(15 nodes) Ureter development network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	RET	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
	SOX8	SRY-box transcription factor 8. (538 aa)
	OSR1	Odd-skipped related transcription factor 1. (266 aa)
	NFIA	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (554 aa)
	GATA3	GATA binding protein 3. (444 aa)
	LZTS2	Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
	ALDH1A2	Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
	EMX2	Homeobox protein EMX2 isoform 1. (252 aa)
	TBX18	T-box transcription factor 18. (607 aa)
	FOXF1	Forkhead box F1. (430 aa)
	PAX2	Paired box 2. (448 aa)
	SOX9	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
	BMP4	Bone morphogenetic protein 4 preproprotein. (408 aa)
	LHX1	LIM homeobox 1. (456 aa)
	SOX17	SRY-box transcription factor 17. (414 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	FOXF1	ENSCJAP00000070142	ENSCJAP00000060467	Bone morphogenetic protein 4 preproprotein.	Forkhead box F1.	0.606
BMP4	GATA3	ENSCJAP00000070142	ENSCJAP00000053176	Bone morphogenetic protein 4 preproprotein.	GATA binding protein 3.	0.432
BMP4	SOX17	ENSCJAP00000070142	ENSCJAP00000076388	Bone morphogenetic protein 4 preproprotein.	SRY-box transcription factor 17.	0.727
BMP4	SOX9	ENSCJAP00000070142	ENSCJAP00000067837	Bone morphogenetic protein 4 preproprotein.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.446
EMX2	SOX9	ENSCJAP00000058946	ENSCJAP00000067837	Homeobox protein EMX2 isoform 1.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.404
FOXF1	BMP4	ENSCJAP00000060467	ENSCJAP00000070142	Forkhead box F1.	Bone morphogenetic protein 4 preproprotein.	0.606
GATA3	BMP4	ENSCJAP00000053176	ENSCJAP00000070142	GATA binding protein 3.	Bone morphogenetic protein 4 preproprotein.	0.432
GATA3	LHX1	ENSCJAP00000053176	ENSCJAP00000071420	GATA binding protein 3.	LIM homeobox 1.	0.415
GATA3	SOX17	ENSCJAP00000053176	ENSCJAP00000076388	GATA binding protein 3.	SRY-box transcription factor 17.	0.578
LHX1	GATA3	ENSCJAP00000071420	ENSCJAP00000053176	LIM homeobox 1.	GATA binding protein 3.	0.415
LHX1	PAX2	ENSCJAP00000071420	ENSCJAP00000066740	LIM homeobox 1.	Paired box 2.	0.620
NFIA	SOX9	ENSCJAP00000029781	ENSCJAP00000067837	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.597
PAX2	LHX1	ENSCJAP00000066740	ENSCJAP00000071420	Paired box 2.	LIM homeobox 1.	0.620
PAX2	SOX9	ENSCJAP00000066740	ENSCJAP00000067837	Paired box 2.	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	0.488
SOX17	BMP4	ENSCJAP00000076388	ENSCJAP00000070142	SRY-box transcription factor 17.	Bone morphogenetic protein 4 preproprotein.	0.727
SOX17	GATA3	ENSCJAP00000076388	ENSCJAP00000053176	SRY-box transcription factor 17.	GATA binding protein 3.	0.578
SOX9	BMP4	ENSCJAP00000067837	ENSCJAP00000070142	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Bone morphogenetic protein 4 preproprotein.	0.446
SOX9	EMX2	ENSCJAP00000067837	ENSCJAP00000058946	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Homeobox protein EMX2 isoform 1.	0.404
SOX9	NFIA	ENSCJAP00000067837	ENSCJAP00000029781	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.	0.597
SOX9	PAX2	ENSCJAP00000067837	ENSCJAP00000066740	Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.	Paired box 2.	0.488