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| | ENSCJAP00000071263 | Helicase ATP-binding domain-containing protein. (88 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (540 aa) |
| | PIP4P2 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa) |
| | ENSCJAP00000078920 | Uncharacterized protein. (247 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (1085 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (556 aa) |
| | BRIP1 | Uncharacterized protein. (213 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1563 aa) |
| | ENSCJAP00000077446 | Uncharacterized protein. (317 aa) |
| | ENSCJAP00000077268 | Uncharacterized protein. (146 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1510 aa) |
| | NUAK1 | NUAK family SNF1-like kinase 1. (667 aa) |
| | ENSCJAP00000076896 | Uncharacterized protein. (567 aa) |
| | ENSCJAP00000075918 | Protein kinase domain-containing protein. (253 aa) |
| | ENSCJAP00000075765 | Uncharacterized protein. (260 aa) |
| | ENSCJAP00000075742 | Ubiquitin-like domain-containing protein. (156 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (748 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (241 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1927 aa) |
| | ENSCJAP00000074162 | CtIP_N domain-containing protein. (468 aa) |
| | ENSCJAP00000073788 | RRM domain-containing protein. (610 aa) |
| | ENSCJAP00000073702 | Uncharacterized protein. (153 aa) |
| | ENSCJAP00000073650 | Ubiquitin-like domain-containing protein. (156 aa) |
| | ENSCJAP00000073389 | Uncharacterized protein. (194 aa) |
| | ENSCJAP00000073047 | Uncharacterized protein. (179 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (571 aa) |
| | SMYD2 | N-lysine methyltransferase SMYD2. (433 aa) |
| | ENSCJAP00000072519 | Peptidyl-prolyl cis-trans isomerase. (152 aa) |
| | ENSCJAP00000071975 | Uncharacterized protein. (341 aa) |
| | ENSCJAP00000071842 | TAFII28 domain-containing protein. (203 aa) |
| | ENSCJAP00000071689 | Uncharacterized protein. (111 aa) |
| | NUAK2 | NUAK family kinase 2. (650 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1136 aa) |
| | MBD3 | Methyl-CpG binding domain protein 3. (380 aa) |
| | PPP1R13L | Protein phosphatase 1 regulatory subunit 13 like. (837 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (459 aa) |
| | ENSCJAP00000070871 | Ubiquitin-like domain-containing protein. (181 aa) |
| | ENSCJAP00000070800 | TAFII28 domain-containing protein. (203 aa) |
| | GATAD2B | GATA zinc finger domain containing 2B. (617 aa) |
| | ENSCJAP00000070008 | Uncharacterized protein. (89 aa) |
| | ENSCJAP00000069313 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (606 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (220 aa) |
| | ENSCJAP00000068152 | Uncharacterized protein. (132 aa) |
| | ENSCJAP00000067889 | Hist_deacetyl domain-containing protein. (209 aa) |
| | LOC100385218 | Ubiquitin-like domain-containing protein. (144 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | ENSCJAP00000067540 | TAFII28 domain-containing protein. (203 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | ENSCJAP00000067340 | Ubiquitin-like domain-containing protein. (143 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa) |
| | RPS27A-2 | ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | ENSCJAP00000065499 | Uncharacterized protein. (77 aa) |
| | RBBP4 | RB binding protein 4, chromatin remodeling factor. (425 aa) |
| | ENSCJAP00000064728 | Uncharacterized protein. (276 aa) |
| | PIP4K2B | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta. (416 aa) |
| | ENSCJAP00000064266 | Ubiquitin-like domain-containing protein. (155 aa) |
| | ENSCJAP00000064102 | Ubiquitin-like domain-containing protein. (147 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (345 aa) |
| | TP53RK | TP53-regulating kinase. (253 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (872 aa) |
| | MAPKAPK5 | MAP kinase-activated protein kinase 5 isoform 2. (473 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (364 aa) |
| | PRDM1 | PR/SET domain 1. (838 aa) |
| | ENSCJAP00000062353 | Protein kinase domain-containing protein. (229 aa) |
| | ZNF385C | Zinc finger protein 385C. (496 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (283 aa) |
| | ENSCJAP00000060911 | Ubiquitin-like domain-containing protein. (144 aa) |
