STRINGSTRING
ELL3 ELL3 DCT DCT EGF EGF CIP2A CIP2A KDM1A KDM1A NES NES FOXG1 FOXG1 LRP2 LRP2 LHX2 LHX2 GLI1 GLI1 GLI3 GLI3 CDON CDON OPTN OPTN WDR62 WDR62 LHX5 LHX5 SMO SMO NOTCH1 NOTCH1 MDK MDK DRD2 DRD2 FZD3 FZD3 LYN LYN ZNF335 ZNF335 PITX3 PITX3 CTNNB1 CTNNB1 HIF1A HIF1A SMARCD3 SMARCD3 OTP OTP SHH SHH GPR37L1 GPR37L1 NR2E1 NR2E1 GJC2 GJC2 ASCL1 ASCL1 PROX1 PROX1 F7BYU4_CALJA F7BYU4_CALJA VEGFC VEGFC DMRTA2 DMRTA2 PAX6 PAX6 FZD9 FZD9 DLL4 DLL4 TOX TOX ID4 ID4 DISC1 DISC1 CX3CL1 CX3CL1 LHX1 LHX1 WNT3A WNT3A SOX10 SOX10 ADGRG1 ADGRG1 DISP3 DISP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ELL3Elongation factor RNA polymerase II-like 3 (Predicted). (398 aa)
DCTDopachrome tautomerase. (519 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
CIP2ACell proliferation regulating inhibitor of protein phosphatase 2A. (747 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa)
NESNestin; Belongs to the intermediate filament family. (1717 aa)
FOXG1Forkhead box G1. (505 aa)
LRP2LDL receptor related protein 2. (4656 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
GLI1GLI family zinc finger 1. (1106 aa)
GLI3GLI family zinc finger 3. (1578 aa)
CDONCell adhesion associated, oncogene regulated. (1264 aa)
OPTNOptineurin. (578 aa)
WDR62WD repeat-containing protein 62 isoform 1. (1525 aa)
LHX5LIM/homeobox protein Lhx5. (402 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
NOTCH1Notch receptor 1. (2551 aa)
MDKMidkine isoform a. (144 aa)
DRD2D(2) dopamine receptor isoform long; Belongs to the G-protein coupled receptor 1 family. (443 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (681 aa)
LYNTyrosine-protein kinase. (491 aa)
ZNF335Zinc finger protein 335. (1345 aa)
PITX3Homeobox protein. (302 aa)
CTNNB1Catenin beta 1. (774 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (600 aa)
OTPHomeobox protein orthopedia. (325 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
GPR37L1G protein-coupled receptor 37 like 1. (481 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
GJC2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (439 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
PROX1Prospero homeobox protein 1. (737 aa)
F7BYU4_CALJAUncharacterized protein. (216 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (402 aa)
DMRTA2DMRT like family A2. (536 aa)
PAX6Paired box 6. (472 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (718 aa)
TOXThymocyte selection-associated high mobility group box protein TOX. (526 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
DISC1Disrupted in schizophrenia 1 protein isoform L. (851 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (429 aa)
LHX1LIM homeobox 1. (456 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SOX10Transcription factor SOX-10. (467 aa)
ADGRG1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (728 aa)
DISP3Dispatched RND transporter family member 3. (1392 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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