STRINGSTRING
CDC42 CDC42 GUK1 GUK1 SIRT1 SIRT1 SMAD7 SMAD7 ICAM1 ICAM1 ACVR1C ACVR1C SMAD4 SMAD4 REN REN SMAD3 SMAD3 VCAM1 VCAM1 TGFBR2 TGFBR2 SMAD2 SMAD2 TBR1 TBR1 GLP1R GLP1R EZH2 EZH2 TGFB2 TGFB2 APOE APOE RHOA RHOA CCNB1 CCNB1 TGFB1 TGFB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC42Cell division control protein 42 homolog isoform 1. (191 aa)
GUK1Guanylate kinase-like domain-containing protein. (364 aa)
SIRT1Sirtuin 1. (753 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
ICAM1Intercellular adhesion molecule 1. (535 aa)
ACVR1CTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (579 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
RENRenin; Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. (400 aa)
SMAD3Mothers against decapentaplegic homolog. (437 aa)
VCAM1Vascular cell adhesion molecule 1. (739 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
SMAD2Mothers against decapentaplegic homolog. (494 aa)
TBR1T-box brain transcription factor 1. (682 aa)
GLP1RGlucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (455 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
APOEApolipoprotein E. (320 aa)
RHOATransforming protein RhoA. (193 aa)
CCNB1G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (429 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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