STRINGSTRING
IL18 IL18 F7IMV6_CALJA F7IMV6_CALJA LOC100384959 LOC100384959 CPB2 CPB2 TNFAIP3 TNFAIP3 XBP1 XBP1 RTN4 RTN4 PTN PTN FBXW7 FBXW7 ENSCJAP00000071395 ENSCJAP00000071395 WNT3A WNT3A CDKN2A CDKN2A GLI1 GLI1 F7I4B4_CALJA F7I4B4_CALJA MED1 MED1 HPN HPN LIMS2 LIMS2 MDK MDK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
F7IMV6_CALJAUncharacterized protein. (146 aa)
LOC100384959Uncharacterized protein. (523 aa)
CPB2Carboxypeptidase B2. (423 aa)
TNFAIP3Tumor necrosis factor alpha-induced protein 3. (790 aa)
XBP1BZIP domain-containing protein. (371 aa)
RTN4Reticulon. (986 aa)
PTNUncharacterized protein. (182 aa)
FBXW7F-box and WD repeat domain containing 7. (777 aa)
ENSCJAP00000071395BZIP domain-containing protein. (345 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CDKN2AUncharacterized protein. (273 aa)
GLI1GLI family zinc finger 1. (1106 aa)
F7I4B4_CALJAUncharacterized protein. (85 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
HPNSerine protease hepsin; Belongs to the peptidase S1 family. (417 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (365 aa)
MDKMidkine isoform a. (144 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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