(15 nodes) (2017) Dopamine Induces Oscillatory Activities in Human Midbrain Neurons with Parkin Mutations. network (Callithrix jacchus)

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Your Input:
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (476 aa)
	SOX4	Transcription factor SOX. (472 aa)
	PICK1	Protein interacting with PRKCA 1. (448 aa)
	KLF4	Kruppel like factor 4. (507 aa)
	SYNJ1	Synaptojanin 1. (1610 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
	POU5F1-2	Uncharacterized protein. (146 aa)
	NANOG	Homeobox domain-containing protein. (305 aa)
	SH3GL2	SH3 domain containing GRB2 like 2, endophilin A1. (380 aa)
	FOXA2	Forkhead box A2. (456 aa)
	GDNF	Glial cell derived neurotrophic factor. (228 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
	EPS15	Epidermal growth factor receptor substrate 15 isoform A. (898 aa)
	SH3GL1	SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
	POU5F1	POU-specific domain-containing protein. (484 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EPS15	PRKN	ENSCJAP00000040151	ENSCJAP00000071706	Epidermal growth factor receptor substrate 15 isoform A.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.423
EPS15	SH3GL1	ENSCJAP00000040151	ENSCJAP00000076665	Epidermal growth factor receptor substrate 15 isoform A.	SH3 domain containing GRB2 like 1, endophilin A2.	0.753
EPS15	SH3GL2	ENSCJAP00000040151	ENSCJAP00000023303	Epidermal growth factor receptor substrate 15 isoform A.	SH3 domain containing GRB2 like 2, endophilin A1.	0.750
EPS15	SYNJ1	ENSCJAP00000040151	ENSCJAP00000044134	Epidermal growth factor receptor substrate 15 isoform A.	Synaptojanin 1.	0.750
FOXA2	GDNF	ENSCJAP00000010628	ENSCJAP00000014402	Forkhead box A2.	Glial cell derived neurotrophic factor.	0.573
FOXA2	KLF4	ENSCJAP00000010628	ENSCJAP00000077416	Forkhead box A2.	Kruppel like factor 4.	0.523
FOXA2	MYC	ENSCJAP00000010628	ENSCJAP00000023101	Forkhead box A2.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.404
FOXA2	NANOG	ENSCJAP00000010628	ENSCJAP00000035305	Forkhead box A2.	Homeobox domain-containing protein.	0.715
FOXA2	POU5F1	ENSCJAP00000010628	ENSCJAP00000071643	Forkhead box A2.	POU-specific domain-containing protein.	0.690
FOXA2	POU5F1-2	ENSCJAP00000010628	ENSCJAP00000036806	Forkhead box A2.	Uncharacterized protein.	0.690
FOXA2	SHH	ENSCJAP00000010628	ENSCJAP00000037954	Forkhead box A2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.816
GDNF	FOXA2	ENSCJAP00000014402	ENSCJAP00000010628	Glial cell derived neurotrophic factor.	Forkhead box A2.	0.573
GDNF	POU5F1	ENSCJAP00000014402	ENSCJAP00000071643	Glial cell derived neurotrophic factor.	POU-specific domain-containing protein.	0.448
GDNF	POU5F1-2	ENSCJAP00000014402	ENSCJAP00000036806	Glial cell derived neurotrophic factor.	Uncharacterized protein.	0.448
GDNF	SHH	ENSCJAP00000014402	ENSCJAP00000037954	Glial cell derived neurotrophic factor.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.699
KLF4	FOXA2	ENSCJAP00000077416	ENSCJAP00000010628	Kruppel like factor 4.	Forkhead box A2.	0.523
KLF4	MYC	ENSCJAP00000077416	ENSCJAP00000023101	Kruppel like factor 4.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.922
KLF4	NANOG	ENSCJAP00000077416	ENSCJAP00000035305	Kruppel like factor 4.	Homeobox domain-containing protein.	0.944
KLF4	POU5F1	ENSCJAP00000077416	ENSCJAP00000071643	Kruppel like factor 4.	POU-specific domain-containing protein.	0.949
KLF4	POU5F1-2	ENSCJAP00000077416	ENSCJAP00000036806	Kruppel like factor 4.	Uncharacterized protein.	0.949