STRINGSTRING
KLF4 KLF4 EGFR EGFR ENSCJAP00000074198 ENSCJAP00000074198 WNT3A WNT3A POU5F1 POU5F1 BMP4 BMP4 ESRRB ESRRB EPO EPO ENSCJAP00000065541 ENSCJAP00000065541 LOC100385283 LOC100385283 ENSCJAP00000063804 ENSCJAP00000063804 CDC42 CDC42 LOC100389168 LOC100389168 LOC100414113 LOC100414113 LOC100413207 LOC100413207 CBFB CBFB LOC100394573 LOC100394573 PTN PTN NPAS3 NPAS3 NOG NOG LOC100394455 LOC100394455 ASCL1 ASCL1 LOC100398205 LOC100398205 ATOH1 ATOH1 TGFB1 TGFB1 POU5F1-2 POU5F1-2 CREBBP CREBBP HIF1A HIF1A FLNA FLNA DLK1 DLK1 WNT3 WNT3 FGF4 FGF4 TGFB2 TGFB2 MYC MYC TNKS TNKS CXCR4 CXCR4 LOC100385831 LOC100385831 TNKS2 TNKS2 DNMT3A DNMT3A NR5A2 NR5A2 CD34 CD34 RUNX1 RUNX1 HES5 HES5 MTOR MTOR AHR AHR STAT3 STAT3 LOC100386265 LOC100386265
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KLF4Kruppel like factor 4. (507 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ENSCJAP00000074198Histone H3; Belongs to the histone H3 family. (124 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
POU5F1POU-specific domain-containing protein. (484 aa)
BMP4Bone morphogenetic protein 4 preproprotein. (408 aa)
ESRRBEstrogen related receptor beta. (454 aa)
EPOErythropoietin. (238 aa)
ENSCJAP00000065541Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100385283Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCJAP00000063804Histone H3; Belongs to the histone H3 family. (135 aa)
CDC42Cell division control protein 42 homolog isoform 1. (191 aa)
LOC100389168Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100414113Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100413207Histone H3; Belongs to the histone H3 family. (135 aa)
CBFBCore-binding factor subunit beta isoform 1. (187 aa)
LOC100394573Histone H3; Belongs to the histone H3 family. (136 aa)
PTNUncharacterized protein. (182 aa)
NPAS3Neuronal PAS domain protein 3. (937 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LOC100394455Histone H3; Belongs to the histone H3 family. (136 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
LOC100398205Histone H3; Belongs to the histone H3 family. (136 aa)
ATOH1Atonal bHLH transcription factor 1. (354 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
POU5F1-2Uncharacterized protein. (146 aa)
CREBBPCREB-binding protein isoform a. (2449 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
FLNAFilamin A. (2649 aa)
DLK1Uncharacterized protein. (713 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
TNKSPoly [ADP-ribose] polymerase. (1325 aa)
CXCR4C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (352 aa)
LOC100385831Histone H3; Belongs to the histone H3 family. (135 aa)
TNKS2Poly [ADP-ribose] polymerase. (1166 aa)
DNMT3AUncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (541 aa)
CD34Hematopoietic progenitor cell antigen CD34 isoform a. (386 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
HES5Hes family bHLH transcription factor 5. (162 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
AHRUncharacterized protein. (850 aa)
STAT3Signal transducer and activator of transcription. (771 aa)
LOC100386265Histone domain-containing protein. (136 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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