STRINGSTRING
ELK1 ELK1 GNG8 GNG8 GNB1 GNB1 MMP3 MMP3 SHC1 SHC1 XPO1 XPO1 GNB3 GNB3 IGF1R IGF1R FOXO3 FOXO3 STRN3 STRN3 SRF SRF CAV2 CAV2 UHMK1 UHMK1 ZDHHC7 ZDHHC7 EGF EGF MMP7 MMP7 PRMT1 PRMT1 STRN STRN GNAT3 GNAT3 GNAI1 GNAI1 GNAI3 GNAI3 PRKCZ PRKCZ NRAS NRAS PIK3CA PIK3CA SPHK1 SPHK1 GNG7 GNG7 AREG AREG PIK3R2 PIK3R2 AKT2 AKT2 PDPK1 PDPK1 GNB2 GNB2 PIK3R1 PIK3R1 ENSCJAP00000078856 ENSCJAP00000078856 ENSCJAP00000078795 ENSCJAP00000078795 ENSCJAP00000078739 ENSCJAP00000078739 BTC BTC STRN4 STRN4 ENSCJAP00000076614 ENSCJAP00000076614 MMP2 MMP2 GNG4 GNG4 ENSCJAP00000075173 ENSCJAP00000075173 CAV1 CAV1 EGFR EGFR ENSCJAP00000074070 ENSCJAP00000074070 SRC SRC GNB4 GNB4 FOS FOS ENSCJAP00000072905 ENSCJAP00000072905 ENSCJAP00000072686 ENSCJAP00000072686 ENSCJAP00000071975 ENSCJAP00000071975 ENSCJAP00000071721 ENSCJAP00000071721 AKT1 AKT1 PTK2 PTK2 ENSCJAP00000070055 ENSCJAP00000070055 GNGT2 GNGT2 ERAS ERAS BCL2 BCL2 EPGN-2 EPGN-2 ENSCJAP00000066260 ENSCJAP00000066260 GNGT1 GNGT1 ENSCJAP00000065242 ENSCJAP00000065242 GNG10 GNG10 ENSCJAP00000065167 ENSCJAP00000065167 CSDE1 CSDE1 EREG EREG ENSCJAP00000063198 ENSCJAP00000063198 HRAS HRAS S1PR3 S1PR3 GNG12 GNG12 GNG2 GNG2 ZDHHC3 ZDHHC3 GNB5 GNB5 GNG11 GNG11 LOC103787193-2 LOC103787193-2 ENSCJAP00000060034 ENSCJAP00000060034 LOC103787193 LOC103787193 MAPK3 MAPK3 ZDHHC21 ZDHHC21 ENSCJAP00000057718 ENSCJAP00000057718 ENSCJAP00000057522 ENSCJAP00000057522 GNG3 GNG3 HBEGF HBEGF GNG13 GNG13 KRAS KRAS CCND1 CCND1 GNAI2 GNAI2 F7FNB2_CALJA F7FNB2_CALJA EPGN EPGN HSP90AA1 HSP90AA1 MAPK1 MAPK1 CDKN1B CDKN1B CREB1 CREB1 F7HZV8_CALJA F7HZV8_CALJA PIK3R3 PIK3R3 NOS3 NOS3 ESR2 ESR2 ESR1 ESR1 TGFA TGFA PRMT8 PRMT8 WDR64 WDR64 MMP9 MMP9 AKT3 AKT3 HSPB1 HSPB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ELK1ETS transcription factor ELK1. (479 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
MMP3Matrix metallopeptidase 3. (477 aa)
SHC1SHC-transforming protein 1 isoform 3. (577 aa)
XPO1Exportin-1. (1071 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
FOXO3Forkhead box protein O3. (672 aa)
STRN3Striatin-3 isoform 1. (797 aa)
SRFSerum response factor. (509 aa)
CAV2Caveolin-2; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (B [...] (162 aa)
UHMK1Serine/threonine-protein kinase Kist isoform 1. (419 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (345 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
MMP7Matrix metallopeptidase 7. (270 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (371 aa)
STRNStriatin. (780 aa)
GNAT3G protein subunit alpha transducin 3. (378 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. (354 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
NRASGTPase NRas. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SPHK1DAGKc domain-containing protein. (469 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
AREGAmphiregulin. (275 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform 1. (556 aa)
GNB2G protein subunit beta 2. (343 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1. (724 aa)
ENSCJAP00000078856Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
ENSCJAP00000078795Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (294 aa)
ENSCJAP00000078739Uncharacterized protein. (176 aa)
BTCProbetacellulin. (178 aa)
STRN4Striatin 4. (743 aa)
ENSCJAP00000076614SHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (127 aa)
MMP272 kDa type IV collagenase isoform a preproprotein. (660 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (106 aa)
ENSCJAP00000075173Uncharacterized protein. (340 aa)
CAV1Caveolin-1; May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependen [...] (178 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ENSCJAP00000074070Uncharacterized protein. (166 aa)
SRCTyrosine-protein kinase. (553 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
FOSProto-oncogene c-Fos. (380 aa)
ENSCJAP00000072905SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (185 aa)
ENSCJAP00000072686Uncharacterized protein. (174 aa)
ENSCJAP00000071975Uncharacterized protein. (341 aa)
ENSCJAP00000071721SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (119 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (459 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
ENSCJAP00000070055WD_REPEATS_REGION domain-containing protein. (171 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ERASES cell expressed Ras. (233 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
EPGN-2Epithelial mitogen. (187 aa)
ENSCJAP00000066260Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSCJAP00000065242WD_REPEATS_REGION domain-containing protein. (249 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSCJAP00000065167Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CSDE1Cold shock domain containing E1. (844 aa)
EREGEpiregulin. (169 aa)
ENSCJAP00000063198Uncharacterized protein. (133 aa)
HRASHRas proto-oncogene, GTPase. (209 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (350 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (107 aa)
ZDHHC3Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (361 aa)
GNB5G protein subunit beta 5. (395 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC103787193-2Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5. (68 aa)
ENSCJAP00000060034G protein gamma domain-containing protein. (65 aa)
LOC103787193Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
ENSCJAP00000057718Uncharacterized protein. (246 aa)
ENSCJAP00000057522Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
HBEGFHeparin binding EGF like growth factor. (218 aa)
GNG13G protein gamma domain-containing protein. (228 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (531 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2 isoform 1. (355 aa)
F7FNB2_CALJASHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (205 aa)
EPGNEGF-like domain-containing protein. (187 aa)
HSP90AA1HATPase_c domain-containing protein. (733 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform B. (341 aa)
F7HZV8_CALJAGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1203 aa)
ESR2Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation. (530 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
TGFATransforming growth factor alpha. (165 aa)
PRMT8Protein arginine N-methyltransferase 8 isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (394 aa)
WDR64WD repeat domain 64. (1121 aa)
MMP9Matrix metallopeptidase 9. (703 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (38%) [HD]