STRINGSTRING
KDM5B KDM5B ELF3 ELF3 TGFBR2 TGFBR2 MST1 MST1 AR AR CSF1 CSF1 CSMD2 CSMD2 BSX BSX GLI3 GLI3 WNT5A WNT5A EPHA2 EPHA2 MED1 MED1 TBX3 TBX3 AREG AREG VDR VDR NFKB1 NFKB1 LRP5 LRP5 BTRC BTRC PML PML ESR1 ESR1 TGFB1 TGFB1 CSF1R CSF1R DDR1 DDR1 FGF10 FGF10 PTCH1 PTCH1 SOSTDC1 SOSTDC1 NTN1 NTN1 NRG3 NRG3 FGFR2 FGFR2 WNT4 WNT4 IGFBP5 IGFBP5 BMP4 BMP4 STAT6 STAT6 TBX2 TBX2 SRC SRC SCRIB SCRIB CSMD1 CSMD1 LRRC1 LRRC1 PGR PGR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KDM5BLysine demethylase 5B. (1544 aa)
ELF3E74 like ETS transcription factor 3. (371 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
ARAndrogen receptor. (887 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (549 aa)
CSMD2CUB and Sushi multiple domains 2. (3702 aa)
BSXBrain specific homeobox. (232 aa)
GLI3GLI family zinc finger 3. (1578 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
EPHA2EPH receptor A2. (976 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
TBX3T-box transcription factor TBX3 isoform 2. (743 aa)
AREGAmphiregulin. (275 aa)
VDRVitamin D receptor. (427 aa)
NFKB1Nuclear factor kappa B subunit 1. (998 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
PMLPromyelocytic leukemia. (881 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (913 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
PTCH1Protein patched homolog 1 isoform L. (1449 aa)
SOSTDC1CTCK domain-containing protein. (230 aa)
NTN1Netrin-1. (604 aa)
NRG3Neuregulin 3. (720 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
IGFBP5Insulin like growth factor binding protein 5. (275 aa)
BMP4Bone morphogenetic protein 4 preproprotein. (408 aa)
STAT6Signal transducer and activator of transcription. (865 aa)
TBX2T-box transcription factor 2. (713 aa)
SRCTyrosine-protein kinase. (553 aa)
SCRIBUncharacterized protein. (1686 aa)
CSMD1CUB and Sushi multiple domains 1. (3562 aa)
LRRC1Leucine-rich repeat-containing protein 1. (524 aa)
PGRProgesterone receptor. (935 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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