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| | CSNK1A1 | Casein kinase I isoform alpha isoform 1; Belongs to the protein kinase superfamily. (365 aa) |
| | FERMT1 | Fermitin family member 1. (717 aa) |
| | PTPRO | Protein tyrosine phosphatase receptor type O. (1216 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (462 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (837 aa) |
| | DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) |
| | LATS2 | Non-specific serine/threonine protein kinase. (1085 aa) |
| | UBAC2 | UBA domain containing 2. (392 aa) |
| | GSK3A | Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (538 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa) |
| | SCYL2 | SCY1-like protein 2. (933 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (388 aa) |
| | SFRP5 | Secreted frizzled related protein 5. (315 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa) |
| | TLE7 | WD_REPEATS_REGION domain-containing protein. (440 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | TMEM88 | Transmembrane protein 88. (158 aa) |
| | STK3 | Serine/threonine-protein kinase 3 isoform 1. (491 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | ZNRF3 | Zinc and ring finger 3. (933 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa) |
| | SFRP4 | Secreted frizzled related protein 4. (346 aa) |
| | STK4 | Serine/threonine-protein kinase 4. (487 aa) |
| | SOSTDC1 | CTCK domain-containing protein. (230 aa) |
| | TBX18 | T-box transcription factor 18. (607 aa) |
| | ENSCJAP00000059748 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (195 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2301 aa) |
| | MCC | Uncharacterized protein. (1010 aa) |
| | OTUD5 | OTU deubiquitinase 5. (571 aa) |
| | NPPA | Natriuretic peptide A. (153 aa) |
| | DRAXIN | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (348 aa) |
| | MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B. (211 aa) |
| | APOE | Apolipoprotein E. (320 aa) |
| | AMFR | Autocrine motility factor receptor. (765 aa) |
| | EMD | Emerin (Predicted). (258 aa) |
| | MDK | Midkine isoform a. (144 aa) |
| | AXIN1 | Axin-1 isoform a. (867 aa) |
| | F6TG91_CALJA | Uncharacterized protein. (159 aa) |
| | INVS | Inversin. (1079 aa) |
| | SFRP1 | Secreted frizzled-related protein 1. (314 aa) |
| | NOTCH1 | Notch receptor 1. (2551 aa) |
| | ISL1 | Insulin gene enhancer protein ISL-1. (349 aa) |
| | BICC1 | BicC family RNA binding protein 1. (974 aa) |
| | LATS1 | Serine/threonine-protein kinase LATS1 isoform 1. (1128 aa) |
| | CHD8 | Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2584 aa) |
| | TNN | Tenascin N. (1299 aa) |
| | CTNND1 | Catenin delta 1. (983 aa) |
| | DKK4 | Dickkopf WNT signaling pathway inhibitor 4. (224 aa) |
| | HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1605 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa) |
| | GLI3 | GLI family zinc finger 3. (1578 aa) |
| | DAB2 | Disabled homolog 2 isoform 1. (767 aa) |
| | GLI1 | GLI family zinc finger 1. (1106 aa) |
| | TLE3 | TLE family member 3, transcriptional corepressor. (829 aa) |
| | F6QBC1_CALJA | Uncharacterized protein. (113 aa) |
| | TMEM170B | Transmembrane protein 170B. (132 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (108 aa) |
| | FUZ | Fuzzy planar cell polarity protein. (418 aa) |
| | TLE4 | TLE family member 4, transcriptional corepressor. (771 aa) |
| | JADE1 | Protein Jade-1 long isoform. (843 aa) |
| | TMEM131L | Transmembrane 131 like. (1610 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (549 aa) |
| | CYLD | Ubiquitin carboxyl-terminal hydrolase CYLD isoform 1; Belongs to the peptidase C19 family. (956 aa) |
| | WWTR1 | WW domain-containing protein. (400 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | F7HDR0_CALJA | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (453 aa) |
| | DKKL1 | Dickkopf like acrosomal protein 1. (242 aa) |
| | NPHP4 | Nephrocystin 4. (1345 aa) |
| | SNAI2 | Snail family transcriptional repressor 2. (268 aa) |
| | IGFBP4 | Insulin-like growth factor-binding protein 4. (258 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (476 aa) |
