(28 nodes) (2022) Sumoylation-deficient phosphoglycerate mutase 2 impairs myogenic differentiation. network (Callithrix jacchus)

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Your Input:
	PIAS1	Protein inhibitor of activated STAT 1. (653 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (540 aa)
	SENP2	SUMO specific peptidase 2. (650 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	SENP5	SUMO specific peptidase 5. (808 aa)
	SUMO2	Small ubiquitin-related modifier. (95 aa)
	SUMO1	Small ubiquitin-related modifier. (106 aa)
	ENSCJAP00000061564	Small ubiquitin-related modifier. (101 aa)
	NTN1	Netrin-1. (604 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
	MYOG	Myogenin. (249 aa)
	PGA	Pepsin A; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. (387 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (850 aa)
	HK1	Uncharacterized protein. (921 aa)
	PIAS4	Protein inhibitor of activated STAT 4. (509 aa)
	F7IG57_CALJA	Small ubiquitin-related modifier. (95 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
	ZIC3	Zinc finger protein ZIC 3. (467 aa)
	MYH8	Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
	MYH4	Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
	HKDC1	Hexokinase domain containing 1. (917 aa)
	HK2	Hexokinase-2. (917 aa)
	SUMO3	Small ubiquitin-related modifier. (103 aa)
	PGAM2	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
	PAX7	Paired box 7. (517 aa)
	HOXB13	Homeobox protein Hox-B13. (284 aa)
	HK3	Hexokinase 3. (923 aa)
	UNC5C	Unc-5 netrin receptor C. (931 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV3	MYOG	ENSCJAP00000075223	ENSCJAP00000043579	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Myogenin.	0.481
ENSCJAP00000061564	HDAC1	ENSCJAP00000061564	ENSCJAP00000079075	Small ubiquitin-related modifier.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.507
ENSCJAP00000061564	PIAS1	ENSCJAP00000061564	ENSCJAP00000004025	Small ubiquitin-related modifier.	Protein inhibitor of activated STAT 1.	0.929
ENSCJAP00000061564	PIAS4	ENSCJAP00000061564	ENSCJAP00000027775	Small ubiquitin-related modifier.	Protein inhibitor of activated STAT 4.	0.799
ENSCJAP00000061564	SENP2	ENSCJAP00000061564	ENSCJAP00000078328	Small ubiquitin-related modifier.	SUMO specific peptidase 2.	0.879
ENSCJAP00000061564	SENP5	ENSCJAP00000061564	ENSCJAP00000071077	Small ubiquitin-related modifier.	SUMO specific peptidase 5.	0.784
F7IG57_CALJA	HDAC1	ENSCJAP00000026777	ENSCJAP00000079075	Small ubiquitin-related modifier.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.520
F7IG57_CALJA	PIAS1	ENSCJAP00000026777	ENSCJAP00000004025	Small ubiquitin-related modifier.	Protein inhibitor of activated STAT 1.	0.916
F7IG57_CALJA	PIAS4	ENSCJAP00000026777	ENSCJAP00000027775	Small ubiquitin-related modifier.	Protein inhibitor of activated STAT 4.	0.848
F7IG57_CALJA	SENP2	ENSCJAP00000026777	ENSCJAP00000078328	Small ubiquitin-related modifier.	SUMO specific peptidase 2.	0.898
F7IG57_CALJA	SENP5	ENSCJAP00000026777	ENSCJAP00000071077	Small ubiquitin-related modifier.	SUMO specific peptidase 5.	0.782
HDAC1	ENSCJAP00000061564	ENSCJAP00000079075	ENSCJAP00000061564	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Small ubiquitin-related modifier.	0.507
HDAC1	F7IG57_CALJA	ENSCJAP00000079075	ENSCJAP00000026777	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Small ubiquitin-related modifier.	0.520
HDAC1	HIF1A	ENSCJAP00000079075	ENSCJAP00000035664	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Hypoxia inducible factor 1 subunit alpha.	0.721
HDAC1	SIRT2	ENSCJAP00000079075	ENSCJAP00000025710	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.560
HDAC1	SUMO1	ENSCJAP00000079075	ENSCJAP00000062736	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Small ubiquitin-related modifier.	0.539
HDAC1	SUMO2	ENSCJAP00000079075	ENSCJAP00000063370	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Small ubiquitin-related modifier.	0.520
HDAC1	SUMO3	ENSCJAP00000079075	ENSCJAP00000019420	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Small ubiquitin-related modifier.	0.520
HIF1A	HDAC1	ENSCJAP00000035664	ENSCJAP00000079075	Hypoxia inducible factor 1 subunit alpha.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.721
HIF1A	HK2	ENSCJAP00000035664	ENSCJAP00000023845	Hypoxia inducible factor 1 subunit alpha.	Hexokinase-2.	0.505