STRINGSTRING
PYGL PYGL TKT TKT DCX DCX NES NES CRK CRK LOC100386265 LOC100386265 ENSCJAP00000074198 ENSCJAP00000074198 FOS FOS IRS1 IRS1 PXDN PXDN NPY NPY ENSCJAP00000065650 ENSCJAP00000065650 ENSCJAP00000065541 ENSCJAP00000065541 LOC100385283 LOC100385283 ENSCJAP00000063804 ENSCJAP00000063804 PYGB PYGB PYGM PYGM LOC100389168 LOC100389168 POMC POMC OLIG2 OLIG2 LOC100414113 LOC100414113 LOC100413207 LOC100413207 LOC100394573 LOC100394573 SOX21 SOX21 LOC100394455 LOC100394455 SIRT1 SIRT1 LOC100398205 LOC100398205 INS INS LEP LEP GHRL GHRL AGRP AGRP PXDNL PXDNL SST SST LOC100385831 LOC100385831
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
TKTTransketolase isoform 1. (623 aa)
DCXDoublecortin. (366 aa)
NESNestin; Belongs to the intermediate filament family. (1717 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
LOC100386265Histone domain-containing protein. (136 aa)
ENSCJAP00000074198Histone H3; Belongs to the histone H3 family. (124 aa)
FOSProto-oncogene c-Fos. (380 aa)
IRS1Insulin receptor substrate 1. (1254 aa)
PXDNUncharacterized protein. (691 aa)
NPYNeuropeptide Y. (133 aa)
ENSCJAP00000065650Transcription factor 7 like 2. (649 aa)
ENSCJAP00000065541Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100385283Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCJAP00000063804Histone H3; Belongs to the histone H3 family. (135 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (854 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (873 aa)
LOC100389168Histone H3; Belongs to the histone H3 family. (136 aa)
POMCPro-opiomelanocortin preproprotein. (265 aa)
OLIG2Oligodendrocyte lineage transcription factor 2 (Predicted). (323 aa)
LOC100414113Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100413207Histone H3; Belongs to the histone H3 family. (135 aa)
LOC100394573Histone H3; Belongs to the histone H3 family. (136 aa)
SOX21SRY-box transcription factor 21. (276 aa)
LOC100394455Histone H3; Belongs to the histone H3 family. (136 aa)
SIRT1Sirtuin 1. (753 aa)
LOC100398205Histone H3; Belongs to the histone H3 family. (136 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
GHRLAppetite-regulating hormone isoform 1 preproprotein. (117 aa)
AGRPAgouti related neuropeptide. (132 aa)
PXDNLPeroxidasin like. (1457 aa)
SSTSomatostatin preproprotein. (116 aa)
LOC100385831Histone H3; Belongs to the histone H3 family. (135 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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