STRINGSTRING
SHANK3 SHANK3 IL17A IL17A NR4A1 NR4A1 IL6 IL6 HOMER1 HOMER1 SHANK1 SHANK1 EGR2 EGR2 BDNF BDNF FOS FOS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHANK3SH3 and multiple ankyrin repeat domains 3. (1897 aa)
IL17AInterleukin 17 A. (153 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (826 aa)
IL6Interleukin 6. (212 aa)
HOMER1Homer scaffold protein 1. (354 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2169 aa)
EGR2Early growth response 2. (486 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (330 aa)
FOSProto-oncogene c-Fos. (380 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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