(39 nodes) Disordered domain specific binding network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FKBP8	Peptidylprolyl isomerase. (316 aa)
	TEAD2	TEA domain transcription factor 2. (320 aa)
	DFFB	DNA fragmentation factor subunit beta. (362 aa)
	EZR	Ezrin. (591 aa)
	SMAD2	Mothers against decapentaplegic homolog. (494 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	KEAP1	Kelch-like ECH-associated protein 1. (624 aa)
	F7I4B4_CALJA	Uncharacterized protein. (85 aa)
	F7EMI9_CALJA	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	SMTNL1	Smoothelin like 1. (570 aa)
	RB1	Retinoblastoma-associated protein. (927 aa)
	AP2A2	Adaptor related protein complex 2 subunit alpha 2. (756 aa)
	FN1	Fibronectin isoform 1 preproprotein. (2478 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (435 aa)
	RRM1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (792 aa)
	CTNNB1	Catenin beta 1. (774 aa)
	F7H580_CALJA	Glyceraldehyde-3-phosphate dehydrogenase. (319 aa)
	F7GX44_CALJA	Peptidylprolyl isomerase. (248 aa)
	ENSCJAP00000052715	Adaptin_N domain-containing protein. (165 aa)
	ENSCJAP00000053284	Glyceraldehyde-3-phosphate dehydrogenase. (332 aa)
	ENSCJAP00000056640	Uncharacterized protein; Belongs to the calmodulin family. (149 aa)
	CALML5	Calmodulin-like protein 5. (146 aa)
	CALM1	Uncharacterized protein; Belongs to the calmodulin family. (150 aa)
	CALML3	Calmodulin-like protein 3; Belongs to the calmodulin family. (149 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1681 aa)
	ENSCJAP00000064616	Glyceraldehyde-3-phosphate dehydrogenase. (328 aa)
	ENSCJAP00000064935	annotation not available (335 aa)
	ENSCJAP00000066250	Glyceraldehyde-3-phosphate dehydrogenase. (357 aa)
	ENSCJAP00000068307	Uncharacterized protein; Belongs to the calmodulin family. (95 aa)
	ENSCJAP00000069714	MH2 domain-containing protein. (253 aa)
	ENSCJAP00000070298	CIDE-N domain-containing protein. (93 aa)
	NUMA1	Nuclear mitotic apparatus protein 1. (2127 aa)
	CALM3	Calmodulin 3; Belongs to the calmodulin family. (203 aa)
	NCOA3	Nuclear receptor coactivator. (1485 aa)
	ENSCJAP00000074339	Uncharacterized protein. (102 aa)
	PPIL1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
	CDKN2A	Uncharacterized protein. (273 aa)
	ENSCJAP00000076812	ERM domain-containing protein. (114 aa)
	HSPA2	Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (641 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2A2	AP2M1	ENSCJAP00000021444	ENSCJAP00000023940	Adaptor related protein complex 2 subunit alpha 2.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.997
AP2A2	CLTC	ENSCJAP00000021444	ENSCJAP00000062424	Adaptor related protein complex 2 subunit alpha 2.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.950
AP2A2	ENSCJAP00000052715	ENSCJAP00000021444	ENSCJAP00000052715	Adaptor related protein complex 2 subunit alpha 2.	Adaptin_N domain-containing protein.	0.930
AP2M1	AP2A2	ENSCJAP00000023940	ENSCJAP00000021444	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Adaptor related protein complex 2 subunit alpha 2.	0.997
AP2M1	CLTC	ENSCJAP00000023940	ENSCJAP00000062424	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.973
AP2M1	ENSCJAP00000052715	ENSCJAP00000023940	ENSCJAP00000052715	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Adaptin_N domain-containing protein.	0.941
CALM1	CALML3	ENSCJAP00000059919	ENSCJAP00000061917	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin-like protein 3; Belongs to the calmodulin family.	0.901
CALM1	CALML5	ENSCJAP00000059919	ENSCJAP00000058230	Uncharacterized protein; Belongs to the calmodulin family.	Calmodulin-like protein 5.	0.903
CALM1	ENSCJAP00000053284	ENSCJAP00000059919	ENSCJAP00000053284	Uncharacterized protein; Belongs to the calmodulin family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.436
CALM1	ENSCJAP00000064616	ENSCJAP00000059919	ENSCJAP00000064616	Uncharacterized protein; Belongs to the calmodulin family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.436
CALM1	ENSCJAP00000066250	ENSCJAP00000059919	ENSCJAP00000066250	Uncharacterized protein; Belongs to the calmodulin family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.436
CALM1	ENSCJAP00000074339	ENSCJAP00000059919	ENSCJAP00000074339	Uncharacterized protein; Belongs to the calmodulin family.	Uncharacterized protein.	0.847
CALM1	F7EMI9_CALJA	ENSCJAP00000059919	ENSCJAP00000015309	Uncharacterized protein; Belongs to the calmodulin family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.436
CALM1	F7H580_CALJA	ENSCJAP00000059919	ENSCJAP00000039153	Uncharacterized protein; Belongs to the calmodulin family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.436
CALM1	FKBP8	ENSCJAP00000059919	ENSCJAP00000048995	Uncharacterized protein; Belongs to the calmodulin family.	Peptidylprolyl isomerase.	0.578
CALM1	FYN	ENSCJAP00000059919	ENSCJAP00000009029	Uncharacterized protein; Belongs to the calmodulin family.	Tyrosine-protein kinase.	0.438
CALML3	CALM1	ENSCJAP00000061917	ENSCJAP00000059919	Calmodulin-like protein 3; Belongs to the calmodulin family.	Uncharacterized protein; Belongs to the calmodulin family.	0.901
CALML3	CALML5	ENSCJAP00000061917	ENSCJAP00000058230	Calmodulin-like protein 3; Belongs to the calmodulin family.	Calmodulin-like protein 5.	0.903
CALML3	ENSCJAP00000053284	ENSCJAP00000061917	ENSCJAP00000053284	Calmodulin-like protein 3; Belongs to the calmodulin family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.436
CALML3	ENSCJAP00000064616	ENSCJAP00000061917	ENSCJAP00000064616	Calmodulin-like protein 3; Belongs to the calmodulin family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.436