STRINGSTRING
EDAR EDAR KRT17 KRT17 AR AR GLI1 GLI1 NOTCH1 NOTCH1 PXDNL PXDNL SHH SHH TBP TBP WNT10B WNT10B WNT1 WNT1 BMPR1A BMPR1A FGF10 FGF10 NOG NOG LEF1 LEF1 PRDM1 PRDM1 LOX LOX BMP4 BMP4 PXDN PXDN PDGFRB PDGFRB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EDAREctodysplasin A receptor. (480 aa)
KRT17Keratin 17; Belongs to the intermediate filament family. (428 aa)
ARAndrogen receptor. (887 aa)
GLI1GLI family zinc finger 1. (1106 aa)
NOTCH1Notch receptor 1. (2551 aa)
PXDNLPeroxidasin like. (1457 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
TBPTATA-box binding protein. (332 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LEF1Lymphoid enhancer binding factor 1. (419 aa)
PRDM1PR/SET domain 1. (838 aa)
LOXLysyl oxidase. (417 aa)
BMP4Bone morphogenetic protein 4 preproprotein. (408 aa)
PXDNUncharacterized protein. (691 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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