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NANOG | Homeobox domain-containing protein. (305 aa) | ||||
INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa) | ||||
ACR | Acrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. (402 aa) | ||||
PTPRZ1 | Protein tyrosine phosphatase receptor type Z1. (2279 aa) | ||||
TEKT1 | Tektin-1. (418 aa) | ||||
DAZL | Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). (316 aa) | ||||
MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa) | ||||
CTCF | Transcriptional repressor CTCF isoform 1. (727 aa) | ||||
CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (352 aa) | ||||
PIWIL1 | Piwi like RNA-mediated gene silencing 1; Belongs to the argonaute family. (861 aa) | ||||
LIF | LIF interleukin 6 family cytokine. (241 aa) | ||||
NANOS3 | Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (167 aa) | ||||
BOLL | Boule homolog, RNA binding protein. (295 aa) | ||||
KLF4 | Kruppel like factor 4. (507 aa) | ||||
POU5F1 | POU-specific domain-containing protein. (484 aa) | ||||
BMP7 | Bone morphogenetic protein 7. (430 aa) | ||||
BMP4 | Bone morphogenetic protein 4 preproprotein. (408 aa) | ||||
NANOS1 | Nanos C2HC-type zinc finger 1; Belongs to the nanos family. (413 aa) | ||||
NANOS2 | Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (141 aa) | ||||
KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (976 aa) | ||||
SOX2 | Transcription factor SOX-2. (319 aa) | ||||
BMP8A | Bone morphogenetic protein 8B preproprotein. (402 aa) | ||||
POU5F1-2 | Uncharacterized protein. (146 aa) |