| | ENSCJAP00000060543 | Uncharacterized protein. (520 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | SSRP1 | HMG box domain-containing protein. (828 aa) |
| | ENSCJAP00000059313 | Uncharacterized protein. (153 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (635 aa) |
| | LOC100411827 | Ubiquitin-like domain-containing protein. (127 aa) |
| | CDK5R1 | Cyclin-dependent kinase 5 activator. (307 aa) |
| | ENSCJAP00000057911 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (81 aa) |
| | UBC | Uncharacterized protein. (305 aa) |
| | TAF7 | Transcription initiation factor TFIID subunit 7. (349 aa) |
| | BANP | Uncharacterized protein. (121 aa) |
| | LOC100385843 | Uncharacterized protein. (147 aa) |
| | TAF12 | Transcription initiation factor TFIID subunit 12. (161 aa) |
| | ENSCJAP00000055417 | Ubiquitin-like domain-containing protein. (156 aa) |
| | POU4F1 | POU domain protein. (421 aa) |
| | RFC5 | Replication factor C subunit 5 isoform 1. (340 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (765 aa) |
| | GATAD2A | GATA zinc finger domain containing 2A. (748 aa) |
| | ENSCJAP00000053805 | Uncharacterized protein. (124 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (163 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | ENSCJAP00000052511 | Ubiquitin-like domain-containing protein. (77 aa) |
| | FOXP4 | Forkhead box protein P4 isoform 1. (679 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (345 aa) |
| | HIPK4 | Homeodomain interacting protein kinase 4. (616 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa) |
| | UBA52 | Ubiquitin-like domain-containing protein. (137 aa) |
| | LOC100398346 | RAD50 homolog isoform 1 (Predicted). (1312 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (555 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (464 aa) |
| | DYRK2 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform 2. (601 aa) |
| | TAF11 | Transcription initiation factor TFIID subunit 11 isoform 1. (211 aa) |
| | BRD9 | Bromodomain containing 9. (599 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | CHEK2 | Uncharacterized protein. (543 aa) |
| | BLM | BLM RecQ like helicase. (1415 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (713 aa) |
| | F6Q3J9_CALJA | Ubiquitin-like domain-containing protein. (155 aa) |
| | F7FKC4_CALJA | FHA domain-containing protein. (300 aa) |
| | ZNF385B | Zinc finger protein 385B. (499 aa) |
| | HIPK3 | Homeodomain-interacting protein kinase 3 isoform 1. (1216 aa) |
| | RMI1 | RecQ-mediated genome instability protein 1. (625 aa) |
| | MBD3L1 | Methyl-CpG binding domain protein 3 like 1. (222 aa) |
| | F7IQS9_CALJA | Ubiquitin-like domain-containing protein. (155 aa) |
| | DAXX | Death domain-associated protein 6 isoform a. (742 aa) |
| | RECQL4 | RecQ like helicase 4. (1204 aa) |
| | POU4F3 | POU domain protein. (338 aa) |
| | CSNK2A1 | Casein kinase II subunit alpha isoform a; Belongs to the protein kinase superfamily. (391 aa) |
| | PRKAG1 | Uncharacterized protein. (340 aa) |
| | TPX2 | TPX2 microtubule nucleation factor. (741 aa) |
| | TAF4B | TATA-box binding protein associated factor 4b. (868 aa) |
| | TAF3 | TATA-box binding protein associated factor 3. (931 aa) |
| | TBP | TATA-box binding protein. (332 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (306 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (988 aa) |
| | TAF9B | TATA-box binding protein associated factor 9b. (312 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (987 aa) |
| | MTA2 | Metastasis associated 1 family member 2. (668 aa) |
| | ZNF385A | Zinc finger protein 385A. (389 aa) |
| | RHNO1 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 isoform 1. (240 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (580 aa) |
| | RFC3 | Replication factor C subunit 3 isoform 1. (356 aa) |
| | TAF5 | Transcription initiation factor TFIID subunit 5. (800 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (421 aa) |
| | PML | Promyelocytic leukemia. (881 aa) |
| | PHF20 | PHD finger protein 20. (1012 aa) |
| | EXO1 | Exonuclease 1. (852 aa) |
| | PPP1R13B | Protein phosphatase 1 regulatory subunit 13B. (1090 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa) |
| | KMT5A | Lysine methyltransferase 5A. (352 aa) |
| | BRD1 | Bromodomain containing 1. (1189 aa) |
| | RAD17 | Cell cycle checkpoint protein RAD17 isoform 2. (681 aa) |
| | BRPF1 | Uncharacterized protein. (1220 aa) |
