STRINGSTRING
CTSC CTSC SORT1 SORT1 GFAP GFAP TREML2 TREML2 CST7 CST7 CD19 CD19 LY9 LY9 PLCG2 PLCG2 GPR65 GPR65 CTSB CTSB KCNQ3 KCNQ3 C1QA C1QA CD33 CD33 CTSD CTSD THY1 THY1 ABCA7 ABCA7 ADAM10 ADAM10 CLDN5 CLDN5 LAMP1 LAMP1 CD68 CD68 KIT KIT EPHA1 EPHA1 B2M B2M GLS GLS TREM2 TREM2 PTPRC PTPRC CD4 CD4 CH25H CH25H CLEC7A CLEC7A CSF1R CSF1R ASB10 ASB10 PDCD1 PDCD1 PTK2B PTK2B FLT3 FLT3 CTSZ CTSZ PSEN1 PSEN1 ALB ALB INPP5D INPP5D APOE APOE BACE1 BACE1 SCN1B SCN1B CX3CR1 CX3CR1 SORL1 SORL1 DLK2 DLK2 ITGAX ITGAX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTSCDipeptidyl peptidase 1 isoform a preproprotein; Belongs to the peptidase C1 family. (460 aa)
SORT1Sortilin. (831 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (504 aa)
TREML2Ig-like domain-containing protein. (412 aa)
CST7Cystatin F. (178 aa)
CD19B-lymphocyte antigen CD19; Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens (By similarity). Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in [...] (623 aa)
LY9Lymphocyte antigen 9. (656 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1288 aa)
GPR65Psychosine receptor; Belongs to the G-protein coupled receptor 1 family. (337 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (367 aa)
KCNQ3Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family. (898 aa)
C1QAComplement C1q subcomponent subunit A. (245 aa)
CD33CD33 molecule. (389 aa)
CTSDPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (557 aa)
THY1Thy-1 cell surface antigen. (165 aa)
ABCA7ATP binding cassette subfamily A member 7. (2266 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10. (746 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (347 aa)
LAMP1Lysosomal associated membrane protein 1. (449 aa)
CD68Macrosialin isoform A. (343 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (976 aa)
EPHA1EPH receptor A1. (987 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa)
GLSGlutaminase kidney isoform, mitochondrial isoform 1. (669 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (388 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1252 aa)
CD4Ig-like domain-containing protein. (457 aa)
CH25HCholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (272 aa)
CLEC7AC-type lectin domain containing 7A. (246 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
ASB10Ankyrin repeat and SOCS box containing 10. (689 aa)
PDCD1Programmed cell death 1. (288 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
CTSZCathepsin Z; Belongs to the peptidase C1 family. (430 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (466 aa)
ALBAlbumin. (608 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1193 aa)
APOEApolipoprotein E. (320 aa)
BACE1Beta-secretase 1 isoform A preproprotein; Belongs to the peptidase A1 family. (501 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (218 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
SORL1Sortilin related receptor 1. (2307 aa)
DLK2Delta like non-canonical Notch ligand 2. (383 aa)
ITGAXCD11c protein; Belongs to the integrin alpha chain family. (1161 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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