node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATF6 | DDIT3 | ENSCJAP00000008327 | ENSCJAP00000043609 | Activating transcription factor 6. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.986 |
ATF6 | ENSCJAP00000059748 | ENSCJAP00000008327 | ENSCJAP00000059748 | Activating transcription factor 6. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.986 |
BET1L | GOSR1 | ENSCJAP00000077904 | ENSCJAP00000067812 | Bet1 golgi vesicular membrane trafficking protein like. | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. | 0.997 |
CRX | OPN1SW | ENSCJAP00000039007 | ENSCJAP00000032955 | Cone-rod homeobox. | Opsin 1, short wave sensitive. | 0.596 |
CRX | RCVRN | ENSCJAP00000039007 | ENSCJAP00000023362 | Cone-rod homeobox. | Recoverin. | 0.848 |
CRX | RHO | ENSCJAP00000039007 | ENSCJAP00000031629 | Cone-rod homeobox. | Rhodopsin. | 0.824 |
DDIT3 | ATF6 | ENSCJAP00000043609 | ENSCJAP00000008327 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Activating transcription factor 6. | 0.986 |
DDIT3 | ENSCJAP00000059748 | ENSCJAP00000043609 | ENSCJAP00000059748 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.900 |
ENSCJAP00000059748 | ATF6 | ENSCJAP00000059748 | ENSCJAP00000008327 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | Activating transcription factor 6. | 0.986 |
ENSCJAP00000059748 | DDIT3 | ENSCJAP00000059748 | ENSCJAP00000043609 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.900 |
FGF2 | VTN | ENSCJAP00000077619 | ENSCJAP00000023190 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | SMB domain-containing protein. | 0.624 |
GOSR1 | BET1L | ENSCJAP00000067812 | ENSCJAP00000077904 | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. | Bet1 golgi vesicular membrane trafficking protein like. | 0.997 |
NCK1 | NCK2 | ENSCJAP00000004536 | ENSCJAP00000014923 | Cytoplasmic protein. | Cytoplasmic protein. | 0.961 |
NCK2 | NCK1 | ENSCJAP00000014923 | ENSCJAP00000004536 | Cytoplasmic protein. | Cytoplasmic protein. | 0.961 |
OPN1LW | OPN1SW | ENSCJAP00000070261 | ENSCJAP00000032955 | Opsin, longwave 563 nm; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | Opsin 1, short wave sensitive. | 0.744 |
OPN1LW | RCVRN | ENSCJAP00000070261 | ENSCJAP00000023362 | Opsin, longwave 563 nm; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | Recoverin. | 0.536 |
OPN1LW | RHO | ENSCJAP00000070261 | ENSCJAP00000031629 | Opsin, longwave 563 nm; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | Rhodopsin. | 0.645 |
OPN1SW | CRX | ENSCJAP00000032955 | ENSCJAP00000039007 | Opsin 1, short wave sensitive. | Cone-rod homeobox. | 0.596 |
OPN1SW | OPN1LW | ENSCJAP00000032955 | ENSCJAP00000070261 | Opsin 1, short wave sensitive. | Opsin, longwave 563 nm; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. | 0.744 |
OPN1SW | RCVRN | ENSCJAP00000032955 | ENSCJAP00000023362 | Opsin 1, short wave sensitive. | Recoverin. | 0.625 |