STRINGSTRING
RARG RARG WNT7B WNT7B ENSCJAP00000071886 ENSCJAP00000071886 BMP4 BMP4 SOX9 SOX9 FOXF1 FOXF1 LEF1 LEF1 MAPK3 MAPK3 EDA EDA MAPK1 MAPK1 SHH SHH CTNNB1 CTNNB1 HYDIN HYDIN RARA RARA HOXA5 HOXA5 RSPO2 RSPO2 SRF SRF TGFBR2 TGFBR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RARGRetinoic acid receptor gamma isoform 1. (454 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ENSCJAP00000071886Uncharacterized protein. (155 aa)
BMP4Bone morphogenetic protein 4 preproprotein. (408 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
FOXF1Forkhead box F1. (430 aa)
LEF1Lymphoid enhancer binding factor 1. (419 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa)
EDATNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (389 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
CTNNB1Catenin beta 1. (774 aa)
HYDINHYDIN axonemal central pair apparatus protein. (5118 aa)
RARAUncharacterized protein. (468 aa)
HOXA5Homeobox A5 (Predicted). (270 aa)
RSPO2R-spondin-2. (243 aa)
SRFSerum response factor. (509 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.