STRINGSTRING
TBX5 TBX5 TBX2 TBX2 DNAH11 DNAH11 TGFBR3 TGFBR3 FGFRL1 FGFRL1 NSD2 NSD2 SEMA3C SEMA3C TGFBR2 TGFBR2 BMPR2 BMPR2 LRP2 LRP2 ZFPM2 ZFPM2 WNT5A WNT5A CHD7 CHD7 TBX3 TBX3 HAND1 HAND1 SMO SMO ISL1 ISL1 NOTCH1 NOTCH1 TGFBR1 TGFBR1 TBX20 TBX20 CCN1 CCN1 ZFPM1 ZFPM1 SLIT2 SLIT2 TGFB2 TGFB2 NRP1 NRP1 TBX1 TBX1 WNT11 WNT11 ACVR1 ACVR1 FGF8 FGF8 EGLN1 EGLN1 ENG ENG NOS3 NOS3 GATA6 GATA6 JAG1 JAG1 NRP2 NRP2 SAV1 SAV1 PROX1 PROX1 RBM15 RBM15 BMPR1A BMPR1A GATA4 GATA4 ROBO1 ROBO1 SLIT3 SLIT3 NOG NOG ROBO2 ROBO2 SMAD6 SMAD6 SMAD4 SMAD4 CITED2 CITED2 DHRS3 DHRS3 HEY1 HEY1 MKS1 MKS1 NOTCH2 NOTCH2 PARVA PARVA SMAD7 SMAD7 FGFR2 FGFR2 SOX11 SOX11 FZD2 FZD2 SOX4 SOX4 HEY2 HEY2 ENSCJAP00000069517 ENSCJAP00000069517 BMP4 BMP4 BMP7 BMP7 ENSCJAP00000071558 ENSCJAP00000071558 BMP5 BMP5 HEYL HEYL NKX2-5 NKX2-5 ENSCJAP00000078049 ENSCJAP00000078049
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX5T-box transcription factor TBX5 isoform 1. (518 aa)
TBX2T-box transcription factor 2. (713 aa)
DNAH11Dynein axonemal heavy chain 11. (4517 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform a. (851 aa)
FGFRL1Fibroblast growth factor receptor like 1. (503 aa)
NSD2Histone-lysine N-methyltransferase NSD2 isoform 1. (1365 aa)
SEMA3CSemaphorin-3C; Belongs to the semaphorin family. (751 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
LRP2LDL receptor related protein 2. (4656 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2994 aa)
TBX3T-box transcription factor TBX3 isoform 2. (743 aa)
HAND1Heart and neural crest derivatives expressed 1. (224 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
NOTCH1Notch receptor 1. (2551 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
TBX20T-box transcription factor 20. (447 aa)
CCN1Cellular communication network factor 1. (381 aa)
ZFPM1Zinc finger protein, FOG family member 1. (992 aa)
SLIT2Slit guidance ligand 2. (1527 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (927 aa)
TBX1T-box transcription factor 1. (506 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (476 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
EGLN1Uncharacterized protein. (426 aa)
ENGEndoglin. (655 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
GATA6GATA binding protein 6. (592 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
PROX1Prospero homeobox protein 1. (737 aa)
RBM15RNA binding motif protein 15. (970 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GATA4GATA binding protein 4. (442 aa)
ROBO1Roundabout guidance receptor 1. (1654 aa)
SLIT3Slit homolog 3 protein isoform 2. (1523 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ROBO2Roundabout guidance receptor 2. (1439 aa)
SMAD6Mothers against decapentaplegic homolog. (498 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CITED2Uncharacterized protein. (273 aa)
DHRS3Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform b. (308 aa)
MKS1Meckel syndrome type 1 protein isoform 1. (559 aa)
NOTCH2Notch receptor 2. (2470 aa)
PARVAParvin alpha. (492 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
SOX11Transcription factor SOX. (448 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
SOX4Transcription factor SOX. (472 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (338 aa)
ENSCJAP00000069517Uncharacterized protein. (251 aa)
BMP4Bone morphogenetic protein 4 preproprotein. (408 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
ENSCJAP00000071558TGF_BETA_2 domain-containing protein. (151 aa)
BMP5Bone morphogenetic protein 5. (472 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
NKX2-5NK2 homeobox 5. (324 aa)
ENSCJAP00000078049Uncharacterized protein. (161 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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