STRINGSTRING
SPHK2 SPHK2 LOC100386265 LOC100386265 PLG PLG FGF2 FGF2 PRKACG PRKACG ENSCJAP00000074198 ENSCJAP00000074198 POU5F1 POU5F1 ARRB1 ARRB1 FOXO1 FOXO1 LOC100408115 LOC100408115 PCNA PCNA ENSCJAP00000065541 ENSCJAP00000065541 LOC100385283 LOC100385283 ENSCJAP00000063804 ENSCJAP00000063804 PRKACA PRKACA LOC100389168 LOC100389168 LOC100414113 LOC100414113 LOC100413207 LOC100413207 PDCD6 PDCD6 LOC100394573 LOC100394573 PTEN PTEN KIT KIT RPS6 RPS6 CCND1 CCND1 LOC100394455 LOC100394455 PRKACB PRKACB PTPRC PTPRC CD44 CD44 LOC100398205 LOC100398205 RHEB RHEB POU5F1-2 POU5F1-2 NANOG NANOG TSC2 TSC2 SPHK1 SPHK1 RARA RARA MYC MYC ARRB2 ARRB2 APPL1 APPL1 LOC100385831 LOC100385831 MTOR MTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPHK2Sphingosine kinase 2. (662 aa)
LOC100386265Histone domain-containing protein. (136 aa)
PLGPlasminogen; Belongs to the peptidase S1 family. (837 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa)
PRKACGUncharacterized protein; Belongs to the protein kinase superfamily. (360 aa)
ENSCJAP00000074198Histone H3; Belongs to the histone H3 family. (124 aa)
POU5F1POU-specific domain-containing protein. (484 aa)
ARRB1Arrestin beta 1. (633 aa)
FOXO1Fork-head domain-containing protein. (654 aa)
LOC100408115Uncharacterized protein; Belongs to the protein kinase superfamily. (387 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ENSCJAP00000065541Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100385283Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCJAP00000063804Histone H3; Belongs to the histone H3 family. (135 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform 1; Belongs to the protein kinase superfamily. (351 aa)
LOC100389168Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100414113Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100413207Histone H3; Belongs to the histone H3 family. (135 aa)
PDCD6Programmed cell death 6. (191 aa)
LOC100394573Histone H3; Belongs to the histone H3 family. (136 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (976 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (531 aa)
LOC100394455Histone H3; Belongs to the histone H3 family. (136 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1252 aa)
CD44CD44 molecule (Indian blood group). (703 aa)
LOC100398205Histone H3; Belongs to the histone H3 family. (136 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
POU5F1-2Uncharacterized protein. (146 aa)
NANOGHomeobox domain-containing protein. (305 aa)
TSC2TSC complex subunit 2. (1794 aa)
SPHK1DAGKc domain-containing protein. (469 aa)
RARAUncharacterized protein. (468 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
ARRB2Beta-arrestin-2 isoform 1. (409 aa)
APPL1DCC-interacting protein 13-alpha. (709 aa)
LOC100385831Histone H3; Belongs to the histone H3 family. (135 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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