(30 nodes) Heart growth network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DCUN1D2	Uncharacterized protein. (1868 aa)
	MAP2K4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa)
	ADRA1A	Adrenoceptor alpha 1A. (466 aa)
	MESP1	Mesoderm posterior bHLH transcription factor 1. (279 aa)
	DIPK2A	Divergent protein kinase domain 2A. (481 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (338 aa)
	ENSCJAP00000071558	TGF_BETA_2 domain-containing protein. (151 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (332 aa)
	ENSCJAP00000075743	Uncharacterized protein. (125 aa)
	NKX2-5	NK2 homeobox 5. (324 aa)
	TGFBR3	Transforming growth factor beta receptor type 3 isoform a. (851 aa)
	SORBS2	Sorbin and SH3 domain containing 2. (1594 aa)
	S1PR1	Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	WNT2	Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
	JARID2	Jumonji and AT-rich interaction domain containing 2. (1240 aa)
	SMAD1	Mothers against decapentaplegic homolog. (469 aa)
	F6PY39_CALJA	PDZ and LIM domain 5. (681 aa)
	TBX5	T-box transcription factor TBX5 isoform 1. (518 aa)
	NOTCH1	Notch receptor 1. (2551 aa)
	NDRG4	NDRG family member 4. (391 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	AKAP13	A-kinase anchoring protein 13. (2816 aa)
	ARID2	AT-rich interaction domain 2. (1836 aa)
	TENM4	Teneurin transmembrane protein 4. (2769 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	GATA6	GATA binding protein 6. (592 aa)
	SAV1	Salvador family WW domain containing protein 1. (384 aa)
	GATA4	GATA binding protein 4. (442 aa)
	FOXC2	Forkhead box C2. (501 aa)
	ENSCJAP00000077596	Uncharacterized protein. (100 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCJAP00000071558	TGFBR3	ENSCJAP00000071558	ENSCJAP00000003213	TGF_BETA_2 domain-containing protein.	Transforming growth factor beta receptor type 3 isoform a.	0.562
ENSCJAP00000075743	SORBS2	ENSCJAP00000075743	ENSCJAP00000005634	Uncharacterized protein.	Sorbin and SH3 domain containing 2.	0.464
F6PY39_CALJA	SORBS2	ENSCJAP00000012805	ENSCJAP00000005634	PDZ and LIM domain 5.	Sorbin and SH3 domain containing 2.	0.464
GATA4	HEY2	ENSCJAP00000052123	ENSCJAP00000067830	GATA binding protein 4.	Hes related family bHLH transcription factor with YRPW motif 2.	0.468
GATA4	MESP1	ENSCJAP00000052123	ENSCJAP00000063057	GATA binding protein 4.	Mesoderm posterior bHLH transcription factor 1.	0.488
GATA4	NKX2-5	ENSCJAP00000052123	ENSCJAP00000075732	GATA binding protein 4.	NK2 homeobox 5.	0.956
GATA4	TBX5	ENSCJAP00000052123	ENSCJAP00000017954	GATA binding protein 4.	T-box transcription factor TBX5 isoform 1.	0.935
GATA6	NKX2-5	ENSCJAP00000038164	ENSCJAP00000075732	GATA binding protein 6.	NK2 homeobox 5.	0.815
GATA6	TBX5	ENSCJAP00000038164	ENSCJAP00000017954	GATA binding protein 6.	T-box transcription factor TBX5 isoform 1.	0.514
HEY2	GATA4	ENSCJAP00000067830	ENSCJAP00000052123	Hes related family bHLH transcription factor with YRPW motif 2.	GATA binding protein 4.	0.468
HEY2	NOTCH1	ENSCJAP00000067830	ENSCJAP00000020179	Hes related family bHLH transcription factor with YRPW motif 2.	Notch receptor 1.	0.667
HEY2	TBX5	ENSCJAP00000067830	ENSCJAP00000017954	Hes related family bHLH transcription factor with YRPW motif 2.	T-box transcription factor TBX5 isoform 1.	0.410
JARID2	TBX5	ENSCJAP00000010520	ENSCJAP00000017954	Jumonji and AT-rich interaction domain containing 2.	T-box transcription factor TBX5 isoform 1.	0.421
MESP1	GATA4	ENSCJAP00000063057	ENSCJAP00000052123	Mesoderm posterior bHLH transcription factor 1.	GATA binding protein 4.	0.488
MESP1	NKX2-5	ENSCJAP00000063057	ENSCJAP00000075732	Mesoderm posterior bHLH transcription factor 1.	NK2 homeobox 5.	0.414
NKX2-5	GATA4	ENSCJAP00000075732	ENSCJAP00000052123	NK2 homeobox 5.	GATA binding protein 4.	0.956
NKX2-5	GATA6	ENSCJAP00000075732	ENSCJAP00000038164	NK2 homeobox 5.	GATA binding protein 6.	0.815
NKX2-5	MESP1	ENSCJAP00000075732	ENSCJAP00000063057	NK2 homeobox 5.	Mesoderm posterior bHLH transcription factor 1.	0.414
NKX2-5	NOTCH1	ENSCJAP00000075732	ENSCJAP00000020179	NK2 homeobox 5.	Notch receptor 1.	0.402
NKX2-5	TBX5	ENSCJAP00000075732	ENSCJAP00000017954	NK2 homeobox 5.	T-box transcription factor TBX5 isoform 1.	0.977