(12 nodes) Positive regulation of mitophagy in response to mitochondrial depolarization network (Callithrix jacchus)

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Your Input:
	ENSCJAP00000073330	Hist_deacetyl domain-containing protein. (262 aa)
	HUWE1	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4458 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (476 aa)
	ENSCJAP00000068982	Uncharacterized protein. (95 aa)
	ENSCJAP00000066433	Uncharacterized protein. (59 aa)
	TOMM7	Mitochondrial import receptor subunit TOM7 homolog. (55 aa)
	LOC100412918	Uncharacterized protein. (55 aa)
	MFN2	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
	OPTN	Optineurin. (578 aa)
	PINK1	Serine/threonine-protein kinase PINK1, mitochondrial. (581 aa)
	HDAC6	Histone deacetylase 6. (1254 aa)
	CDC37	Cell division cycle 37. (441 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC37	PINK1	ENSCJAP00000075134	ENSCJAP00000011996	Cell division cycle 37.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.784
ENSCJAP00000066433	PINK1	ENSCJAP00000066433	ENSCJAP00000011996	Uncharacterized protein.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.531
HDAC6	PRKN	ENSCJAP00000004409	ENSCJAP00000071706	Histone deacetylase 6.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.877
HUWE1	MFN2	ENSCJAP00000070595	ENSCJAP00000024872	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.538
HUWE1	PRKN	ENSCJAP00000070595	ENSCJAP00000071706	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.408
LOC100412918	PINK1	ENSCJAP00000058041	ENSCJAP00000011996	Uncharacterized protein.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.951
MFN2	HUWE1	ENSCJAP00000024872	ENSCJAP00000070595	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	0.538
MFN2	PINK1	ENSCJAP00000024872	ENSCJAP00000011996	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.996
MFN2	PRKN	ENSCJAP00000024872	ENSCJAP00000071706	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.997
OPTN	PINK1	ENSCJAP00000017595	ENSCJAP00000011996	Optineurin.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.404
PINK1	CDC37	ENSCJAP00000011996	ENSCJAP00000075134	Serine/threonine-protein kinase PINK1, mitochondrial.	Cell division cycle 37.	0.784
PINK1	ENSCJAP00000066433	ENSCJAP00000011996	ENSCJAP00000066433	Serine/threonine-protein kinase PINK1, mitochondrial.	Uncharacterized protein.	0.531
PINK1	LOC100412918	ENSCJAP00000011996	ENSCJAP00000058041	Serine/threonine-protein kinase PINK1, mitochondrial.	Uncharacterized protein.	0.951
PINK1	MFN2	ENSCJAP00000011996	ENSCJAP00000024872	Serine/threonine-protein kinase PINK1, mitochondrial.	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.996
PINK1	OPTN	ENSCJAP00000011996	ENSCJAP00000017595	Serine/threonine-protein kinase PINK1, mitochondrial.	Optineurin.	0.404
PINK1	PRKN	ENSCJAP00000011996	ENSCJAP00000071706	Serine/threonine-protein kinase PINK1, mitochondrial.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.999
PINK1	TOMM7	ENSCJAP00000011996	ENSCJAP00000065523	Serine/threonine-protein kinase PINK1, mitochondrial.	Mitochondrial import receptor subunit TOM7 homolog.	0.531
PRKN	HDAC6	ENSCJAP00000071706	ENSCJAP00000004409	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Histone deacetylase 6.	0.877
PRKN	HUWE1	ENSCJAP00000071706	ENSCJAP00000070595	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1.	0.408
PRKN	MFN2	ENSCJAP00000071706	ENSCJAP00000024872	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.997