STRINGSTRING
NDUFA8 NDUFA8 EFHD1 EFHD1 NDUFS1 NDUFS1 TMEM11 TMEM11 LYRM7 LYRM7 ACAD8 ACAD8 ALDH1L2 ALDH1L2 SDHA SDHA NDUFA6 NDUFA6 CBR4 CBR4 SFXN2 SFXN2 LYRM2 LYRM2 CLPX CLPX COQ10B COQ10B IDH3B IDH3B MLYCD MLYCD TMTC1 TMTC1 EARS2 EARS2 NDUFA5 NDUFA5 AMACR AMACR NDUFA2 NDUFA2 TIMM17A TIMM17A NDUFV2 NDUFV2 PCCB PCCB COX4I1 COX4I1 TXNRD2 TXNRD2 OXCT1 OXCT1 LOC100385103 LOC100385103 NDUFC1 NDUFC1 ENSCJAP00000056007 ENSCJAP00000056007 COX8A COX8A LOC100414136 LOC100414136 THEM5 THEM5 FTH1 FTH1 MRPS30 MRPS30 ATP5MG ATP5MG KYNU KYNU COMT COMT ALAS1 ALAS1 PPARG PPARG HSPA9 HSPA9 SUCLA2 SUCLA2 NT5C3A NT5C3A ABCB10 ABCB10 AGXT2 AGXT2 ALDH5A1 ALDH5A1 LOC100393688 LOC100393688 COX7A1 COX7A1 NDUFB9 NDUFB9 PITRM1 PITRM1 ABHD10 ABHD10 NDUFS3 NDUFS3 PDHB PDHB IMMT IMMT ACSL5 ACSL5 MIPEP MIPEP USMG5 USMG5 SND1 SND1 TXN TXN HSD17B4 HSD17B4 LONP1 LONP1 IMMP2L IMMP2L SLC25A23 SLC25A23 MDH2 MDH2 RPL34 RPL34 AIFM3 AIFM3 DUS2 DUS2 DRG2 DRG2 HAGH HAGH ATP5PD ATP5PD BDH1 BDH1 VDAC1 VDAC1 ATP5PB ATP5PB UQCRQ UQCRQ TOMM40 TOMM40 NDUFB5 NDUFB5 PXMP2 PXMP2 GOT2 GOT2 COX7C COX7C ALDH7A1 ALDH7A1 ETFA ETFA NDUFA7 NDUFA7 PRODH PRODH NAGS NAGS IREB2 IREB2 IDH3A IDH3A DARS2 DARS2 LOC100389097 LOC100389097 ATPAF2 ATPAF2 FOXRED1 FOXRED1 LOC100395383 LOC100395383 HIBADH HIBADH TDRKH TDRKH SDHB SDHB NDUFB6 NDUFB6 ACO1 ACO1 SHMT2 SHMT2 ACSL4 ACSL4 SLC25A12 SLC25A12 LDHA LDHA DDAH1 DDAH1 OXR1 OXR1 PINK1 PINK1 PPM1K PPM1K TUFM TUFM NDUFA13 NDUFA13 PDHA1 PDHA1 NDUFS2 NDUFS2 ACO2 ACO2 PRDX2 PRDX2 PDK3 PDK3 NDUFB7 NDUFB7 RAB8B RAB8B NDUFB3 NDUFB3 UQCRC1 UQCRC1 PARK7 PARK7 MRPL42 MRPL42 NME6 NME6 SLC25A3 SLC25A3 ACP6 ACP6 CERK CERK LOC100395443 LOC100395443 MRPL40 MRPL40 PTRH2 PTRH2 VDAC2 VDAC2 COMTD1 COMTD1 SHMT1 SHMT1 NDUFV1 NDUFV1 TOMM70 TOMM70 VAMP1 VAMP1 DDX28 DDX28 LOC100403393 LOC100403393 HSDL1 HSDL1 PNKD PNKD MAP2 MAP2 SLC25A29 SLC25A29 PPA2 PPA2 LOC100392617 LOC100392617 COX7B COX7B QDPR QDPR SLC25A4 SLC25A4 TRMT10C TRMT10C ALDH1L1 ALDH1L1 TOMM40-2 TOMM40-2 GPX1 GPX1 NDUFS4 NDUFS4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NDUFA8NADH:ubiquinone oxidoreductase subunit A8. (244 aa)
EFHD1Uncharacterized protein. (235 aa)
NDUFS1NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa)
TMEM11Transmembrane protein 11, mitochondrial. (192 aa)
LYRM7LYR motif containing 7; Belongs to the complex I LYR family. (105 aa)
ACAD8Isobutyryl-CoA dehydrogenase, mitochondrial. (415 aa)
ALDH1L2Aldehyde dehydrogenase 1 family member L2; Belongs to the aldehyde dehydrogenase family. (941 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (664 aa)
NDUFA6NADH:ubiquinone oxidoreductase subunit A6; Belongs to the complex I LYR family. (154 aa)
CBR4Carbonyl reductase family member 4. (237 aa)
SFXN2Sidoreflexin. (322 aa)
LYRM2LYR motif containing 2; Belongs to the complex I LYR family. (98 aa)
CLPXATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial. (633 aa)
COQ10BCoenzyme Q-binding protein COQ10 homolog B, mitochondrial. (242 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
MLYCDMalonyl-CoA decarboxylase, mitochondrial. (493 aa)
TMTC1Transmembrane O-mannosyltransferase targeting cadherins 1. (881 aa)
EARS2Glutamyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (534 aa)
NDUFA5NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (116 aa)
AMACRAlpha-methylacyl-CoA racemase. (384 aa)
NDUFA2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
TIMM17AMitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (171 aa)
NDUFV2NADH:ubiquinone oxidoreductase core subunit V2. (249 aa)
PCCBUncharacterized protein. (568 aa)
COX4I1Cytochrome c oxidase subunit 4I1. (169 aa)
TXNRD2Thioredoxin reductase 2. (481 aa)
OXCT1Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (534 aa)
