STRINGSTRING
FGF10 FGF10 ELL3 ELL3 EIF2AK2 EIF2AK2 RARB RARB TGFBR2 TGFBR2 OVOL2 OVOL2 PIM1 PIM1 KDM1A KDM1A KAT7 KAT7 FERMT2 FERMT2 GLI3 GLI3 WNT5A WNT5A HOXA3 HOXA3 TBX3 TBX3 PRRX1 PRRX1 KDF1 KDF1 DGCR8 DGCR8 NOTCH1 NOTCH1 NFIB NFIB SNAI2 SNAI2 NF1 NF1 F6X2E4_CALJA F6X2E4_CALJA FGF4 FGF4 IRF6 IRF6 SIRT6 SIRT6 WNT11 WNT11 HNRNPU HNRNPU FGF8 FGF8 CTNNB1 CTNNB1 KDR KDR KITLG KITLG TIAL1 TIAL1 ACE ACE NF2 NF2 TGFB1 TGFB1 SHH SHH F7I6Z0_CALJA F7I6Z0_CALJA WNT10B WNT10B WNT1 WNT1 FERMT1 FERMT1 SOX18 SOX18 ATXN1L ATXN1L N4BP2L2 N4BP2L2 PTPRC PTPRC NR2E1 NR2E1 PDCD2 PDCD2 RARG RARG TP63 TP63 VEGFC VEGFC IRS2 IRS2 ENSCJAP00000056213 ENSCJAP00000056213 CD109 CD109 ENSCJAP00000056577 ENSCJAP00000056577 PTCH1 PTCH1 ID4 ID4 SHOX2 SHOX2 ENSCJAP00000064549 ENSCJAP00000064549 ENSCJAP00000064965 ENSCJAP00000064965 SFN SFN SOX11 SOX11 SOX9 SOX9 CDKN2C CDKN2C ENSCJAP00000067987 ENSCJAP00000067987 TERT TERT ENSCJAP00000068201 ENSCJAP00000068201 ENSCJAP00000068891 ENSCJAP00000068891 ENSCJAP00000069100 ENSCJAP00000069100 FBLN1 FBLN1 ENSCJAP00000070597 ENSCJAP00000070597 ENSCJAP00000071234 ENSCJAP00000071234 OSR2 OSR2 ZFP36L1 ZFP36L1 GJA1 GJA1 FGF9 FGF9 RUNX2 RUNX2 ENSCJAP00000076309 ENSCJAP00000076309 SOX17 SOX17 ENSCJAP00000076525 ENSCJAP00000076525 ENSCJAP00000077980 ENSCJAP00000077980 ENSCJAP00000078638 ENSCJAP00000078638 EPCAM EPCAM YAP1 YAP1 AGO3 AGO3 CCNE1 CCNE1 OVOL1 OVOL1 LTBP3 LTBP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
ELL3Elongation factor RNA polymerase II-like 3 (Predicted). (398 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2. (552 aa)
RARBRetinoic acid receptor beta isoform 1. (448 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
OVOL2Transcription factor Ovo-like 2. (275 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
FERMT2PH domain-containing protein. (687 aa)
GLI3GLI family zinc finger 3. (1578 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
HOXA3Homeobox A3 isoform a (Predicted). (443 aa)
TBX3T-box transcription factor TBX3 isoform 2. (743 aa)
PRRX1Paired related homeobox 1. (245 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
DGCR8Microprocessor complex subunit DGCR8 isoform 1. (773 aa)
NOTCH1Notch receptor 1. (2551 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
NF1Neurofibromin 1. (2839 aa)
F6X2E4_CALJAMYND-type domain-containing protein. (252 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
IRF6Interferon regulatory factor 6 isoform 1. (462 aa)
SIRT6NAD-dependent protein deacetylase sirtuin-6 isoform 1. (355 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (476 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform a. (825 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
CTNNB1Catenin beta 1. (774 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
TIAL1Uncharacterized protein. (441 aa)
ACEAngiotensin-converting enzyme. (1306 aa)
NF2Merlin isoform 1. (595 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
F7I6Z0_CALJAMYND-type domain-containing protein. (329 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FERMT1Fermitin family member 1. (717 aa)
SOX18SRY-box transcription factor 18. (377 aa)
ATXN1LAtaxin-1-like. (689 aa)
N4BP2L2NEDD4 binding protein 2 like 2. (749 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1252 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
PDCD2MYND-type domain-containing protein. (343 aa)
RARGRetinoic acid receptor gamma isoform 1. (454 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (402 aa)
IRS2Insulin receptor substrate 2. (1327 aa)
ENSCJAP00000056213Uncharacterized protein. (92 aa)
CD109CD109 antigen isoform 1. (1445 aa)
ENSCJAP00000056577Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (277 aa)
PTCH1Protein patched homolog 1 isoform L. (1449 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
SHOX2Short stature homeobox 2. (319 aa)
ENSCJAP00000064549Uncharacterized protein. (118 aa)
ENSCJAP00000064965Uncharacterized protein. (130 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
SOX11Transcription factor SOX. (448 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
ENSCJAP00000067987Uncharacterized protein. (74 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (287 aa)
ENSCJAP00000068201Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (964 aa)
ENSCJAP00000068891Uncharacterized protein. (94 aa)
ENSCJAP00000069100Uncharacterized protein. (104 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (759 aa)
ENSCJAP00000070597Uncharacterized protein. (87 aa)
ENSCJAP00000071234MYND-type domain-containing protein. (333 aa)
OSR2Protein odd-skipped-related 2 isoform b. (276 aa)
ZFP36L1Uncharacterized protein. (338 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (400 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (332 aa)
RUNX2RUNX family transcription factor 2. (645 aa)
ENSCJAP00000076309Angiotensin-converting enzyme. (703 aa)
SOX17SRY-box transcription factor 17. (414 aa)
ENSCJAP00000076525Uncharacterized protein. (94 aa)
ENSCJAP00000077980Uncharacterized protein. (446 aa)
ENSCJAP00000078638Uncharacterized protein. (134 aa)
EPCAMEpithelial cell adhesion molecule. (173 aa)
YAP1Yes associated protein 1. (507 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa)
OVOL1Ovo like transcriptional repressor 1. (267 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1300 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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