(45 nodes) Regulation of miRNA-mediated gene silencing network (Callithrix jacchus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

Predicted Interactions

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Your Input:
	NCOR1	Nuclear receptor corepressor 1. (2436 aa)
	WTIP	Wilms tumor protein 1-interacting protein. (428 aa)
	LIN28A	Lin-28 homolog A. (209 aa)
	AJUBA	LIM domain-containing protein ajuba isoform 1. (538 aa)
	PUM2	Pumilio homolog 2. (1066 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
	RIPK1	Receptor-interacting serine/threonine-protein kinase 1. (670 aa)
	PUM1	Pumilio RNA binding family member 1. (1226 aa)
	DHX9	DExH-box helicase 9. (1286 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
	STAT3	Signal transducer and activator of transcription. (771 aa)
	DDX5	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (614 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	TIAL1	Uncharacterized protein. (441 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	BCDIN3D	BCDIN3 domain containing RNA methyltransferase. (293 aa)
	F7I9C7_CALJA	CCHC-type domain-containing protein. (209 aa)
	F7F298_CALJA	CSP domain-containing protein. (208 aa)
	ELAVL1	ELAV-like protein; Belongs to the RRM elav family. (326 aa)
	IL6	Interleukin 6. (212 aa)
	NCOR2	Nuclear receptor corepressor 2. (2498 aa)
	TNF	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (232 aa)
	ENSCJAP00000054025	CCHC-type domain-containing protein. (211 aa)
	LIN28B	Lin-28 homolog B. (260 aa)
	ENSCJAP00000056213	Uncharacterized protein. (92 aa)
	FMR1	Uncharacterized protein. (650 aa)
	MYCN	MYCN proto-oncogene, bHLH transcription factor. (464 aa)
	TRUB1	TruB pseudouridine synthase family member 1. (351 aa)
	ZC3H10	Zinc finger CCCH domain-containing protein 10. (434 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (521 aa)
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (287 aa)
	ENSCJAP00000068201	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (964 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (598 aa)
	ENSCJAP00000070021	Uncharacterized protein. (129 aa)
	BMP4	Bone morphogenetic protein 4 preproprotein. (408 aa)
	EGFR	Receptor protein-tyrosine kinase. (1210 aa)
	ENSCJAP00000077524	CSP domain-containing protein. (234 aa)
	LOC100388273	CCHC-type domain-containing protein. (207 aa)
	MAEL	Maelstrom spermatogenic transposon silencer. (403 aa)
	DND1	DND microRNA-mediated repression inhibitor 1. (353 aa)
	EIF4G1	Eukaryotic translation initiation factor 4 gamma 1. (1599 aa)
	ZFP36	ZFP36 ring finger protein. (332 aa)
	HNF1A	HNF1 homeobox A. (638 aa)
	FXR1	FMR1 autosomal homolog 1. (648 aa)
	TRIM71	Tripartite motif containing 71. (868 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJUBA	ENSCJAP00000070021	ENSCJAP00000015429	ENSCJAP00000070021	LIM domain-containing protein ajuba isoform 1.	Uncharacterized protein.	0.947
AJUBA	NCOR1	ENSCJAP00000015429	ENSCJAP00000022329	LIM domain-containing protein ajuba isoform 1.	Nuclear receptor corepressor 1.	0.553
AJUBA	WTIP	ENSCJAP00000015429	ENSCJAP00000019893	LIM domain-containing protein ajuba isoform 1.	Wilms tumor protein 1-interacting protein.	0.946
BCDIN3D	ZC3H10	ENSCJAP00000039160	ENSCJAP00000066356	BCDIN3 domain containing RNA methyltransferase.	Zinc finger CCCH domain-containing protein 10.	0.586
BMP4	IL6	ENSCJAP00000070142	ENSCJAP00000047799	Bone morphogenetic protein 4 preproprotein.	Interleukin 6.	0.460
BMP4	STAT3	ENSCJAP00000070142	ENSCJAP00000000719	Bone morphogenetic protein 4 preproprotein.	Signal transducer and activator of transcription.	0.409
DDX5	DHX9	ENSCJAP00000035916	ENSCJAP00000009059	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	DExH-box helicase 9.	0.935
DDX5	EIF4G1	ENSCJAP00000035916	ENSCJAP00000027835	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 4 gamma 1.	0.426
DDX5	ESR1	ENSCJAP00000035916	ENSCJAP00000036232	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.874
DDX5	FXR1	ENSCJAP00000035916	ENSCJAP00000023572	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	FMR1 autosomal homolog 1.	0.416
DDX5	NCOR1	ENSCJAP00000035916	ENSCJAP00000022329	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	Nuclear receptor corepressor 1.	0.431
DDX5	TRUB1	ENSCJAP00000035916	ENSCJAP00000064263	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	TruB pseudouridine synthase family member 1.	0.541
DHX9	DDX5	ENSCJAP00000009059	ENSCJAP00000035916	DExH-box helicase 9.	Putative ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	0.935
DHX9	EGFR	ENSCJAP00000009059	ENSCJAP00000074658	DExH-box helicase 9.	Receptor protein-tyrosine kinase.	0.413
DHX9	ELAVL1	ENSCJAP00000009059	ENSCJAP00000044012	DExH-box helicase 9.	ELAV-like protein; Belongs to the RRM elav family.	0.626
DHX9	ZFP36	ENSCJAP00000009059	ENSCJAP00000026025	DExH-box helicase 9.	ZFP36 ring finger protein.	0.465
DND1	TIAL1	ENSCJAP00000030092	ENSCJAP00000036589	DND microRNA-mediated repression inhibitor 1.	Uncharacterized protein.	0.491
EGFR	DHX9	ENSCJAP00000074658	ENSCJAP00000009059	Receptor protein-tyrosine kinase.	DExH-box helicase 9.	0.413
EGFR	ESR1	ENSCJAP00000074658	ENSCJAP00000036232	Receptor protein-tyrosine kinase.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.905
EGFR	FMR1	ENSCJAP00000074658	ENSCJAP00000056898	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.400