LOC10038510310 kDa heat shock protein, mitochondrial; Belongs to the GroES chaperonin family. (102 aa)
NDUFC1NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. (76 aa)
ENSCJAP00000056007Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (404 aa)
COX8ACytochrome c oxidase subunit 8A. (69 aa)
LOC100414136Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. (443 aa)
THEM5Thioesterase superfamily member 5. (247 aa)
FTH1Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (183 aa)
MRPS30Mitochondrial ribosomal protein S30. (432 aa)
ATP5MGATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (424 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (233 aa)
ALAS15'-aminolevulinate synthase 1. (738 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
HSPA9Stress-70 protein, mitochondrial; Belongs to the heat shock protein 70 family. (679 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (463 aa)
NT5C3A5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (336 aa)
ABCB10ATP-binding cassette sub-family B member 10, mitochondrial. (730 aa)
AGXT2Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (517 aa)
ALDH5A1Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (535 aa)
LOC100393688Creatine kinase, mitochondrial 1A (Predicted); Belongs to the ATP:guanido phosphotransferase family. (417 aa)
COX7A1Uncharacterized protein. (80 aa)
NDUFB9NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (185 aa)
PITRM1Pitrilysin metallopeptidase 1. (1038 aa)
ABHD10Alpha/beta hydrolase domain-containing protein 10, mitochondrial isoform 1. (306 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (262 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
IMMTMICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (737 aa)
ACSL5Acyl-CoA synthetase long chain family member 5. (750 aa)
MIPEPMitochondrial intermediate peptidase. (706 aa)
USMG5Up-regulated during skeletal muscle growth protein 5. (58 aa)
SND1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (910 aa)
TXNThioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] (219 aa)
HSD17B4Uncharacterized protein. (760 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...] (960 aa)
IMMP2LMitochondrial inner membrane protease subunit. (175 aa)
SLC25A23Solute carrier family 25 member 23; Belongs to the mitochondrial carrier (TC 2.A.29) family. (468 aa)
MDH2Malate dehydrogenase. (338 aa)
RPL34Uncharacterized protein. (117 aa)
AIFM3Apoptosis inducing factor mitochondria associated 3. (605 aa)
DUS2tRNA-dihydrouridine(20) synthase [NAD(P)+]-like isoform 1. (493 aa)
DRG2Developmentally-regulated GTP-binding protein 2. (364 aa)
HAGHHydroxyacylglutathione hydrolase, mitochondrial; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (308 aa)
ATP5PDATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
BDH1D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (343 aa)
VDAC1Voltage dependent anion channel 1. (357 aa)
ATP5PBATP synthase subunit b, mitochondrial. (256 aa)
UQCRQUbiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
TOMM40Translocase of outer mitochondrial membrane 40. (361 aa)
NDUFB5Uncharacterized protein. (189 aa)
PXMP2Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (195 aa)
GOT2Aspartate aminotransferase. (430 aa)
COX7CCytochrome c oxidase subunit 7C. (63 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (513 aa)
ETFAElectron transfer flavoprotein subunit alpha. (333 aa)
NDUFA7NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. (113 aa)
PRODHProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (600 aa)
NAGSN-acetylglutamate synthase. (534 aa)
IREB2Iron-responsive element-binding protein 2; Belongs to the aconitase/IPM isomerase family. (964 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
DARS2Aspartyl-tRNA synthetase 2, mitochondrial. (645 aa)
