(44 nodes) Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors network (Callithrix jacchus)

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Your Input:
	CGA	Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (151 aa)
	ATAD2	ATPase family AAA domain containing 2. (1390 aa)
	ERBB2	Receptor protein-tyrosine kinase. (1255 aa)
	TFAP2E	Transcription factor AP-2-epsilon. (442 aa)
	YEATS4	YEATS domain-containing protein 4. (227 aa)
	PITX2	Paired like homeodomain 2. (476 aa)
	EP300	E1A binding protein p300. (2426 aa)
	KDM5B	Lysine demethylase 5B. (1544 aa)
	DEK	DEK proto-oncogene. (381 aa)
	ATAD2B	ATPase family AAA domain containing 2B. (1458 aa)
	NOP2	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (810 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
	APOE	Apolipoprotein E. (320 aa)
	MYBL2	MYB proto-oncogene like 2. (700 aa)
	PITX3	Homeobox protein. (302 aa)
	TGFA	Transforming growth factor alpha. (165 aa)
	NPM1	Nucleophosmin isoform 1. (296 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	CREBBP	CREB-binding protein isoform a. (2449 aa)
	TFAP2A	Transcription factor AP-2 alpha. (439 aa)
	HSPD1	60 kDa heat shock protein, mitochondrial; Belongs to the chaperonin (HSP60) family. (573 aa)
	CITED1	Cbp/p300-interacting transactivator 1 isoform 2. (220 aa)
	TFAP2D	Transcription factor AP-2 delta. (456 aa)
	ENSCJAP00000053979	Nucleoplasmin domain-containing protein. (270 aa)
	KIT	Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (976 aa)
	ENSCJAP00000054920	Uncharacterized protein. (287 aa)
	KCTD15	BTB/POZ domain-containing protein KCTD15 isoform 2. (283 aa)
	ENSCJAP00000056513	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (570 aa)
	CITED2	Uncharacterized protein. (273 aa)
	ENSCJAP00000056948	Uncharacterized protein. (287 aa)
	CITED4	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4. (188 aa)
	KCTD1	BTB domain-containing protein. (867 aa)
	CDKN1A	Cyclin-dependent kinase inhibitor 1. (158 aa)
	FSHB	Follicle stimulating hormone beta subunit. (129 aa)
	ZFP42	Uncharacterized protein. (188 aa)
	EGFR	Receptor protein-tyrosine kinase. (1210 aa)
	TFAP2C	Transcription factor AP-2 gamma. (548 aa)
	ENSCJAP00000069517	Uncharacterized protein. (251 aa)
	PITX1	Homeobox protein. (314 aa)
	YY1	Transcriptional repressor protein YY1. (413 aa)
	TFAP2B	Transcription factor AP-2 beta. (569 aa)
	WWOX	WW domain-containing oxidoreductase isoform 1. (414 aa)
	ENSCJAP00000063716	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (530 aa)
	UBE2I	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOE	EGFR	ENSCJAP00000023984	ENSCJAP00000074658	Apolipoprotein E.	Receptor protein-tyrosine kinase.	0.471
APOE	ESR1	ENSCJAP00000023984	ENSCJAP00000036232	Apolipoprotein E.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.433
ATAD2	ESR1	ENSCJAP00000001567	ENSCJAP00000036232	ATPase family AAA domain containing 2.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.798
ATAD2B	ESR1	ENSCJAP00000014190	ENSCJAP00000036232	ATPase family AAA domain containing 2B.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.701
CDKN1A	CREBBP	ENSCJAP00000061908	ENSCJAP00000036680	Cyclin-dependent kinase inhibitor 1.	CREB-binding protein isoform a.	0.629
CDKN1A	EP300	ENSCJAP00000061908	ENSCJAP00000008779	Cyclin-dependent kinase inhibitor 1.	E1A binding protein p300.	0.673
CDKN1A	ESR1	ENSCJAP00000061908	ENSCJAP00000036232	Cyclin-dependent kinase inhibitor 1.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.498
CDKN1A	MYC	ENSCJAP00000061908	ENSCJAP00000023101	Cyclin-dependent kinase inhibitor 1.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.725
CGA	FSHB	ENSCJAP00000001086	ENSCJAP00000074962	Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.	Follicle stimulating hormone beta subunit.	0.918
CITED1	CREBBP	ENSCJAP00000051025	ENSCJAP00000036680	Cbp/p300-interacting transactivator 1 isoform 2.	CREB-binding protein isoform a.	0.855
CITED1	EP300	ENSCJAP00000051025	ENSCJAP00000008779	Cbp/p300-interacting transactivator 1 isoform 2.	E1A binding protein p300.	0.787
CITED1	TFAP2C	ENSCJAP00000051025	ENSCJAP00000070112	Cbp/p300-interacting transactivator 1 isoform 2.	Transcription factor AP-2 gamma.	0.496
CITED2	CREBBP	ENSCJAP00000056544	ENSCJAP00000036680	Uncharacterized protein.	CREB-binding protein isoform a.	0.894
CITED2	EP300	ENSCJAP00000056544	ENSCJAP00000008779	Uncharacterized protein.	E1A binding protein p300.	0.933
CITED2	TFAP2A	ENSCJAP00000056544	ENSCJAP00000039671	Uncharacterized protein.	Transcription factor AP-2 alpha.	0.663
CITED2	TFAP2B	ENSCJAP00000056544	ENSCJAP00000065573	Uncharacterized protein.	Transcription factor AP-2 beta.	0.465
CITED2	TFAP2C	ENSCJAP00000056544	ENSCJAP00000070112	Uncharacterized protein.	Transcription factor AP-2 gamma.	0.607
CITED2	TFAP2D	ENSCJAP00000056544	ENSCJAP00000052594	Uncharacterized protein.	Transcription factor AP-2 delta.	0.517
CITED2	TFAP2E	ENSCJAP00000056544	ENSCJAP00000002732	Uncharacterized protein.	Transcription factor AP-2-epsilon.	0.456
CITED4	CREBBP	ENSCJAP00000058142	ENSCJAP00000036680	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4.	CREB-binding protein isoform a.	0.892