(29 nodes) Camera-type eye photoreceptor cell differentiation network (Callithrix jacchus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STAT3	Signal transducer and activator of transcription. (771 aa)
	CABP4	Calcium-binding protein 4. (272 aa)
	RORB	RAR related orphan receptor B. (470 aa)
	RPGRIP1L	RPGRIP1 like. (1268 aa)
	SOX8	SRY-box transcription factor 8. (538 aa)
	GNAT2	G protein subunit alpha transducin 2. (354 aa)
	THRB	Uncharacterized protein. (476 aa)
	CRB2	Crumbs cell polarity complex component 2. (1291 aa)
	TOPORS	E3 ubiquitin-protein ligase Topors isoform 1. (1045 aa)
	RPGRIP1	RPGR interacting protein 1. (1284 aa)
	USH1C	USH1 protein network component harmonin. (899 aa)
	BHLHE23	Basic helix-loop-helix family member e23. (242 aa)
	NOTCH1	Notch receptor 1. (2551 aa)
	NTRK2	Tyrosine-protein kinase receptor. (838 aa)
	PDE6C	Phosphodiesterase. (858 aa)
	RP1	RP1 axonemal microtubule associated. (2151 aa)
	TTC8	Tetratricopeptide repeat domain 8. (515 aa)
	BBS4	Bardet-Biedl syndrome 4. (518 aa)
	SDK2	Sidekick cell adhesion molecule 2. (2172 aa)
	NRL	Neural retina leucine zipper. (237 aa)
	IHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
	HCN1	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (886 aa)
	NAGLU	N-acetyl-alpha-glucosaminidase. (670 aa)
	ROM1	Retinal outer segment membrane protein 1. (351 aa)
	DSCAM	DS cell adhesion molecule. (2010 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	ENSCJAP00000074519	Uncharacterized protein. (681 aa)
	PROM1	Prominin 1. (865 aa)
	THY1	Thy-1 cell surface antigen. (165 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS4	RPGRIP1L	ENSCJAP00000033697	ENSCJAP00000002657	Bardet-Biedl syndrome 4.	RPGRIP1 like.	0.484
BBS4	TTC8	ENSCJAP00000033697	ENSCJAP00000032447	Bardet-Biedl syndrome 4.	Tetratricopeptide repeat domain 8.	0.989
CABP4	ROM1	ENSCJAP00000001599	ENSCJAP00000061704	Calcium-binding protein 4.	Retinal outer segment membrane protein 1.	0.485
CABP4	RPGRIP1	ENSCJAP00000001599	ENSCJAP00000017116	Calcium-binding protein 4.	RPGR interacting protein 1.	0.586
GNAT2	PDE6C	ENSCJAP00000005599	ENSCJAP00000028670	G protein subunit alpha transducin 2.	Phosphodiesterase.	0.951
GNAT2	ROM1	ENSCJAP00000005599	ENSCJAP00000061704	G protein subunit alpha transducin 2.	Retinal outer segment membrane protein 1.	0.564
GNAT2	RPGRIP1	ENSCJAP00000005599	ENSCJAP00000017116	G protein subunit alpha transducin 2.	RPGR interacting protein 1.	0.404
IHH	SOX9	ENSCJAP00000054739	ENSCJAP00000067837	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.585
NOTCH1	PROM1	ENSCJAP00000020179	ENSCJAP00000076400	Notch receptor 1.	Prominin 1.	0.473
NOTCH1	SOX9	ENSCJAP00000020179	ENSCJAP00000067837	Notch receptor 1.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.429
NOTCH1	STAT3	ENSCJAP00000020179	ENSCJAP00000000719	Notch receptor 1.	Signal transducer and activator of transcription.	0.616
PDE6C	GNAT2	ENSCJAP00000028670	ENSCJAP00000005599	Phosphodiesterase.	G protein subunit alpha transducin 2.	0.951
PDE6C	PROM1	ENSCJAP00000028670	ENSCJAP00000076400	Phosphodiesterase.	Prominin 1.	0.407
PDE6C	ROM1	ENSCJAP00000028670	ENSCJAP00000061704	Phosphodiesterase.	Retinal outer segment membrane protein 1.	0.639
PDE6C	RPGRIP1	ENSCJAP00000028670	ENSCJAP00000017116	Phosphodiesterase.	RPGR interacting protein 1.	0.425
PROM1	NOTCH1	ENSCJAP00000076400	ENSCJAP00000020179	Prominin 1.	Notch receptor 1.	0.473
PROM1	PDE6C	ENSCJAP00000076400	ENSCJAP00000028670	Prominin 1.	Phosphodiesterase.	0.407
PROM1	RPGRIP1	ENSCJAP00000076400	ENSCJAP00000017116	Prominin 1.	RPGR interacting protein 1.	0.501
PROM1	THY1	ENSCJAP00000076400	ENSCJAP00000076859	Prominin 1.	Thy-1 cell surface antigen.	0.402
ROM1	CABP4	ENSCJAP00000061704	ENSCJAP00000001599	Retinal outer segment membrane protein 1.	Calcium-binding protein 4.	0.485