LOC100389097Cytochrome b-c1 complex subunit 2, mitochondrial. (453 aa)
ATPAF2ATP synthase mitochondrial F1 complex assembly factor 2. (289 aa)
FOXRED1FAD dependent oxidoreductase domain containing 1. (530 aa)
LOC100395383ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
HIBADH3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (336 aa)
TDRKHTudor and KH domain containing isoform a (Predicted). (560 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
NDUFB6Uncharacterized protein. (132 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (889 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (504 aa)
ACSL4Acyl-CoA synthetase long chain family member 4. (799 aa)
SLC25A12Calcium-binding mitochondrial carrier protein Aralar1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (678 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)
DDAH1N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 isoform 1. (285 aa)
OXR1Oxidation resistance 1. (883 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (581 aa)
PPM1KProtein phosphatase, Mg2+/Mn2+ dependent 1K. (372 aa)
TUFMElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (455 aa)
NDUFA13Uncharacterized protein. (151 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (426 aa)
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform 1; Belongs to the complex I 49 kDa subunit family. (463 aa)
ACO2Aconitase 2. (805 aa)
PRDX2Peroxiredoxin-2 isoform a. (198 aa)
PDK3Protein-serine/threonine kinase. (424 aa)
NDUFB7NADH:ubiquinone oxidoreductase subunit B7. (138 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
NDUFB3NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (98 aa)
UQCRC1Ubiquinol-cytochrome c reductase core protein 1. (491 aa)
PARK7Protein DJ-1. (189 aa)
MRPL42Uncharacterized protein. (154 aa)
NME6Nucleoside diphosphate kinase. (194 aa)
SLC25A3Solute carrier family 25 member 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (362 aa)
ACP6Lysophosphatidic acid phosphatase type 6; Belongs to the histidine acid phosphatase family. (428 aa)
CERKCeramide kinase. (448 aa)
LOC100395443Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa)
MRPL4039S ribosomal protein L40, mitochondrial. (207 aa)
PTRH2Peptidyl-tRNA hydrolase 2. (180 aa)
VDAC2Voltage-dependent anion-selective channel protein 2 isoform 2. (294 aa)
COMTD1Catechol O-methyltransferase domain-containing protein 1. (262 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (483 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
TOMM70Mitochondrial import receptor subunit TOM70. (608 aa)
VAMP1Vesicle associated membrane protein 1. (161 aa)
DDX28DEAD-box helicase 28. (546 aa)
LOC100403393Cytochrome b5 type B; Belongs to the cytochrome b5 family. (150 aa)
HSDL1Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (478 aa)
PNKDPNKD metallo-beta-lactamase domain containing. (424 aa)
MAP2Microtubule-associated protein. (1945 aa)
SLC25A29Mitochondrial carnitine/acylcarnitine carrier protein CACL; Belongs to the mitochondrial carrier (TC 2.A.29) family. (303 aa)
PPA2Pyrophosphatase (inorganic) 2. (345 aa)
LOC100392617Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (279 aa)
COX7BCytochrome c oxidase subunit 7B. (84 aa)
QDPRUncharacterized protein. (248 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (369 aa)
TRMT10CtRNA methyltransferase 10C, mitochondrial RNase P subunit. (424 aa)
ALDH1L1Aldehyde dehydrogenase 1 family member L1; Belongs to the aldehyde dehydrogenase family. (944 aa)
TOMM40-2Uncharacterized protein. (241 aa)
GPX1Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. (141 aa)
NDUFS4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (175 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (18%) [HD]