyrosine-protein kinase. (491 aa) |
| | PLAG1 | PLAG1 zinc finger. (500 aa) |
| | PRPF19 | Pre-mRNA-processing factor 19. (504 aa) |
| | GHRL | Appetite-regulating hormone isoform 1 preproprotein. (117 aa) |
| | NLGN2 | Neuroligin 2. (838 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) |
| | MAP1B | Microtubule associated protein 1B. (2465 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa) |
| | LOC100410496 | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa) |
| | MAN2A1 | Alpha-mannosidase. (1144 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (681 aa) |
| | MAP6 | Microtubule associated protein 6. (825 aa) |
| | SRRT | Serrate RNA effector molecule homolog isoform a. (875 aa) |
| | MAP3K13 | Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (987 aa) |
| | NUMBL | NUMB like endocytic adaptor protein. (595 aa) |
| | LRRTM3 | Leucine-rich repeat transmembrane neuronal protein 3. (581 aa) |
| | TENM4 | Teneurin transmembrane protein 4. (2769 aa) |
| | RUFY3 | Protein RUFY3 isoform 1. (620 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (497 aa) |
| | NUMB | NUMB endocytic adaptor protein. (651 aa) |
| | IL1RAP | Interleukin-1 receptor accessory protein isoform 3. (687 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (927 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (462 aa) |
| | NTRK2 | Tyrosine-protein kinase receptor. (838 aa) |
| | SLIT2 | Slit guidance ligand 2. (1527 aa) |
| | F7IMV6_CALJA | Uncharacterized protein. (146 aa) |
| | OPRM1 | Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (473 aa) |
| | RELN | Reelin. (3460 aa) |
| | CBLN1 | Cerebellin 1 precursor. (193 aa) |
| | TIAM2 | T cell lymphoma invasion and metastasis 2. (1724 aa) |
| | SERPINE2 | Serpin family E member 2; Belongs to the serpin family. (409 aa) |
| | DRD2 | D(2) dopamine receptor isoform long; Belongs to the G-protein coupled receptor 1 family. (443 aa) |
| | SLITRK2 | SLIT and NTRK like family member 2. (845 aa) |
| | FN1 | Fibronectin isoform 1 preproprotein. (2478 aa) |
| | EPHA4 | Ephrin type-A receptor 4. (986 aa) |
| | TRPV2 | Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (765 aa) |
| | MDK | Midkine isoform a. (144 aa) |
| | CUX2 | Homeobox protein cut-like. (1484 aa) |
| | AGRN | Agrin. (2045 aa) |
| | XRCC4 | DNA repair protein XRCC4 isoform 1. (334 aa) |
| | L1CAM | L1 cell adhesion molecule. (1320 aa) |
| | NOTCH1 | Notch receptor 1. (2551 aa) |
| | DIXDC1 | DIX domain containing 1. (683 aa) |
| | MACF1 | Microtubule actin crosslinking factor 1. (7595 aa) |
| | CAPRIN1 | Cell cycle associated protein 1. (709 aa) |
| | LAYN | Layilin. (381 aa) |
| | F6SK74_CALJA | Uncharacterized protein. (593 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa) |
| | LIF | LIF interleukin 6 family cytokine. (241 aa) |
| | NKX6-2 | NK6 homeobox 2. (278 aa) |
| | KHDC3L | KHDC3-like protein. (228 aa) |
| | WDR62 | WD repeat-containing protein 62 isoform 1. (1525 aa) |
| | FBXW8 | F-box/WD repeat-containing protein 8 isoform 1. (598 aa) |
| | EEF2K | Eukaryotic elongation factor 2 kinase. (723 aa) |
| | SEMA5A | Semaphorin 5A. (1074 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1556 aa) |
| | ENSCJAP00000053892 | BAR domain-containing protein. (420 aa) |
| | PTN | Uncharacterized protein. (182 aa) |
| | ROBO2 | Roundabout guidance receptor 2. (1439 aa) |
| | ZNF365 | Zinc finger protein 365. (436 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | CDH4 | Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (916 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) |
| | CBLN2 | Cerebellin 2 precursor. (224 aa) |
| | MAG | Myelin associated glycoprotein. (637 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa) |
| | LRRTM4 | Leucine rich repeat transmembrane neuronal 4. (591 aa) |
| | RND2 | Rho-related GTP-binding protein RhoN. (227 aa) |
| | DMRTA2 | DMRT like family A2. (536 aa) |
| | PAX6 | Paired box 6. (472 aa) |
| | OLIG2 | Oligodendrocyte lineage transcription factor 2 (Predicted). (323 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (635 aa) |
| | NTN1 | Netrin-1. (604 aa) |
| | BRAF | Uncharacterized protein. (805 aa) |
