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| | CD80 | Uncharacterized protein. (348 aa) |
| | ENSCJAP00000078416 | Uncharacterized protein. (918 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (984 aa) |
| | BTC | Probetacellulin. (178 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa) |
| | STRN4 | Striatin 4. (743 aa) |
| | BANK1 | B cell scaffold protein with ankyrin repeats 1. (796 aa) |
| | FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (332 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | FGF18 | Uncharacterized protein; Belongs to the heparin-binding growth factors family. (378 aa) |
| | SRC | Tyrosine-protein kinase. (553 aa) |
| | CALCB | INSC_LBD domain-containing protein. (593 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (885 aa) |
| | ENSCJAP00000072746 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (454 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa) |
| | PIP5K1C | Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (663 aa) |
| | ENSCJAP00000071975 | Uncharacterized protein. (341 aa) |
| | IRS1 | Insulin receptor substrate 1. (1254 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (459 aa) |
| | CD19 | B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...] (623 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (300 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1331 aa) |
| | ICOS | Inducible T cell costimulator. (211 aa) |
| | CD28 | IGv domain-containing protein. (234 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform 1. (217 aa) |
| | EPGN-2 | Epithelial mitogen. (187 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1253 aa) |
| | FGFR2 | Fibroblast growth factor receptor. (822 aa) |
| | PIP5K1B | Phosphatidylinositol-4-phosphate 5-kinase type 1 beta. (555 aa) |
| | PIP4K2B | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta. (416 aa) |
| | EREG | Epiregulin. (169 aa) |
| | PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa) |
| | PPP4R4 | Serine/threonine-protein phosphatase 4 regulatory subunit 4 isoform 1. (873 aa) |
| | IER3 | Radiation-inducible immediate-early gene IEX-1. (156 aa) |
| | IL33 | Interleukin 33. (270 aa) |
| | NRG3 | Neuregulin 3. (720 aa) |
| | FGFR3 | Fibroblast growth factor receptor. (810 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa) |
| | PIK3AP1 | Phosphoinositide 3-kinase adapter protein 1. (805 aa) |
| | F7GTV7_CALJA | Uncharacterized protein. (151 aa) |
| | ENSCJAP00000056577 | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (277 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (218 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (976 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (765 aa) |
| | IRS2 | Insulin receptor substrate 2. (1327 aa) |
| | RHOG | Rho-related GTP-binding protein RhoG. (191 aa) |
| | INSR | Tyrosine-protein kinase receptor. (1382 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 1; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa) |
| | TRAT1 | T cell receptor associated transmembrane adaptor 1. (186 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (555 aa) |
| | EPGN | EGF-like domain-containing protein. (187 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (508 aa) |
| | NRG2 | Neuregulin 2. (847 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (845 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (385 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | FNBP4 | Formin-binding protein 4. (1019 aa) |
| | FAM102A | Family with sequence similarity 102 member A. (384 aa) |
| | PIP5KL1 | Phosphatidylinositol-4-phosphate 5-kinase like 1. (454 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa) |
| | ESR2 | Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation. (530 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa) |
| | FLT3 | Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa) |
| | TGFA | Transforming growth factor alpha. (165 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) |
| | KL | Klotho. (1012 aa) |
| | INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa) |
| | CD276 | CD276 molecule. (534 aa) |
| | LRRC40 | Leucine-rich repeat-containing protein 40. (602 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | WDR64 | WD repeat domain 64. (1121 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | SPEM1 | Spermatid maturation 1. (308 aa) |
| | SPEM2 | SPEM family member 2. (496 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1. (724 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa) |
| | PHLPP2 | PPM-type phosphatase domain-containing protein. (1357 aa) |
| | NARS2 | GRB2-associated-binding protein 2 isoform a. (676 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | IRAK1 | Interleukin-1 receptor-associated kinase 1 isoform 1 (Predicted). (712 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | IL1RAP | Interleukin-1 receptor accessory protein isoform 3. (687 aa) |
| | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa) |
| | AREG | Amphiregulin. (275 aa) |
| | IRAK4 | Interleukin-1 receptor-associated kinase 4 isoform a. (460 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (600 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | NRG4 | Neuregulin 4. (115 aa) |
| | ERBB3 | Receptor tyrosine-protein kinase erbB-3 isoform 1. (1341 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (537 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa) |
| | MYD88 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa) |
| | FNDC3A | Fibronectin type-III domain-containing protein 3A isoform 1. (1198 aa) |
| | IL1RL1 | Interleukin 1 receptor like 1. (557 aa) |
| | CD86 | Ig-like domain-containing protein. (361 aa) |
| | PIP4K2A | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha. (406 aa) |
| | NRG1 | Neuregulin 1. (713 aa) |
| | THEM4 | Thioesterase superfamily member 4. (238 aa) |
| | PIP5K1A | Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform 2. (550 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (801 aa) |
| | PIP4K2C | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform a. (421 aa) |
| | STRN3 | Striatin-3 isoform 1. (797 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1353 aa) |
| | PDGFA | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (443 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (600 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa) |
| | STRN | Striatin. (780 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (813 aa) |
| | PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1. (1710 aa) |
| | GAB1 | GRB2 associated binding protein 1. (751 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (646 aa) |
| | FAM102B | Family with sequence similarity 102 member B. (360 aa) |
| | FNDC3B | Fibronectin type III domain-containing protein 3B. (1204 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | LCK | Tyrosine-protein kinase. (539 aa) |
| | KLB | Klotho beta. (1045 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | FLT3LG | Fms related tyrosine kinase 3 ligand. (224 aa) |
