STRINGSTRING
EPHA3 EPHA3 ROS1 ROS1 BLK BLK TIE1 TIE1 EPHB1 EPHB1 MAP3K11 MAP3K11 EPHA10 EPHA10 LMTK3 LMTK3 LCK LCK NRBP1 NRBP1 ERBB2 ERBB2 PDGFRB PDGFRB SRC SRC TNK2 TNK2 EPHB3 EPHB3 AATK AATK PTK2 PTK2 DDR2 DDR2 ERBB4 ERBB4 GUCY2F GUCY2F NEK7 NEK7 LIMK1 LIMK1 ABL2 ABL2 ABL1 ABL1 FGFR2 FGFR2 MAP3K12 MAP3K12 RIPK2 RIPK2 JAK3 JAK3 ANKK1 ANKK1 FLT1 FLT1 STYK1 STYK1 AXL AXL YES1 YES1 RYK RYK MAP3K7 MAP3K7 BRAF BRAF KSR2 KSR2 KIT KIT NTRK3 NTRK3 F7HFW4_CALJA F7HFW4_CALJA INSR INSR LMTK2 LMTK2 MUSK MUSK POMK POMK BMX BMX NEK6 NEK6 BMPR1A BMPR1A EPHA1 EPHA1 JAK2 JAK2 CSK CSK EPHA5 EPHA5 ILK ILK KSR1 KSR1 GUCY2C GUCY2C CSF1R CSF1R LTK LTK TYRO3 TYRO3 PTK2B PTK2B FLT3 FLT3 TXK TXK TEC TEC ITK ITK PDGFRA PDGFRA TEK TEK KDR KDR MAP3K21 MAP3K21 ACVRL1 ACVRL1 RIPK1 RIPK1 DSTYK DSTYK JAK1 JAK1 RAF1 RAF1 LYN LYN ROR1 ROR1 MERTK MERTK TNK1 TNK1 RET RET FER FER ACVR1 ACVR1 EPHB4 EPHB4 MAP3K13 MAP3K13 MAP3K9 MAP3K9 GUCY2D GUCY2D MAP3K10 MAP3K10 IRAK4 IRAK4 NTRK2 NTRK2 ARAF ARAF EPHA4 EPHA4 ERBB3 ERBB3 ZAP70 ZAP70 LIMK2 LIMK2 SRMS SRMS SCYL3 SCYL3 NPR2 NPR2 FES FES TESK1 TESK1 FGR FGR ALK ALK EPHA6 EPHA6 EPHA2 EPHA2 MAP3K20 MAP3K20 FGFR4 FGFR4 BMPR1B BMPR1B TYK2 TYK2 TNNI3K TNNI3K IGF1R IGF1R INSRR INSRR EPHB2 EPHB2 SYK SYK MET MET FYN FYN TESK2 TESK2 FRK FRK MST1R MST1R TGFBR2 TGFBR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPHA3Ephrin type-A receptor 3 isoform a. (984 aa)
ROS1Tyrosine-protein kinase receptor. (2347 aa)
BLKTyrosine-protein kinase. (464 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
EPHB1EPH receptor B1. (1055 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
EPHA10EPH receptor A10. (997 aa)
LMTK3Lemur tyrosine kinase 3. (1480 aa)
LCKTyrosine-protein kinase. (539 aa)
NRBP1Nuclear receptor binding protein 1. (543 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
SRCTyrosine-protein kinase. (553 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1118 aa)
EPHB3EPH receptor B3. (1013 aa)
AATKApoptosis associated tyrosine kinase. (1549 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (868 aa)
ERBB4Receptor protein-tyrosine kinase. (1331 aa)
GUCY2FGuanylate cyclase. (1108 aa)
NEK7Serine/threonine-protein kinase Nek7; Belongs to the protein kinase superfamily. (302 aa)
LIMK1LIM domain kinase 1 isoform 1. (640 aa)
ABL2Tyrosine-protein kinase. (1183 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (892 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
JAK3Tyrosine-protein kinase. (1117 aa)
ANKK1Ankyrin repeat and kinase domain containing 1. (764 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
STYK1Serine/threonine/tyrosine kinase 1. (426 aa)
AXLAXL receptor tyrosine kinase. (896 aa)
YES1Tyrosine-protein kinase. (548 aa)
RYKReceptor like tyrosine kinase. (629 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
BRAFUncharacterized protein. (805 aa)
KSR2Kinase suppressor of ras 2. (950 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (976 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
F7HFW4_CALJAUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (852 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
LMTK2Serine/threonine-protein kinase LMTK2. (1502 aa)
MUSKMuscle associated receptor tyrosine kinase. (881 aa)
POMKProtein kinase-like protein SgK196. (350 aa)
BMXTyrosine-protein kinase. (679 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (346 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
EPHA1EPH receptor A1. (987 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
CSKTyrosine-protein kinase. (450 aa)
EPHA5Ephrin type-A receptor 5 isoform a. (1038 aa)
ILKIntegrin linked kinase. (483 aa)
KSR1Kinase suppressor of ras 1. (928 aa)
GUCY2CGuanylate cyclase. (1035 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
LTKTyrosine-protein kinase receptor. (863 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3. (890 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
TXKTyrosine-protein kinase. (600 aa)
TECTyrosine-protein kinase. (631 aa)
ITKTyrosine-protein kinase. (620 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
TEKTEK receptor tyrosine kinase. (1074 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase. (1039 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (670 aa)
DSTYKDual serine/threonine and tyrosine protein kinase isoform 1. (928 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (668 aa)
LYNTyrosine-protein kinase. (491 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
MERTKMER proto-oncogene, tyrosine kinase. (994 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (666 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (987 aa)
MAP3K9Uncharacterized protein. (1119 aa)
GUCY2DGuanylate cyclase. (1103 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (955 aa)
IRAK4Interleukin-1 receptor-associated kinase 4 isoform a. (460 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform 1. (611 aa)
EPHA4Ephrin type-A receptor 4. (986 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3 isoform 1. (1341 aa)
ZAP70Zeta chain of T cell receptor associated protein kinase 70. (648 aa)
LIMK2LIM domain kinase 2 isoform 2a. (639 aa)
SRMSTyrosine-protein kinase. (480 aa)
SCYL3Protein-associating with the carboxyl-terminal domain of ezrin isoform 2. (741 aa)
NPR2Guanylate cyclase. (1047 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
TESK1Dual specificity testis-specific protein kinase 1. (626 aa)
FGRTyrosine-protein kinase. (528 aa)
ALKTyrosine-protein kinase receptor. (1621 aa)
EPHA6EPH receptor A6. (1129 aa)
EPHA2EPH receptor A2. (976 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase MLT isoform 1. (800 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
TNNI3KUncharacterized protein. (835 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
EPHB2EPH receptor B2. (987 aa)
SYKUncharacterized protein. (636 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1353 aa)
FYNTyrosine-protein kinase. (537 aa)
TESK2Dual specificity testis-specific protein kinase 2. (571 aa)
FRKTyrosine-protein kinase. (505 aa)
MST1RMacrophage stimulating 1 receptor. (1399 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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