STRINGSTRING
OTP OTP SIX3 SIX3 KDM2B KDM2B ELL3 ELL3 SMARCA1 SMARCA1 DCT DCT EGF EGF CIP2A CIP2A KDM1A KDM1A ID2 ID2 NES NES FOXG1 FOXG1 LRP2 LRP2 LHX2 LHX2 BTG2 BTG2 CTNNA1 CTNNA1 GLI1 GLI1 GLI3 GLI3 WNT5A WNT5A CDON CDON OPTN OPTN WDR62 WDR62 LHX5 LHX5 KIFAP3 KIFAP3 SMO SMO LIMS2 LIMS2 NOTCH1 NOTCH1 MDK MDK CEND1 CEND1 TRIM71 TRIM71 DRD2 DRD2 F7IMV6_CALJA F7IMV6_CALJA SIRT2 SIRT2 NF1 NF1 APPL2 APPL2 FZD3 FZD3 LYN LYN ZNF335 ZNF335 PTPRZ1 PTPRZ1 PITX3 PITX3 CTNNB1 CTNNB1 SHCBP1 SHCBP1 HIF1A HIF1A SMARCD3 SMARCD3 NF2 NF2 TGFB1 TGFB1 SHH SHH GATA2 GATA2 GPR37L1 GPR37L1 NR2E1 NR2E1 GJC2 GJC2 ASCL1 ASCL1 PROX1 PROX1 F7BYU4_CALJA F7BYU4_CALJA VEGFC VEGFC PTN PTN EMX1 EMX1 DMRTA2 DMRTA2 PAX6 PAX6 FZD9 FZD9 SLC16A2 SLC16A2 DLL4 DLL4 TOX TOX ID4 ID4 DISC1 DISC1 SPINT1 SPINT1 CX3CL1 CX3CL1 FOXO1 FOXO1 LRRK2 LRRK2 ENSCJAP00000070769 ENSCJAP00000070769 ENSCJAP00000071129 ENSCJAP00000071129 LHX1 LHX1 WNT3A WNT3A SOX10 SOX10 TAFA3 TAFA3 ADGRG1 ADGRG1 DISP3 DISP3 TAFA1 TAFA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OTPHomeobox protein orthopedia. (325 aa)
SIX3SIX homeobox 3. (331 aa)
KDM2BLysine demethylase 2B. (1246 aa)
ELL3Elongation factor RNA polymerase II-like 3 (Predicted). (398 aa)
SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1098 aa)
DCTDopachrome tautomerase. (519 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
CIP2ACell proliferation regulating inhibitor of protein phosphatase 2A. (747 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
ID2Inhibitor of DNA binding 2. (203 aa)
NESNestin; Belongs to the intermediate filament family. (1717 aa)
FOXG1Forkhead box G1. (505 aa)
LRP2LDL receptor related protein 2. (4656 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
CTNNA1Catenin alpha 1. (911 aa)
GLI1GLI family zinc finger 1. (1106 aa)
GLI3GLI family zinc finger 3. (1578 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CDONCell adhesion associated, oncogene regulated. (1264 aa)
OPTNOptineurin. (578 aa)
WDR62WD repeat-containing protein 62 isoform 1. (1525 aa)
LHX5LIM/homeobox protein Lhx5. (402 aa)
KIFAP3Kinesin associated protein 3. (827 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (365 aa)
NOTCH1Notch receptor 1. (2551 aa)
MDKMidkine isoform a. (144 aa)
CEND1Cell cycle exit and neuronal differentiation protein 1. (144 aa)
TRIM71Tripartite motif containing 71. (868 aa)
DRD2D(2) dopamine receptor isoform long; Belongs to the G-protein coupled receptor 1 family. (443 aa)
F7IMV6_CALJAUncharacterized protein. (146 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
NF1Neurofibromin 1. (2839 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (670 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (681 aa)
LYNTyrosine-protein kinase. (491 aa)
ZNF335Zinc finger protein 335. (1345 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2279 aa)
PITX3Homeobox protein. (302 aa)
CTNNB1Catenin beta 1. (774 aa)
SHCBP1SHC binding and spindle associated 1. (672 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (600 aa)
NF2Merlin isoform 1. (595 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
GATA2Endothelial transcription factor GATA-2 isoform 1. (480 aa)
GPR37L1G protein-coupled receptor 37 like 1. (481 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
GJC2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (439 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
PROX1Prospero homeobox protein 1. (737 aa)
F7BYU4_CALJAUncharacterized protein. (216 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (402 aa)
PTNUncharacterized protein. (182 aa)
EMX1Empty spiracles homeobox 1. (290 aa)
DMRTA2DMRT like family A2. (536 aa)
PAX6Paired box 6. (472 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
SLC16A2Solute carrier family 16 member 2. (535 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (718 aa)
TOXThymocyte selection-associated high mobility group box protein TOX. (526 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
DISC1Disrupted in schizophrenia 1 protein isoform L. (851 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (531 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (429 aa)
FOXO1Fork-head domain-containing protein. (654 aa)
LRRK2Leucine rich repeat kinase 2. (2506 aa)
ENSCJAP00000070769Polypyrimidine tract binding protein 2. (544 aa)
ENSCJAP00000071129Fork-head domain-containing protein. (540 aa)
LHX1LIM homeobox 1. (456 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SOX10Transcription factor SOX-10. (467 aa)
TAFA3TAFA chemokine like family member 3. (168 aa)
ADGRG1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (728 aa)
DISP3Dispatched RND transporter family member 3. (1392 aa)
TAFA1Uncharacterized protein. (172 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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