9 items (Callithrix jacchus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DMD	Dystrophin. (3686 aa)
	SHANK3	SH3 and multiple ankyrin repeat domains 3. (1897 aa)
	HTT	Huntingtin. (3127 aa)
	MCPH1	Microcephalin isoform 1. (840 aa)
	UBE3A	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (876 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (497 aa)
	NLGN3	Neuroligin-3 isoform 1. (848 aa)
	SHANK1	SH3 and multiple ankyrin repeat domains 1. (2169 aa)
	FMR1	Uncharacterized protein. (650 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FMR1	HTT	ENSCJAP00000056898	ENSCJAP00000071701	Uncharacterized protein.	Huntingtin.	0.417
FMR1	MECP2	ENSCJAP00000056898	ENSCJAP00000026578	Uncharacterized protein.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	0.860
FMR1	NLGN3	ENSCJAP00000056898	ENSCJAP00000044818	Uncharacterized protein.	Neuroligin-3 isoform 1.	0.780
FMR1	SHANK1	ENSCJAP00000056898	ENSCJAP00000055562	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 1.	0.540
FMR1	SHANK3	ENSCJAP00000056898	ENSCJAP00000071806	Uncharacterized protein.	SH3 and multiple ankyrin repeat domains 3.	0.778
FMR1	UBE3A	ENSCJAP00000056898	ENSCJAP00000006911	Uncharacterized protein.	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	0.762
HTT	FMR1	ENSCJAP00000071701	ENSCJAP00000056898	Huntingtin.	Uncharacterized protein.	0.417
HTT	MECP2	ENSCJAP00000071701	ENSCJAP00000026578	Huntingtin.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	0.661
HTT	SHANK3	ENSCJAP00000071701	ENSCJAP00000071806	Huntingtin.	SH3 and multiple ankyrin repeat domains 3.	0.669
MECP2	FMR1	ENSCJAP00000026578	ENSCJAP00000056898	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	Uncharacterized protein.	0.860
MECP2	HTT	ENSCJAP00000026578	ENSCJAP00000071701	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	Huntingtin.	0.661
MECP2	NLGN3	ENSCJAP00000026578	ENSCJAP00000044818	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	Neuroligin-3 isoform 1.	0.708
MECP2	SHANK1	ENSCJAP00000026578	ENSCJAP00000055562	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	SH3 and multiple ankyrin repeat domains 1.	0.550
MECP2	SHANK3	ENSCJAP00000026578	ENSCJAP00000071806	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	SH3 and multiple ankyrin repeat domains 3.	0.793
MECP2	UBE3A	ENSCJAP00000026578	ENSCJAP00000006911	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	0.771
NLGN3	FMR1	ENSCJAP00000044818	ENSCJAP00000056898	Neuroligin-3 isoform 1.	Uncharacterized protein.	0.780
NLGN3	MECP2	ENSCJAP00000044818	ENSCJAP00000026578	Neuroligin-3 isoform 1.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	0.708
NLGN3	SHANK1	ENSCJAP00000044818	ENSCJAP00000055562	Neuroligin-3 isoform 1.	SH3 and multiple ankyrin repeat domains 1.	0.798
NLGN3	SHANK3	ENSCJAP00000044818	ENSCJAP00000071806	Neuroligin-3 isoform 1.	SH3 and multiple ankyrin repeat domains 3.	0.956
NLGN3	UBE3A	ENSCJAP00000044818	ENSCJAP00000006911	Neuroligin-3 isoform 1.	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	0.584