| | KALRN | Kalirin RhoGEF kinase. (2986 aa) |
| | JADE2 | Jade family PHD finger 2. (835 aa) |
| | ID4 | Inhibitor of DNA binding 4, HLH protein. (161 aa) |
| | NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (292 aa) |
| | FLRT2 | Fibronectin leucine rich transmembrane protein 2. (660 aa) |
| | ENSCJAP00000063814 | Uncharacterized protein. (581 aa) |
| | THBS2 | Thrombospondin 2. (1255 aa) |
| | NRXN1 | Neurexin 1. (1507 aa) |
| | ITPKA | Kinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa) |
| | EFNA5 | Ephrin-A5; Belongs to the ephrin family. (228 aa) |
| | SHOX2 | Short stature homeobox 2. (319 aa) |
| | PTPRD | Receptor-type tyrosine-protein phosphatase delta isoform 1. (1916 aa) |
| | ENSCJAP00000065030 | Plexin_cytopl domain-containing protein. (55 aa) |
| | CLCF1 | Cardiotrophin-like cytokine factor 1 isoform 1. (225 aa) |
| | XRCC2 | DNA repair protein XRCC2. (280 aa) |
| | SOX11 | Transcription factor SOX. (448 aa) |
| | GFAP | Glial fibrillary acidic protein; Belongs to the intermediate filament family. (504 aa) |
| | DSCAM | DS cell adhesion molecule. (2010 aa) |
| | MEGF8 | Uncharacterized protein. (440 aa) |
| | LRTM2 | Leucine-rich repeat and transmembrane domain-containing protein 2. (370 aa) |
| | BHLHB9 | Protein BHLHb9. (547 aa) |
| | LIMK1 | LIM domain kinase 1 isoform 1. (640 aa) |
| | DISC1 | Disrupted in schizophrenia 1 protein isoform L. (851 aa) |
| | BCL11A | BAF chromatin remodeling complex subunit BCL11A. (835 aa) |
| | SPINT1 | Serine peptidase inhibitor, Kunitz type 1. (531 aa) |
| | ENSCJAP00000067889 | Hist_deacetyl domain-containing protein. (209 aa) |
| | XRCC5 | X-ray repair cross complementing 5. (800 aa) |
| | TSPO | Translocator protein. (203 aa) |
| | CX3CL1 | C-X3-C motif chemokine ligand 1. (429 aa) |
| | LPAR3 | Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (358 aa) |
| | TRIM32 | E3 ubiquitin-protein ligase TRIM32. (653 aa) |
| | DAG1 | Dystroglycan preproprotein. (895 aa) |
| | PLXNB3 | Plexin B3. (2035 aa) |
| | RAB21 | Ras-related protein Rab-21. (225 aa) |
| | ENSCJAP00000070626 | Uncharacterized protein. (225 aa) |
| | ASPA | Aspartoacylase. (313 aa) |
| | ENSCJAP00000071149 | Uncharacterized protein. (954 aa) |
| | NEURL1 | Neuralized E3 ubiquitin protein ligase 1. (657 aa) |
| | NTRK1 | Tyrosine-protein kinase receptor. (795 aa) |
| | SS18L1 | SS18L1 subunit of BAF chromatin remodeling complex. (416 aa) |
| | EPHB3 | EPH receptor B3. (1013 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | SHANK3 | SH3 and multiple ankyrin repeat domains 3. (1897 aa) |
| | CLSTN2 | Uncharacterized protein. (564 aa) |
| | ENSCJAP00000072238 | Homeobox domain-containing protein. (270 aa) |
| | SYNDIG1 | Synapse differentiation inducing 1. (291 aa) |
| | PLXNA1 | Plexin A1. (2224 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (1386 aa) |
| | VSTM5 | V-set and transmembrane domain containing 5. (200 aa) |
| | BMP2 | Bone morphogenetic protein 2. (401 aa) |
| | SOX10 | Transcription factor SOX-10. (467 aa) |
| | BDNF | Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (330 aa) |
| | GPER1 | G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | AMIGO3 | Amphoterin-induced protein 3. (504 aa) |
| | EGR2 | Early growth response 2. (486 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa) |
| | LRRTM1 | Leucine-rich repeat transmembrane neuronal protein 1. (522 aa) |
| | ZNF488 | Zinc finger protein 488. (233 aa) |
| | SLC7A5 | Solute carrier family 7 member 5. (328 aa) |
| | CHODL | Chondrolectin. (281 aa) |
| | ACY3 | Aminoacylase 3. (202 aa) |
| | FLRT3 | Leucine-rich repeat transmembrane protein FLRT3. (649 aa) |
| | ASIC2 | Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (618 aa) |
| | ENSCJAP00000077270 | Homeobox domain-containing protein. (263 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1296 aa) |
| | ENSCJAP00000077645 | MOEP19 domain-containing protein. (161 aa) |
| | ENSCJAP00000078142 | Uncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (397 aa) |
| | LRRN3 | Leucine-rich repeat neuronal protein 3. (708 aa) |
| | ENSCJAP00000078222 | Uncharacterized protein. (334 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (540 aa) |
