STRINGSTRING
EPN2 EPN2 IL12A IL12A PTPN1 PTPN1 VWC2 VWC2 BMPER BMPER HTRA1 HTRA1 EMILIN1 EMILIN1 HGS HGS SKOR1 SKOR1 HTRA4 HTRA4 CTDSPL2 CTDSPL2 SKI SKI AGTR2 AGTR2 ADGRA2 ADGRA2 TNFAIP6 TNFAIP6 FUZ FUZ DAND5 DAND5 SULF1 SULF1 GDF3 GDF3 LRP2 LRP2 ATP2B4 ATP2B4 NBL1 NBL1 SORL1 SORL1 WNT5A WNT5A PRDM14 PRDM14 HHEX HHEX NOTCH1 NOTCH1 SFRP1 SFRP1 VWC2L VWC2L MMRN2 MMRN2 CREB3L1 CREB3L1 SULF2 SULF2 ENSCJAP00000078916 ENSCJAP00000078916 XDH XDH DKK1 DKK1 ENSCJAP00000075867 ENSCJAP00000075867 CXCL13 CXCL13 TWSG1 TWSG1 TMPRSS6 TMPRSS6 SHISA2 SHISA2 THBS1 THBS1 WNT4 WNT4 SPRY3 SPRY3 CRIM1 CRIM1 SPRY2 SPRY2 ABL1 ABL1 NEDD4 NEDD4 AGT AGT SEMA6A SEMA6A ENSCJAP00000063916 ENSCJAP00000063916 SMAD7 SMAD7 DLX1 DLX1 SOSTDC1 SOSTDC1 CHRDL1 CHRDL1 SMURF2 SMURF2 HJV HJV GREM2 GREM2 CASK CASK SMAD6 SMAD6 SKOR2 SKOR2 SMURF1 SMURF1 NOG NOG GATA3 GATA3 UBE2D1 UBE2D1 SPRY4 SPRY4 PIK3CB PIK3CB SFRP2 SFRP2 LEMD2 LEMD2 FBN1 FBN1 SPRY1 SPRY1 F7GUC0_CALJA F7GUC0_CALJA WNT1 WNT1 DAB2IP DAB2IP DCN DCN PPM1A PPM1A IL12B IL12B GPC1 GPC1 ADAMTS12 ADAMTS12 SPG20 SPG20 NIBAN2 NIBAN2 CHRDL2 CHRDL2 CHRD CHRD LEMD3 LEMD3 HRG HRG NF1 NF1 HIPK2 HIPK2 BAMBI BAMBI FSTL3 FSTL3 SLIT2 SLIT2 TRIM33 TRIM33 CER1 CER1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPN2Epsin-2 isoform b. (638 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
BMPERBMP binding endothelial regulator. (686 aa)
HTRA1HtrA serine peptidase 1. (522 aa)
EMILIN1Elastin microfibril interfacer 1. (1016 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (761 aa)
SKOR1SKI family transcriptional corepressor 1. (966 aa)
HTRA4HtrA serine peptidase 4. (476 aa)
CTDSPL2CTD small phosphatase-like protein 2. (466 aa)
SKISKI proto-oncogene. (729 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1328 aa)
TNFAIP6Tumor necrosis factor-inducible gene 6 protein. (277 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
DAND5DAN domain BMP antagonist family member 5. (189 aa)
SULF1Sulfatase 1. (1133 aa)
GDF3Growth differentiation factor 3. (364 aa)
LRP2LDL receptor related protein 2. (4656 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1169 aa)
NBL1NBL1, DAN family BMP antagonist. (216 aa)
SORL1Sortilin related receptor 1. (2307 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PRDM14Uncharacterized protein. (571 aa)
HHEXHematopoietically-expressed homeobox protein HHEX. (270 aa)
NOTCH1Notch receptor 1. (2551 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (219 aa)
MMRN2Multimerin 2. (949 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
SULF2Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. (902 aa)
ENSCJAP00000078916Uncharacterized protein. (515 aa)
XDHXanthine dehydrogenase. (1333 aa)
DKK1Dickkopf_N domain-containing protein. (332 aa)
ENSCJAP00000075867Sclerostin. (213 aa)
CXCL13C-X-C motif chemokine ligand 13. (104 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (219 aa)
TMPRSS6Transmembrane serine protease 6; Belongs to the peptidase S1 family. (709 aa)
SHISA2Shisa family member 2. (295 aa)
THBS1Thrombospondin 1. (1178 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
SPRY3Sprouty RTK signaling antagonist 3. (288 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1036 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
NEDD4NEDD4 E3 ubiquitin protein ligase. (1319 aa)
AGTAngiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family. (491 aa)
SEMA6ASema domain-containing protein; Belongs to the semaphorin family. (1047 aa)
ENSCJAP00000063916Sema domain-containing protein; Belongs to the semaphorin family. (591 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
DLX1Homeobox protein DLX-1 isoform 1. (255 aa)
SOSTDC1CTCK domain-containing protein. (230 aa)
CHRDL1Chordin-like protein 1 isoform 1. (458 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
HJVHemojuvelin BMP co-receptor. (422 aa)
GREM2Gremlin. (168 aa)
CASKUncharacterized protein; Belongs to the MAGUK family. (927 aa)
SMAD6Mothers against decapentaplegic homolog. (498 aa)
SKOR2SKI family transcriptional corepressor 2. (1013 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GATA3GATA binding protein 3. (444 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
SPRY4Sprouty RTK signaling antagonist 4. (321 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 1; Belongs to the PI3/PI4-kinase family. (1070 aa)
SFRP2Secreted frizzled related protein 2. (538 aa)
LEMD2LEM domain containing 2. (542 aa)
FBN1Fibrillin 1. (3018 aa)
SPRY1Sprouty RTK signaling antagonist 1. (356 aa)
F7GUC0_CALJAUncharacterized protein. (308 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
DAB2IPDAB2 interacting protein. (1192 aa)
DCNDecorin; May affect the rate of fibrils formation. (361 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
GPC1Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
ADAMTS12ADAM metallopeptidase with thrombospondin type 1 motif 12. (1600 aa)
SPG20Spartin. (666 aa)
NIBAN2Niban-like protein 1 isoform 1. (746 aa)
CHRDL2Chordin like 2. (452 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (967 aa)
LEMD3Inner nuclear membrane protein Man1 isoform 1. (911 aa)
HRGHistidine rich glycoprotein. (524 aa)
NF1Neurofibromin 1. (2839 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform 1. (1196 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
FSTL3Follistatin like 3. (267 aa)
SLIT2Slit guidance ligand 2. (1527 aa)
TRIM33E3 ubiquitin-protein ligase TRIM33 isoform alpha. (1127 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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