| | G3BP1 | Ras GTPase-activating protein-binding protein 1. (466 aa) |
| | TLE5 | TLE family member 5, transcriptional modulator. (191 aa) |
| | APC | Adenomatous polyposis coli protein isoform b. (2842 aa) |
| | SOX13 | SRY-box transcription factor 13. (615 aa) |
| | AXIN2 | Axin-2. (842 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (831 aa) |
| | AMER1 | APC membrane recruitment protein 1. (1134 aa) |
| | CCDC88C | Coiled-coil domain containing 88C. (2029 aa) |
| | CTNNB1 | Catenin beta 1. (774 aa) |
| | NOTUM | Notum, palmitoleoyl-protein carboxylesterase. (504 aa) |
| | PFDN5 | Prefoldin subunit 5 isoform alpha. (154 aa) |
| | TLE6 | TLE family member 6, subcortical maternal complex member. (573 aa) |
| | TLE2 | TLE family member 2, transcriptional corepressor. (745 aa) |
| | SHISA3 | Protein shisa-3 homolog. (237 aa) |
| | LRP4 | Low-density lipoprotein receptor-related protein 4. (1905 aa) |
| | KREMEN1 | Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (491 aa) |
| | DAB2IP | DAB2 interacting protein. (1192 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa) |
| | LMBR1L | Limb development membrane protein 1 like; Belongs to the LIMR family. (489 aa) |
| | NKD2 | NKD inhibitor of WNT signaling pathway 2. (400 aa) |
| | SDHAF2 | Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (361 aa) |
| | FRMD8 | FERM domain containing 8. (652 aa) |
| | CSNK1A1L | Casein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (332 aa) |
| | MESP1 | Mesoderm posterior bHLH transcription factor 1. (279 aa) |
| | TLE1 | TLE family member 1, transcriptional corepressor. (804 aa) |
| | SHISA6 | Shisa family member 6. (555 aa) |
| | ENSCJAP00000064692 | HORMA domain-containing protein. (211 aa) |
| | ENSCJAP00000065650 | Transcription factor 7 like 2. (649 aa) |
| | CTNNBIP1 | Beta-catenin-interacting protein 1. (81 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | SOX9 | Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa) |
| | ENSCJAP00000067889 | Hist_deacetyl domain-containing protein. (209 aa) |
| | TMEM64 | Transmembrane protein 64. (401 aa) |
| | ENSCJAP00000068726 | TLE_N domain-containing protein. (118 aa) |
| | FOXO1 | Fork-head domain-containing protein. (654 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa) |
| | ENSCJAP00000069660 | annotation not available (118 aa) |
| | ENSCJAP00000070021 | Uncharacterized protein. (129 aa) |
| | ENSCJAP00000070636 | WD_REPEATS_REGION domain-containing protein. (433 aa) |
| | AMER2 | APC membrane recruitment protein 2 isoform 2. (550 aa) |
| | ENSCJAP00000071129 | Fork-head domain-containing protein. (540 aa) |
| | APOA4 | Apolipoprotein A4. (400 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (476 aa) |
| | ENSCJAP00000073727 | Uncharacterized protein. (122 aa) |
| | BMP2 | Bone morphogenetic protein 2. (401 aa) |
| | ENSCJAP00000073823 | Zf-rbx1 domain-containing protein. (82 aa) |
| | SOX10 | Transcription factor SOX-10. (467 aa) |
| | RBMS3 | RNA binding motif single stranded interacting protein 3. (450 aa) |
| | DKK2 | Dickkopf_N domain-containing protein. (259 aa) |
| | ENSCJAP00000075085 | Uncharacterized protein. (120 aa) |
| | MLLT3 | MLLT3 super elongation complex subunit. (568 aa) |
| | ENSCJAP00000075573 | Protein kinase domain-containing protein. (310 aa) |
| | ENSCJAP00000075657 | Uncharacterized protein. (113 aa) |
| | NKX2-5 | NK2 homeobox 5. (324 aa) |
| | DACT3 | Dishevelled binding antagonist of beta catenin 3. (719 aa) |
| | ENSCJAP00000075867 | Sclerostin. (213 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa) |
| | ANKRD6 | Ankyrin repeat domain 6. (742 aa) |
| | SOX17 | SRY-box transcription factor 17. (414 aa) |
| | DKK1 | Dickkopf_N domain-containing protein. (332 aa) |
| | PTPRU | Protein tyrosine phosphatase receptor type U. (1452 aa) |
| | ENSCJAP00000077875 | Uncharacterized protein. (109 aa) |
| | PFDN5-2 | Prefoldin subunit 5 isoform gamma. (109 aa) |
| | FRZB | Frizzled related protein. (412 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (540 aa) |
