STRINGSTRING
INTS8 INTS8 SMAD3 SMAD3 SMAD2 SMAD2 SMAD1 SMAD1 TGFBR1 TGFBR1 AXIN1 AXIN1 AXIN2 AXIN2 CTNNB1 CTNNB1 SMURF1 SMURF1 SMAD6 SMAD6 SMAD4 SMAD4 SMAD9 SMAD9 SMAD7 SMAD7 TGFB1I1 TGFB1I1 ENSCJAP00000069714 ENSCJAP00000069714
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INTS8Integrator complex subunit 8. (995 aa)
SMAD3Mothers against decapentaplegic homolog. (437 aa)
SMAD2Mothers against decapentaplegic homolog. (494 aa)
SMAD1Mothers against decapentaplegic homolog. (469 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
AXIN1Axin-1 isoform a. (867 aa)
AXIN2Axin-2. (842 aa)
CTNNB1Catenin beta 1. (774 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
SMAD6Mothers against decapentaplegic homolog. (498 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (469 aa)
ENSCJAP00000069714MH2 domain-containing protein. (253 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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