STRINGSTRING
JUN JUN COL4A2 COL4A2 THY1 THY1 FZD8 FZD8 KAT6B KAT6B NCOA3 NCOA3 CIITA CIITA SERPINE1 SERPINE1 HDAC9 HDAC9 WNT9A WNT9A FZD1 FZD1 HMOX1 HMOX1 FZD4 FZD4 WNT5B WNT5B MMP7 MMP7 COL1A1 COL1A1 COL3A1 COL3A1 WNT8A WNT8A WNT5A WNT5A TGFB2 TGFB2 IL13 IL13 IL4 IL4 MAPK8 MAPK8 FGF4 FGF4 COL4A1 COL4A1 WIF1 WIF1 WNT11 WNT11 MYSM1 MYSM1 WNT3 WNT3 DVL2 DVL2 HDAC3 HDAC3 IL10 IL10 DAAM1 DAAM1 TGFB1 TGFB1 ESCO1 ESCO1 CSNK1A1 CSNK1A1 SFRP2 SFRP2 IL6 IL6 GSK3B GSK3B GATA3 GATA3 HDAC8 HDAC8 SUV39H1 SUV39H1 AXL AXL HDAC5 HDAC5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
COL4A2Collagen type IV alpha 2 chain. (1798 aa)
THY1Thy-1 cell surface antigen. (165 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (680 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2066 aa)
NCOA3Nuclear receptor coactivator. (1485 aa)
CIITAClass II major histocompatibility complex transactivator. (1157 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (461 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1096 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (412 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
MMP7Matrix metallopeptidase 7. (270 aa)
COL1A1Collagen alpha-1(I) chain preproprotein. (1464 aa)
COL3A1Collagen alpha-1(III) chain preproprotein. (1465 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
IL13Uncharacterized protein. (146 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (151 aa)
MAPK8Mitogen-activated protein kinase. (450 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
COL4A1Collagen alpha-1(IV) chain preproprotein. (1669 aa)
WIF1Wnt inhibitory factor 1. (379 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (476 aa)
MYSM1Myb like, SWIRM and MPN domains 1. (846 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (736 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (178 aa)
DAAM1Disheveled-associated activator of morphogenesis 1 isoform 1. (1078 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (841 aa)
CSNK1A1Casein kinase I isoform alpha isoform 1; Belongs to the protein kinase superfamily. (365 aa)
SFRP2Secreted frizzled related protein 2. (538 aa)
IL6Interleukin 6. (212 aa)
GSK3BGlycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa)
GATA3GATA binding protein 3. (444 aa)
HDAC8Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (416 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (424 aa)
AXLAXL receptor tyrosine kinase. (896 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1124 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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