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ATP6V0A1 ATP6V0A1 TMEM40 TMEM40 SERPINH1 SERPINH1 PLA2G4A PLA2G4A AMPD3 AMPD3 SETX SETX MAN1A1 MAN1A1 MAP4K4 MAP4K4 IL7 IL7 BCL2 BCL2 IL2RA IL2RA JAK3 JAK3 IL2 IL2 TMEM62 TMEM62 CMIP CMIP PALLD PALLD IFNG IFNG FOXP3 FOXP3 ATP13A2 ATP13A2 IL15 IL15 KRAS KRAS CCR5 CCR5 PLBD2 PLBD2 CHEK2 CHEK2 GLS GLS CD4 CD4 TGM2 TGM2 INO80C INO80C DDB2 DDB2 ATXN7 ATXN7 TMEM132A TMEM132A ATP6V0D1 ATP6V0D1 IRF6 IRF6 ANXA3 ANXA3 ITGB1 ITGB1 KRT20 KRT20 IL4 IL4 BRCA1 BRCA1 NSMCE2 NSMCE2 WEE1 WEE1 TRAF3 TRAF3 SIVA1 SIVA1 CHD7 CHD7 THBS3 THBS3 F7IR02_CALJA F7IR02_CALJA OSMR OSMR CDHR2 CDHR2 TMEM164 TMEM164 SKIL SKIL IL9 IL9 NIT1 NIT1 NUF2 NUF2 ITGA1 ITGA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP6V0A1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (844 aa)
TMEM40Transmembrane protein 40. (229 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (478 aa)
PLA2G4APhospholipase A2. (757 aa)
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (791 aa)
SETXSenataxin. (2719 aa)
MAN1A1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (681 aa)
MAP4K4Uncharacterized protein. (1369 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
IL2RAInterleukin-2 receptor subunit alpha. (272 aa)
JAK3Tyrosine-protein kinase. (1117 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
TMEM62Transmembrane protein 62. (648 aa)
CMIPC-Maf-inducing protein isoform C-Mip. (773 aa)
PALLDPalladin, cytoskeletal associated protein. (1399 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa)
FOXP3Forkhead box P3. (478 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1184 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
CCR5C-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
PLBD2Phospholipase B-like; Putative phospholipase. (589 aa)
CHEK2Uncharacterized protein. (543 aa)
GLSGlutaminase kidney isoform, mitochondrial isoform 1. (669 aa)
CD4Ig-like domain-containing protein. (457 aa)
TGM2Transglutaminase 2. (687 aa)
INO80CINO80 complex subunit C isoform 2. (192 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
ATXN7SCA7 domain-containing protein. (944 aa)
TMEM132ATransmembrane protein 132A. (1087 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (364 aa)
IRF6Interferon regulatory factor 6 isoform 1. (462 aa)
ANXA3Annexin. (323 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (1087 aa)
KRT20Keratin 20; Belongs to the intermediate filament family. (430 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (151 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1830 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (261 aa)
WEE1Wee1-like protein kinase. (642 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
SIVA1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (175 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2994 aa)
THBS3Thrombospondin-3 isoform 1. (956 aa)
F7IR02_CALJACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (422 aa)
OSMROncostatin M receptor. (977 aa)
CDHR2Cadherin related family member 2. (1321 aa)
TMEM164Transmembrane protein 164 isoform b. (297 aa)
SKILSKI like proto-oncogene. (683 aa)
IL9Interleukin 9. (144 aa)
NIT1Nitrilase 1. (327 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (464 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1182 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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