(16 nodes) (2021) Valproic Acid Enhance Reprogramming of Bactrian Camel Cells through Promoting the Expression of Endogenous Gene c-Myc and the Process of Angiogenesis. network (Callithrix jacchus)

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Predicted Interactions

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Your Input:
	CRABP2	Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa)
	KLF4	Kruppel like factor 4. (507 aa)
	LYVE1	Lymphatic vessel endothelial hyaluronan receptor 1. (340 aa)
	POU5F1	POU-specific domain-containing protein. (484 aa)
	HDAC9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1096 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1124 aa)
	PAX6	Paired box 6. (472 aa)
	VEGFC	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (402 aa)
	POU5F1-2	Uncharacterized protein. (146 aa)
	NANOG	Homeobox domain-containing protein. (305 aa)
	CLDN7	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (990 aa)
	LIF	LIF interleukin 6 family cytokine. (241 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1035 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGF2	KLF4	ENSCJAP00000077619	ENSCJAP00000077416	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Kruppel like factor 4.	0.618
FGF2	LIF	ENSCJAP00000077619	ENSCJAP00000018988	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	LIF interleukin 6 family cytokine.	0.730
FGF2	MYC	ENSCJAP00000077619	ENSCJAP00000023101	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.565
FGF2	NANOG	ENSCJAP00000077619	ENSCJAP00000035305	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Homeobox domain-containing protein.	0.684
FGF2	PAX6	ENSCJAP00000077619	ENSCJAP00000057969	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Paired box 6.	0.628
FGF2	POU5F1	ENSCJAP00000077619	ENSCJAP00000071643	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	POU-specific domain-containing protein.	0.715
FGF2	POU5F1-2	ENSCJAP00000077619	ENSCJAP00000036806	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.715
FGF2	VEGFC	ENSCJAP00000077619	ENSCJAP00000053121	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.	0.559
HDAC4	HDAC5	ENSCJAP00000017313	ENSCJAP00000066305	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.417
HDAC4	HDAC9	ENSCJAP00000017313	ENSCJAP00000068919	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.404
HDAC5	HDAC4	ENSCJAP00000066305	ENSCJAP00000017313	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.417
HDAC9	HDAC4	ENSCJAP00000068919	ENSCJAP00000017313	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.404
KLF4	FGF2	ENSCJAP00000077416	ENSCJAP00000077619	Kruppel like factor 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.618
KLF4	LIF	ENSCJAP00000077416	ENSCJAP00000018988	Kruppel like factor 4.	LIF interleukin 6 family cytokine.	0.705
KLF4	MYC	ENSCJAP00000077416	ENSCJAP00000023101	Kruppel like factor 4.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).	0.922
KLF4	NANOG	ENSCJAP00000077416	ENSCJAP00000035305	Kruppel like factor 4.	Homeobox domain-containing protein.	0.944
KLF4	PAX6	ENSCJAP00000077416	ENSCJAP00000057969	Kruppel like factor 4.	Paired box 6.	0.575
KLF4	POU5F1	ENSCJAP00000077416	ENSCJAP00000071643	Kruppel like factor 4.	POU-specific domain-containing protein.	0.949
KLF4	POU5F1-2	ENSCJAP00000077416	ENSCJAP00000036806	Kruppel like factor 4.	Uncharacterized protein.	0.949
LIF	FGF2	ENSCJAP00000018988	ENSCJAP00000077619	LIF interleukin 6 family cytokine.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.730