| | RMI2 | Uncharacterized protein. (84 aa) |
| | BRPF3 | Bromodomain and PHD finger-containing protein 3. (1205 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | L3MBTL4 | L3MBTL histone methyl-lysine binding protein 4. (630 aa) |
| | CCNG1 | Cyclin-G1; Belongs to the cyclin family. (295 aa) |
| | MLST8 | Target of rapamycin complex subunit LST8 isoform a. (326 aa) |
| | TAF15 | TATA-box binding protein associated factor 15. (592 aa) |
| | EXD2 | Exonuclease 3'-5' domain-containing protein 2 isoform 1. (621 aa) |
| | C17orf113 | Chromosome 17 open reading frame 113. (675 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform 1. (556 aa) |
| | CHD3 | Chromodomain helicase DNA binding protein 3. (2056 aa) |
| | MEIOB | Meiosis specific with OB-fold. (470 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | TXNDC11 | Thioredoxin domain-containing protein 11. (954 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | ING1 | Inhibitor of growth protein. (285 aa) |
| | TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (217 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | AIRE | Autoimmune regulator. (392 aa) |
| | HIPK2 | Homeodomain-interacting protein kinase 2 isoform 1. (1196 aa) |
| | HIPK1 | Uncharacterized protein. (1416 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1830 aa) |
| | WRN | WRN RecQ like helicase. (1433 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | CSNK2A2 | Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa) |
| | BARD1 | BRCA1 associated RING domain 1. (853 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (921 aa) |
| | AURKA | Aurora kinase A; Belongs to the protein kinase superfamily. (401 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform. (589 aa) |
| | SLF1 | Ankyrin repeat domain-containing protein 32. (1059 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (440 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (284 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (428 aa) |
| | SUPT16H | SPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | CHD4 | Chromodomain-helicase-DNA-binding protein 4. (1912 aa) |
| | PIP4K2A | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha. (406 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | KXD1 | KxDL motif containing 1. (175 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | PIP4K2C | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform a. (421 aa) |
| | MAPKAP1 | Target of rapamycin complex 2 subunit MAPKAP1 isoform 1. (522 aa) |
| | TAF2 | TATA-box binding protein associated factor 2. (1323 aa) |
| | ING2 | Inhibitor of growth protein. (279 aa) |
| | EP300 | E1A binding protein p300. (2426 aa) |
| | TAF7L | TATA-box binding protein associated factor 7 like. (496 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2005 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (709 aa) |
| | RFC2 | Replication factor C subunit 2. (352 aa) |
| | L3MBTL1 | Uncharacterized protein. (853 aa) |
| | TDRD3 | Tudor domain containing 3. (744 aa) |
| | L3MBTL3 | L3MBTL histone methyl-lysine binding protein 3. (796 aa) |
| | CCNA2 | Cyclin-A2; Belongs to the cyclin family. (432 aa) |
| | LY6G5B | Lymphocyte antigen 6 family member G5B. (200 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (234 aa) |
| | ATRIP | ATR-interacting protein isoform 1. (790 aa) |
| | TBPL1 | TATA box-binding protein-like protein 1. (186 aa) |
| | SGK1 | Non-specific serine/threonine protein kinase. (725 aa) |
| | TAF13 | Transcription initiation factor TFIID subunit 13. (124 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1268 aa) |
| | POU4F2 | POU domain protein. (408 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | SETD9 | SET domain-containing protein 9 isoform 1. (299 aa) |
| | MEAF6 | Chromatin modification-related protein MEAF6 isoform 1. (201 aa) |
| | BRD7 | Bromodomain containing 7. (652 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (628 aa) |
| | RNF34 | E3 ubiquitin-protein ligase RNF34 isoform 2. (372 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (391 aa) |
| | RPA3 | Replication protein A 14 kDa subunit. (121 aa) |
| | F6SBU8_CALJA | Uncharacterized protein. (386 aa) |
| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | CHD5 | Chromodomain helicase DNA binding protein 5. (2007 aa) |
| | AURKC | Aurora kinase C isoform 1; Belongs to the protein kinase superfamily. (309 aa) |
