STRINGSTRING
IL3 IL3 HES5 HES5 EGF EGF FOXA2 FOXA2 NES NES DCX DCX GDNF GDNF LIF LIF SYN1 SYN1 MYC MYC TGFB2 TGFB2 LRTOMT LRTOMT TGFB1 TGFB1 SHH SHH YARS1 YARS1 MAOB MAOB SYN3 SYN3 ASCL1 ASCL1 COMT COMT FABP7 FABP7 MAOA MAOA IGF1 IGF1 PAX6 PAX6 OLIG2 OLIG2 GFAP GFAP TH TH EPO EPO BDNF BDNF KLF4 KLF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. (142 aa)
HES5Hes family bHLH transcription factor 5. (162 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
FOXA2Forkhead box A2. (456 aa)
NESNestin; Belongs to the intermediate filament family. (1717 aa)
DCXDoublecortin. (366 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
LIFLIF interleukin 6 family cytokine. (241 aa)
SYN1Synapsin I. (706 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
LRTOMTUncharacterized protein. (258 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
YARS1Tyrosine--tRNA ligase. (528 aa)
MAOBAmine oxidase. (520 aa)
SYN3Synapsin III isoform IIIa (Predicted). (580 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (232 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (233 aa)
FABP7Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (155 aa)
MAOAAmine oxidase. (930 aa)
IGF1Insulin like growth factor 1. (197 aa)
PAX6Paired box 6. (472 aa)
OLIG2Oligodendrocyte lineage transcription factor 2 (Predicted). (323 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (504 aa)
THTyrosine hydroxylase. (623 aa)
EPOErythropoietin. (238 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (330 aa)
KLF4Kruppel like factor 4. (507 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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