STRINGSTRING
SRSF5 SRSF5 HNF1B HNF1B HNRNPD HNRNPD CPT1A CPT1A MAN2A1 MAN2A1 MKS1 MKS1 NOTCH2 NOTCH2 LSR LSR GFER GFER ONECUT2 ONECUT2 ATP7A ATP7A JUN JUN CLDN1 CLDN1 WNT4 WNT4 SOX9 SOX9 CCDC40 CCDC40 ENSCJAP00000069517 ENSCJAP00000069517 ENSCJAP00000070626 ENSCJAP00000070626 ENSCJAP00000071395 ENSCJAP00000071395 ENSCJAP00000072111 ENSCJAP00000072111 BAAT BAAT DNAAF1 DNAAF1 FGL1 FGL1 PDX1 PDX1 RELA RELA SLC7A5 SLC7A5 MPST MPST JUND JUND PCSK9 PCSK9 SOX17 SOX17 ARID5B ARID5B FRZB FRZB NODAL NODAL PTCD2 PTCD2 CPB2 CPB2 PHF2 PHF2 ADA ADA HNF4A HNF4A NIPBL NIPBL TGFA TGFA FPGS FPGS HMGCS2 HMGCS2 RHBDD3 RHBDD3 XBP1 XBP1 TGFB1 TGFB1 GATA6 GATA6 ASS1 ASS1 OTC OTC WNT1 WNT1 PTPN3 PTPN3 IL6 IL6 CEBPG CEBPG PROX1 PROX1 PCK2 PCK2 CPS1 CPS1 CDK5RAP3 CDK5RAP3 CCND1 CCND1 IHH IHH E2F7 E2F7 ARF6 ARF6 CITED2 CITED2 CEBPB CEBPB PTCH1 PTCH1 ALDH1A2 ALDH1A2 CADM1 CADM1 NKX2-8 NKX2-8 TYMS TYMS RPGRIP1L RPGRIP1L ITGA2 ITGA2 TGFBR3 TGFBR3 SMAD3 SMAD3 ZMPSTE24 ZMPSTE24 HGF HGF C6orf58 C6orf58 ACO2 ACO2 PRKCSH PRKCSH JARID2 JARID2 SEC63 SEC63 PKD2 PKD2 E2F8 E2F8 GLI1 GLI1 SP3 SP3 ATF2 ATF2 MED1 MED1 CIT CIT TBX3 TBX3 RPS6KA1 RPS6KA1 EZH2 EZH2 SMARCB1 SMARCB1 NOTCH1 NOTCH1 AURKA AURKA CSNK2A2 CSNK2A2 IGF2R IGF2R CUL3 CUL3 ELK1 ELK1 CCDC39 CCDC39 PIK3CA PIK3CA RARA RARA HNF1A HNF1A COBL COBL ZIC3 ZIC3 TAF10 TAF10 NF1 NF1 UPF2 UPF2 RB1CC1 RB1CC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
HNF1BHNF1 homeobox B. (567 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D0 isoform a. (355 aa)
CPT1ACarnitine O-palmitoyltransferase 1, liver isoform isoform 1; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
MAN2A1Alpha-mannosidase. (1144 aa)
MKS1Meckel syndrome type 1 protein isoform 1. (559 aa)
NOTCH2Notch receptor 2. (2470 aa)
LSRLipolysis stimulated lipoprotein receptor. (640 aa)
GFERSulfhydryl oxidase. (206 aa)
ONECUT2One cut domain family member. (505 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
CCDC40Coiled-coil domain containing 40. (1207 aa)
ENSCJAP00000069517Uncharacterized protein. (251 aa)
ENSCJAP00000070626Uncharacterized protein. (225 aa)
ENSCJAP00000071395BZIP domain-containing protein. (345 aa)
ENSCJAP00000072111PRC2_HTH_1 domain-containing protein. (366 aa)
BAATBile acid-CoA:amino acid N-acyltransferase. (464 aa)
DNAAF1Dynein assembly factor 1, axonemal. (765 aa)
FGL1Fibrinogen like 1. (327 aa)
PDX1Homeobox domain-containing protein. (282 aa)
RELARELA proto-oncogene, NF-kB subunit. (571 aa)
SLC7A5Solute carrier family 7 member 5. (328 aa)
MPSTSulfurtransferase. (351 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (318 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9; Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway. May prevent the recycling of LDLR from endosomes to [...] (690 aa)
SOX17SRY-box transcription factor 17. (414 aa)
ARID5BAT-rich interaction domain 5B. (1188 aa)
FRZBFrizzled related protein. (412 aa)
NODALNodal growth differentiation factor. (346 aa)
PTCD2Pentatricopeptide repeat-containing protein 2, mitochondrial. (388 aa)
CPB2Carboxypeptidase B2. (423 aa)
PHF2Lysine-specific demethylase PHF2. (1102 aa)
ADAAdenosine deaminase. (363 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
NIPBLNipped-B protein. (2804 aa)
TGFATransforming growth factor alpha. (165 aa)
FPGSFolylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (586 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
RHBDD3Rhomboid domain-containing protein 3. (386 aa)
XBP1BZIP domain-containing protein. (371 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GATA6GATA binding protein 6. (592 aa)
ASS1Argininosuccinate synthase 1. (412 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (354 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (913 aa)
IL6Interleukin 6. (212 aa)
CEBPGCCAAT enhancer binding protein gamma. (150 aa)
PROX1Prospero homeobox protein 1. (737 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform 1. (640 aa)
CPS1Carbamoyl-phosphate synthase 1. (1507 aa)
CDK5RAP3CDK5 regulatory subunit-associated protein 3. (505 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (531 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
E2F7E2F transcription factor 7. (910 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
CITED2Uncharacterized protein. (273 aa)
CEBPBCCAAT/enhancer-binding protein. (344 aa)
PTCH1Protein patched homolog 1 isoform L. (1449 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
CADM1Cell adhesion molecule 1. (472 aa)
NKX2-8NK2 homeobox 8. (241 aa)
TYMSThymidylate synthetase. (313 aa)
RPGRIP1LRPGRIP1 like. (1268 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1181 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform a. (851 aa)
SMAD3Mothers against decapentaplegic homolog. (437 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
HGFHepatocyte growth factor; Belongs to the peptidase S1 family. (813 aa)
C6orf58Chromosome 6 open reading frame 58. (330 aa)
ACO2Aconitase 2. (805 aa)
PRKCSHGlucosidase 2 subunit beta isoform 1. (536 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1240 aa)
SEC63Translocation protein SEC63 homolog. (760 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (973 aa)
E2F8E2F transcription factor 8. (867 aa)
GLI1GLI family zinc finger 1. (1106 aa)
SP3Sp3 transcription factor. (782 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2058 aa)
TBX3T-box transcription factor TBX3 isoform 2. (743 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (409 aa)
NOTCH1Notch receptor 1. (2551 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (401 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
IGF2RInsulin like growth factor 2 receptor. (2324 aa)
CUL3Cullin-3 isoform 1; Belongs to the cullin family. (768 aa)
ELK1ETS transcription factor ELK1. (479 aa)
CCDC39Coiled-coil domain containing 39. (970 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RARAUncharacterized protein. (468 aa)
HNF1AHNF1 homeobox A. (638 aa)
COBLCordon-bleu WH2 repeat protein. (1274 aa)
ZIC3Zinc finger protein ZIC 3. (467 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (217 aa)
NF1Neurofibromin 1. (2839 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1271 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform 1. (1594 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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